Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Boris Letribot"'
1
Akademický článek
Dual molecule targeting HDAC6 leads to intratumoral CD4+ cytotoxic lymphocytes recruitment through MHC-II upregulation on lung cancer cells
Autor: Harry Sokol, Chloé Michaudel, Sarah Ducellier, Mélanie Demeules, Boris Letribot, Massimiliano Gaetani, Abdallah Hamze, Mouad Alami, Mégane Nascimento, Sébastien Apcher
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Despite the current therapeutic treatments including surgery, chemotherapy, radiotherapy and more recently immunotherapy, the mortality rate of lung cancer stays high. Regarding lung cancer, epigenetic modifications altering cell cycle, an
Externí odkaz: https://doaj.org/article/a56f4a5f26594be8b75f2796e748ce1a
Zobrazit plný text záznamu
2
Akademický článek
Synthesis of 2-Mercapto-(2-Oxoindolin-3-Ylidene)Acetonitriles from 3-(4-Chloro-5H-1,2,3-Dithiazol-5-Ylidene)Indolin-2-ones
Autor: Boris Letribot, Régis Delatouche, Hervé Rouillard, Antoine Bonnet, Jean-René Chérouvrier, Lisianne Domon, Thierry Besson, Valérie Thiéry
Publikováno v: Molecules, Vol 23, Iss 6, p 1390 (2018)
Alkylidene oxindoles are important functional moieties and building blocks in pharmaceutical and synthetic chemistry. Our interest in biologically active compounds focused our studies on the synthesis of novel oxindoles, bearing on the exocyclic doub
Externí odkaz: https://doaj.org/article/b7d192764d9b4839b0edd7953b0286a7
Zobrazit plný text záznamu
5
Synthesis of N -Glycosyl-2-oxindoles by Pd-Catalyzed N-Arylation of 1-Amidosugars
Autor: Samir Messaoudi, Mouâd Alami, Wafa Redjdal, Belkacem Benmerad, Boris Letribot, Franck Le Bideau
Publikováno v: Organic Letters
Organic Letters, American Chemical Society, 2020, 22 (11), pp.4201-4206. ⟨10.1021/acs.orglett.0c01262⟩
International audience; An efficient intramolecular Pd-catalyzed N-arylation of o-iodo-amidosugars to the synthesis of N-glycosylated oxin-doles has been reported. The coupling reaction takes place in toluene and involves Pd(OAc)2/RuPhos catalytic sy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da879086c7831eeee788a8679cdd5cbd
https://hal.archives-ouvertes.fr/hal-03009606/document
Zobrazit plný text záznamu
7
Synthesis of 2-Mercapto-(2-Oxoindolin-3-Ylidene)Acetonitriles from 3-(4-Chloro-5H-1,2,3-Dithiazol-5-Ylidene)Indolin-2-ones
Autor: Lisianne Domon, Jean-René Chérouvrier, Valérie Thiéry, Régis Delatouche, Thierry Besson, Boris Letribot, Hervé Rouillard, Antoine Bonnet
Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Molecules, MDPI, 2018, 23 (6), pp.1390. ⟨10.3390/molecules23061390⟩
Volume 23
Issue 6
Molecules, Vol 23, Iss 6, p 1390 (2018)
Alkylidene oxindoles are important functional moieties and building blocks in pharmaceutical and synthetic chemistry. Our interest in biologically active compounds focused our studies on the synthesis of novel oxindoles, bearing on the exocyclic doub
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1087d3ce754f1359c98c5d838019d90c
http://europepmc.org/articles/PMC6100569
Zobrazit plný text záznamu
8
Optimization of Grignard ring-opening of α-brominated dioxolanes for the preparation of β-hydroxy-protected vinyl ethers by a three-step one-pot procedure
Autor: Boris Letribot, Emmanuelle Mounetou, Martine Bayle, Jean-Michel Chezal, Mathieu Andre
Publikováno v: Tetrahedron Letters. 53:6107-6110
Aliphatic, cyclic, and aromatic benzoate-protected γ-hydroxy enol ethers were prepared from α-brominated dioxolanes by a three-step reaction procedure and a one-pot protocol involving Grignard reagent formation, ring-opening, and final benzoate pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b58d66667a979d9280c6a1b6317c28d9
https://doi.org/10.1016/j.tetlet.2012.08.144
Zobrazit plný text záznamu
9
Use of copper(I) catalyzed azide alkyne cycloaddition (CuAAC) for the preparation of conjugated pyrrolo[2,3-a]carbazole Pim kinase inhibitors
Autor: Daniel Avignant, Rufine Akué-Gédu, Malika El-Ghozzi, Fabrice Anizon, Arnaud Gautier, Niina M. Santio, Federico Cisnetti, Boris Letribot, Päivi J. Koskinen, Pascale Moreau
Publikováno v: European Journal of Medicinal Chemistry. 50:304-310
We have previously demonstrated that pyrrolo[2,3-a]carbazole-3-carbaldehydes are potent Pim kinase inhibitors with in vitro antiproliferative activities. In the present study, we report the synthesis of new pyrrolocarbazoles substituted at the N-10 p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4c593ef659a4287439183561de1d8c
https://doi.org/10.1016/j.ejmech.2012.02.009
Zobrazit plný text záznamu
10
Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives
Autor: Rufine Akué-Gédu, Pascale Moreau, Eric Debiton, Boris Letribot, Fabrice Anizon, Emmanuelle Saugues
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 22:3807-3809
Development of potent and selective Pim kinase inhibitors has recently emerged as an important field for the design of new anti-cancer drugs. We report the synthesis of new N-10-substituted pyrrolo[2,3-a]carbazole derivatives and their evaluation as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5db7d1006941de8fa35eb7d0837c1dc
https://doi.org/10.1016/j.bmcl.2012.03.098
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje