Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Boris Krichel"'
Autor:
Eli J. Larson, Melissa R. Pergande, Michelle E. Moss, Kalina J. Rossler, R. Kent Wenger, Boris Krichel, Harini Josyer, Jake A. Melby, David S. Roberts, Kyndalanne Pike, Zhuoxin Shi, Hsin-Ju Chan, Bridget Knight, Holden T. Rogers, Kyle A. Brown, Irene M. Ong, Kyowon Jeong, Michael Marty, Sean J. McIlwain, Ying Ge
Publikováno v:
bioRxiv
Native top-down proteomics (nTDP) integrates native mass spectrometry (nMS) with top-down proteomics (TDP) to provide comprehensive analysis of protein complexes together with proteoform identification and characterization. Despite significant advanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8300ef14755c70a9b454318bc69722fc
https://doi.org/10.1101/2023.01.02.522513
https://doi.org/10.1101/2023.01.02.522513
Autor:
M. Schwinzer, Faisal Hammad Mekky Koua, Ashwin Chari, J. Lieske, Maria Garcia-Alai, Gleb Bourenkov, Russell J. Cox, Salah Awel, W. Ewert, Dušan Turk, Luca Gelisio, N. Werner, Hévila Brognaro, J. Pletzer-Zelgert, Juraj Knoska, Arwen R. Pearson, D. Melo, Matthias Rarey, Ilona Dunkel, Boris Krichel, Y. Gevorkov, A. Tolstikova, David von Stetten, Eike C. Schulz, Andrea Zaliani, Winfried Hinrichs, F. Trost, Helen M. Ginn, Xinyuanyuan Sun, Stephan Niebling, Holger Fleckenstein, Aleksandra Usenik, J. Wollenhaupt, Robin Schubert, Stephan Günther, Kristina Lorenzen, J. Boger, P. Reinke, Diana C. F. Monteiro, Bruno Alves Franca, Isabel Bento, Manfred S. Weiss, Ariana Peck, Dominik Oberthuer, Pedram Mehrabi, Pontus Fischer, Sebastian Günther, Jure Loboda, P. Lourdu Xavier, C. Schmidt, Christian Betzel, Huijong Han, N. Ullah, Philip Gribbon, Aida Rahmani Mashhour, Charlotte Uetrecht, Guillaume Pompidor, Christiane Ehrt, Christian G. Feiler, Saravanan Panneerselvam, Bernhard Ellinger, Christian M. Günther, Thomas J. Lane, Linlin Zhang, S. Meier, Tobias Beck, Henry N. Chapman, M. Domaracky, Sven Falke, Katarina Karničar, Markus Wolf, Cromarte Rogers, S. Saouane, Ivars Karpics, Rolf Hilgenfeld, Gisel E. Peña-Murillo, Vasundara Srinivasan, Alke Meents, Miriam Barthelmess, M. Galchenkova, B. Seychell, Beatriz Escudero-Pérez, Thomas A. White, Janine-Denise Kopicki, Joanna J. Zaitseva-Doyle, W. Brehm, M. Groessler, Brenna Norton-Baker, Frank Schlünzen, Chufeng Li, Henning Tidow, Maria Kuzikov, Andrea R. Beccari, Johanna Hakanpää, Henry Gieseler, Yaiza Fernández-García, Oleksandr Yefanov, Thomas R. Schneider, Anna Hänle, Jan Meyer, H. Andaleeb, V. Hennicke
Publikováno v:
Science (New York, N.y.)
Science 372 (6542): 642-646 (2021-05-07)
Science
Science / Science now 372(6542), 642-646 (2021). doi:10.1126/science.abf7945
Science 372 (6542): 642-646 (2021-05-07)
Science
Science / Science now 372(6542), 642-646 (2021). doi:10.1126/science.abf7945
A large-scale screen to target SARS-CoV-2 The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome is initially expressed as two large polyproteins. Its main protease, Mpro, is essential to yield functional viral proteins, making it a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7f9ac410aabd144f9e9014ed83aff5
https://resolver.caltech.edu/CaltechAUTHORS:20201113-100151878
https://resolver.caltech.edu/CaltechAUTHORS:20201113-100151878
Autor:
Dmitri I. Svergun, John Ziebuhr, Kristina Lorenzen, Boris Krichel, Renato Zenobi, Martin Koehler, Clement E. Blanchet, Robin Schubert, Charlotte Uetrecht, Ramakanth Madhugiri, L. Brings, Ganesh Bylapudi, C. Schmidt
Publikováno v:
Science Advances, 7 (10)
Science Advances
bioRxiv
article-version (status) pre
article-version (number) 2
Science advances 7(10), eabf1004 (1-15) (2021). doi:10.1126/sciadv.abf1004
Science Advances
bioRxiv
article-version (status) pre
article-version (number) 2
Science advances 7(10), eabf1004 (1-15) (2021). doi:10.1126/sciadv.abf1004
Coronaviral nsp7+8 complexes follow species- and stoichiometry-specific assembly pathways determined by few amino acid changes.
