Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Boris Kristof"'
Autor:
Cassandra Falckenhayn, Agata Bienkowska, Jörn Söhle, Katrin Wegner, Guenter Raddatz, Boris Kristof, Dirk Kuck, Ralf Siegner, Ronny Kaufmann, Julia Korn, Sascha Baumann, Daniela Lange, Andreas Schepky, Henry Völzke, Lars Kaderali, Marc Winnefeld, Frank Lyko, Elke Grönniger
Publikováno v:
Frontiers in Aging, Vol 4 (2024)
Changes in DNA methylation patterning have been reported to be a key hallmark of aged human skin. The altered DNA methylation patterns are correlated with deregulated gene expression and impaired tissue functionality, leading to the well-known skin a
Externí odkaz:
https://doaj.org/article/41b18a4c3c734ca79c31cb048d5cc259
Autor:
Agata Bienkowska, Günter Raddatz, Jörn Söhle, Boris Kristof, Henry Völzke, Stefan Gallinat, Frank Lyko, Lars Kaderali, Marc Winnefeld, Elke Grönniger, Cassandra Falckenhayn
Publikováno v:
Frontiers in Aging, Vol 4 (2024)
Aging is a complex process characterized by the gradual decline of physiological functions, leading to increased vulnerability to age-related diseases and reduced quality of life. Alterations in DNA methylation (DNAm) patterns have emerged as a funda
Externí odkaz:
https://doaj.org/article/1a63eb2abbed48d0819a01c6a91f55a4
Autor:
Nicholas Holzscheck, Cassandra Falckenhayn, Jörn Söhle, Boris Kristof, Ralf Siegner, André Werner, Janka Schössow, Clemens Jürgens, Henry Völzke, Horst Wenck, Marc Winnefeld, Elke Grönniger, Lars Kaderali
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract The development of ‘age clocks’, machine learning models predicting age from biological data, has been a major milestone in the search for reliable markers of biological age and has since become an invaluable tool in aging research. Howe
Externí odkaz:
https://doaj.org/article/777c395850e541569fc03b8d41e94be4
Autor:
Henry Völzke, Janka Schössow, Carsten Oliver Schmidt, Clemens Jürgens, Adrian Richter, André Werner, Nicole Werner, Dörte Radke, Alexander Teumer, Till Ittermann, Birgit Schauer, Vivien Henck, Nele Friedrich, Anke Hannemann, Theresa Winter, Matthias Nauck, Marcus Dörr, Martin Bahls, Stephan B Felix, Beate Stubbe, Ralf Ewert, Fabian Frost, Markus M Lerch, Hans J Grabe, Robin Bülow, Markus Otto, Norbert Hosten, Wolfgang Rathmann, Ulf Schminke, Rico Großjohann, Frank Tost, Georg Homuth, Uwe Völker, Stefan Weiss, Silva Holtfreter, Barbara M Bröker, Kathrin Zimmermann, Lars Kaderali, Marc Winnefeld, Boris Kristof, Klaus Berger, Stefanie Samietz, Christian Schwahn, Birte Holtfreter, Reiner Biffar, Stefan Kindler, Katharina Wittfeld, Wolfgang Hoffmann, Thomas Kocher
Publikováno v:
International Journal of Epidemiology. 51:e372-e383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372bfa795b3dd547834ca58d89369c7f
https://doi.org/10.1093/ije/dyac034
https://doi.org/10.1093/ije/dyac034
Autor:
Lars Kaderali, Horst Wenck, Boris Kristof, Jörn Söhle, Marc Winnefeld, Nicholas Holzscheck, Elke Grönniger, Cassandra Falckenhayn, Stefan Gallinat
Publikováno v:
Aging (Albany NY)
In recent years, reports of non-linear regulations in age- and longevity-associated biological processes have been accumulating. Inspired by methodological advances in precision medicine involving the integrative analysis of multi-omics data, we soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1902be835b546c232db2556a96a826
https://doi.org/10.18632/aging.103499
https://doi.org/10.18632/aging.103499
Autor:
Frank Lyko, Marc Winnefeld, Lara Terstegen, Rainer Haas, Boris Kristof, Günter Raddatz, Manuel Rodríguez-Paredes, Lars Kaderali, Julian Gutekunst, Sabine Hagemann, Himanshu Manchanda, Felix Bormann, Horst Wenck
Publikováno v:
Aging Cell
Summary Epigenetic changes represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Age-related changes in DNA methylation at the genome scale have been termed ‘epigenetic drift’, but the defining fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dd881c1898cb3ef84c420ea3992be7
http://europepmc.org/articles/PMC4854925
http://europepmc.org/articles/PMC4854925