Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Boris Juelg"'
Autor:
Vicky Roy, Wonyeong Jung, Caitlyn Linde, Emily Coates, Julie Ledgerwood, Pamela Costner, Galina Yamshchikov, Hendrik Streeck, Boris Juelg, Douglas A. Lauffenburger, Galit Alter
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Gardasil® (Merck) and Cervarix® (GlaxoSmithKline) both provide protection against infection with Human Papillomavirus 16 (HPV16) and Human Papillomavirus 18 (HPV18), that account for around 70% of cervical cancers. Both vaccines have been
Externí odkaz:
https://doaj.org/article/7cd3ff6b9e2a43718fe51f5ff9ac2cdf
Autor:
Maria Hottelet Foley, Talitha Forcier, Elizabeth McAndrew, Michael Gonzalez, Huabiao Chen, Boris Juelg, Bruce D Walker, Darrell J Irvine
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87873 (2014)
The dissemination of HIV from an initial site of infection is facilitated by motile HIV-infected CD4(+) T-cells. However, the impact of infected target cell migration on antigen recognition by HIV-specific CD8(+) T-cells is unclear. Using a 3D in vit
Externí odkaz:
https://doaj.org/article/e08fc7ea97d04f8191676c64c39adc4a
Autor:
Elissa K. Leonard, Miguel Aller Pellitero, Boris Juelg, Jamie B. Spangler, Netzahualcóyotl Arroyo-Currás
Publikováno v:
Journal of the American Chemical Society. 144:11226-11237
Rapid diagnostics that can accurately inform patients of disease risk and protection are critical to mitigating the spread of the current COVID-19 pandemic and future infectious disease outbreaks. To be effective, such diagnostics must rely on simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96aed14f66b8bd573697a2b61602ce2
https://doi.org/10.1021/jacs.2c02537
https://doi.org/10.1021/jacs.2c02537
Autor:
Ramy H Elshaboury, Meagan L Adamsick, Joanne Huang, Marisa Winkler, Musie Ghebremichael, Fiona Cheung, Bryan Polsonetti, Essy Mozaffari, Linda Chen, Boris Juelg, Elizabeth Hohmann
Publikováno v:
Open Forum Infectious Diseases. 9
Background Remdesivir (RDV) has been a mainstay of COVID-19 therapy for hospitalized patients. Impact of RDV timing in relationship to symptom-onset in hospitalized patients remains unclear, though early treatment is theorized to improve antiviral ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67a5dfa2db24af102cb19d7f587860cb
https://doi.org/10.1093/ofid/ofac492.993
https://doi.org/10.1093/ofid/ofac492.993
Autor:
Jonathan D. Herman, Chuangqi Wang, John Stephen Burke, Yonatan Zur, Hacheming Compere, Jaewon Kang, Ryan Macvicar, Sally Shin, Ian Frank, Don Siegel, Pablo Tebas, Grace H. Choi, Pamela A. Shaw, Hyunah Yoon, Liise-anne Pirofski, Boris Juelg, Katharine J. Bar, Douglas Lauffenburger, Galit Alter
Publikováno v:
SSRN Electronic Journal.
SummaryCOVID-19 convalescent plasma (CCP), a passive polyclonal antibody therapeutic, has exhibited mixed results in the treatment of COVID-19. Given that the therapeutic effect of CCP may extend beyond the ability of SARS-CoV-2-specific antibody bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e910988fba073d52b1532e008356c72b
https://doi.org/10.2139/ssrn.4052956
https://doi.org/10.2139/ssrn.4052956
This chapter covers the HIV reservoir and cure and remission strategies. It details the importance of why we should try to cure HIV and includes clinical observations where the concept of a “functional cure” has been introduced. Early establishme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5ced60c63e76f6a9755c1f0b18e3a61
https://doi.org/10.1093/med/9780197576595.003.0026
https://doi.org/10.1093/med/9780197576595.003.0026
Autor:
Galit Alter, Boris Juelg, Patrick H. Martin, Douglas A. Lauffenburger, Aaron G. Schmidt, Yannic C. Bartsch, Radoslow Nowak, Ching-Lin Hsieh, Kathryn Bowman, Marcia B. Goldberg, Jared Feldman, Stephanie Fischinger, Jason S McLellan, Jaewon Kang, Paulina Kaplonek, Chuangqi Wang, Matthew J. Gorman, Nir Hacohen, Michael R. Filbin, Diana Dayal, Elon R. Musk, Anil S. Menon, Eric S. Fischer
Publikováno v:
bioRxiv : the preprint server for biology.
The introduction of vaccines has inspired new hope in the battle against SARS-CoV-2. However, the emergence of viral variants, in the absence of potent antivirals, has left the world struggling with the uncertain nature of this disease. Antibodies cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bab017e8d83129c307140da252074d
https://pubmed.ncbi.nlm.nih.gov/34652962
https://pubmed.ncbi.nlm.nih.gov/34652962
Autor:
Junrui Lin, Duane R. Wesemann, Stephanie Fischinger, Boris Juelg, John R. Desjarlais, Anthony Griffiths, Natalia Kuzmina, Alexander Bukreyev, Matthew D. Slein, Ralph S. Baric, Rebecca I. Johnson, Adam Zuiani, Chad E. Mire, Alexandra Schäfer, Todd J. Suscovich, Nadia Storm, Caitlyn Linde, Anna N. Honko, Matthew J. Bernett, Pei Tong, John F. Burke, Jaap Goudsmit, Teng Zuo, Caroline Atyeo, Galit Alter, Sarah R. Leist
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
JCI Insight
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coupled with a lack of therapeutics, has paralyzed the globe. Although significant effort has been invested in identifying antibodies that block infection, the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59583ca9e74effc29953c9338825745
Autor:
Boris Juelg, Rajesh Gandhi
Publikováno v:
Fundamentals of HIV Medicine 2019
Upon completion of this chapter, the reader should be able to • Identify key hurdles for HIV eradication strategies and explain how the “Kick and Kill” approaches might overcome these challenges. Identify key hurdles for HIV eradication strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b3e5af98e5fe29bb04b1408630ff513
https://doi.org/10.1093/med/9780190942496.003.0006
https://doi.org/10.1093/med/9780190942496.003.0006
Autor:
Boris Juelg, Rajesh Gandhi
Although current antiretroviral therapy (ART) is highly effective at controlling HIV-1 replication, it does not eradicate or cure the infection. HIV-1 persists quiescently in cellular reservoirs, not detected by the immune system due to the lack of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b5594ea00314e7a57e35e429890dbc1
https://doi.org/10.1093/med/9780190493097.003.0006
https://doi.org/10.1093/med/9780190493097.003.0006