Coronaviruses infect many different species including humans. The last two decades have seen three zoonotic coronavir
Coronaviruses infect many different species including humans. The last two decades have seen three zoonotic coronavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c368da939228739887e5639c8f871ea8
https://hdl.handle.net/20.500.11850/474238
https://hdl.handle.net/20.500.11850/474238
Autor:
Henry Gieseler, David von Stetten, A. Tolstikova, Luca Gelisio, Yaiza Fernández-García, Guillaume Pompidor, Saravanan Panneerselvam, Cromarte Rogers, M. Galchenkova, Juraj Knoska, B. Seychell, Gleb Bourenkov, Ariana Peck, Stephan Niebling, D. Melo, Hévila Brognaro, Russell J. Cox, Rolf Hilgenfeld, W. Brehm, J. Lieske, Matthias Rarey, Aleksandra Usenik, Tobias Beck, Oleksandr Yefanov, Henry N. Chapman, Isabel Bento, C. Schmidt, M. Groessler, Ashwin Chari, Sven Falke, Katarina Karničar, Thomas J. Lane, Beatriz Escudero-Pérez, J. Boger, Bernhard Ellinger, Christian M. Günther, Christiane Ehrt, Markus Wolf, Jure Loboda, Thomas R. Schneider, Andrea Zaliani, P. Lourdu Xavier, Eike C. Schulz, J. Wollenhaupt, Brenna Norton-Baker, Ivars Karpics, Salah Awel, Aida Rahmani Mashhour, Frank Schlünzen, Chufeng Li, Henning Tidow, Robin Schubert, Y. Gevorkov, H. Andaleeb, P. Reinke, Stephan Günther, Christian G. Feiler, Manfred S. Weiss, Jo J. Zaitsev-Doyle, N. Ullah, M. Domaracky, Pontus Fischer, Linlin Zhang, Maria Kuzikov, V. Hennicke, W. Ewert, Faisal Hammad Mekky Koua, P. Gribbon, Xinyuanyuan Sun, Dominik Oberthuer, S. Meier, J. Pletzer-Zelgert, Kristina Lorenzen, Christian Betzel, M. Schwinzer, Bruno Alves Franca, Charlotte Uetrecht, S. Saouane, Pedram Mehrabi, Helen M. Ginn, Andrea R. Beccari, Johanna Hakanpää, Diana C. F. Monteiro, Ilona Dunkel, Janine-Denise Kopicki, Anna Hänle, Miriam Barthelmess, Jan Meyer, Dušan Turk, N. Werner, Thomas A. White, Boris Krichel, Winfried Hinrichs, F. Trost, Sebastian Günther, Filip Guicking, Vasundara Srinivasan, Alke Meents, Gisel E. Peña Murillo, Maria Marta Garcia Alai, Huijong Han, Arwen R. Pearson, Holger Fleckenstein
The coronavirus disease (COVID-19) caused by SARS-CoV-2 is creating tremendous health problems and economical challenges for mankind. To date, no effective drug is available to directly treat the disease and prevent virus spreading. In a search for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d640669dec95efad943e6c0a02e329
https://doi.org/10.1101/2020.11.12.378422
https://doi.org/10.1101/2020.11.12.378422
Autor:
Yaiza Fernández-García, Dominik Oberthuer, Christian Betzel, Tobias Beck, Markus Wolf, Kristina Lorenzen, M. Domaracky, Bruno Alves Franca, Jo J. Zaitsev-Doyle, Dušan Turk, Hévila Brognaro, Arwen R. Pearson, Henry N. Chapman, Jan Meyer, Robin Schubert, Stephan Günther, M. Galchenkova, Eike C. Schulz, B. Seychell, Manfred S. Weiss, H. Andaleeb, Aida Rahmani Mashhour, Y. Gevorkov, Sven Falke, Pedram Mehrabi, V. Hennicke, Beatriz Escudero-Pérez, Xinyuanyuan Sun, Juraj Knoska, Linlin Zhang, S. Meier, J. Pletzer-Zelgert, Holger Fleckenstein, N. Ullah, Rolf Hilgenfeld, Oleksandr Yefanov, Cromarte Rogers, Henry Gieseler, Thomas J. Lane, Ariana Peck, Alke Meents, C. Schmidt, J. Wollenhaupt, J. Lieske, Huijong Han, Helen M. Ginn, Bernhard Ellinger, Diana C. F. Monteiro, Christiane Ehrt, Pontus Fischer, Illona Dunkel, F. Trost, Luca Gelisio, Sebastian Günther, A. Tolstikova, Faisal Hammad Mekky Koua, Gisel Esperanza, D. Melo, Christian G. Feiler, Matthias Rarey, Andrea Zaliani, P. Reinke, M. Schwinzer, Russell J. Cox, Heshmat Noei, Salah Awel, N. Werner, Boris Krichel, Charlotte Uetrecht, Ashwin Chari, P. Gribbon, P. Lourdu Xavier, W. Brehm, S. Saouane, M. Groessler, Brenna Norton-Baker, Frank Schlünzen, Chufeng Li, Henning Tidow, Maria Kuzikov, Johanna Hakanpää, Miriam Barthelmess, Thomas A. White, Filip Guicking
Publikováno v:
Zenodo (2020). doi:10.1101/2020.05.02.043554
Here we present the crystal structure of SARS-CoV-2 main protease (Mpro) covalently bound to 2-methyl-1-tetralone. This complex was obtained by co-crystallization of Mpro with HEAT (2-(((4-hydroxyphenethyl)amino)methyl)-3,4-dihydronaphthalen-1(2H)-on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad748548ca306603280bbd7e9f68a2fe
https://hdl.handle.net/21.11116/0000-0006-61B1-421.11116/0000-0006-61B3-2
https://hdl.handle.net/21.11116/0000-0006-61B1-421.11116/0000-0006-61B3-2
Publikováno v:
Biochemical Journal
The biochemical journal / Reviews 477(5), 1009-1019 (2020). doi:10.1042/BCJ20200029
The biochemical journal / Reviews 477(5), 1009-1019 (2020). doi:10.1042/BCJ20200029
The biochemical journal / Reviews 477(5), 1009 - 1019 (2020). doi:10.1042/BCJ20200029
Severe acute respiratory syndrome coronavirus is the causative agent of a respiratory disease with a high case fatality rate. During the formation of the coron
Severe acute respiratory syndrome coronavirus is the causative agent of a respiratory disease with a high case fatality rate. During the formation of the coron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafe59cbb764b16d64884926436a1159
Publikováno v:
BIOspektrum. 24:164-167
In native mass spectrometry sample handling and measuring conditions are optimized to retain non-covalent interactions, allowing the detailed analysis of protein-protein and protein-ligand interactions. Thereby, stoichiometry, structure and dynamics
Publikováno v:
Complementary Strategies to Understand Virus Structure and Function
Advances in Virus Research
Advances in Virus Research-Complementary Strategies to Understand Virus Structure and Function
Advances in Virus Research
Advances in Virus Research-Complementary Strategies to Understand Virus Structure and Function
Over the last 20 years, mass spectrometry (MS), with its ability to analyze small sample amounts with high speed and sensitivity, has more and more entered the field of structural virology, aiming to investigate the structure and dynamics of viral pr
Autor:
Marcel Kwiatkowski, Eileen Magbanua, Kristina Szameit, Martin Zacharias, Ulrich Hahn, Hartmut Schlüter, Kira Schamoni, Katharina Berg, Erica Valentini, Dmitri I. Svergun, Isaure Chauvot de Beauchêne, Sven Kruspe, Boris Krichel, Charlotte Uetrecht
Publikováno v:
RNA Biology
RNA Biology, Taylor & Francis, 2016, 13 (10), pp.973-987. ⟨10.1080/15476286.2016.1212151⟩
RNA Biology, Taylor & Francis, 2016, 13 (10), pp.973-987. ⟨10.1080/15476286.2016.1212151⟩
International audience; G-quadruplexes have recently moved into focus of research in nucleic acids, thereby evolving in scientific significance from exceptional secondary structure motifs to complex modulators of gene regulation. Aptamers (nucleic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8b0e5fd56f6ad86c5e301dbf6ed2c7
https://hal.archives-ouvertes.fr/hal-01505860
https://hal.archives-ouvertes.fr/hal-01505860
Autor:
Rob Meijers, Arjan Narbad, Jeroen Krijgsveld, Sonia Garde, Haydyn D. T. Mertens, Andrew J. Thompson, Natalia Gómez-Torres, Boris Krichel, Dmitri I. Svergun, Stefan Leicht, Charlotte Uetrecht, Melinda J. Mayer, Matthew Dunne
Publikováno v:
Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
Europe PubMed Central
The Journal of Biological Chemistry
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
Europe PubMed Central
The Journal of Biological Chemistry
Bacteriophages produce endolysins, which lyse the bacterial host cell to release newly produced virions. The timing of lysis is regulated and is thought to involve the activation of a molecular switch. We present a crystal structure of the activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1310c3a91f0204fa0ba38e4d044a2d