Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Boris J. Cheskis"'
Autor:
Su Jane Rutledge, James G. Greger, Boris J. Cheskis, Neil Cooch, Sunil Nagpal, Leonard P. Freedman, Christopher McNally, Sean McLarney, Belew Mekonnen, Diane Hauze, Ho-Sun Lam
Publikováno v:
Steroids. 73:901-905
Estrogens play a critical role in the regulation of cellular proliferation, differentiation, and apoptosis. Evidence indicates that this regulation is mediated by a complex interface of direct control of gene expression (so-called “genomic action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c272d5fccbdf5d97a7548612222e62ec
https://doi.org/10.1016/j.steroids.2007.12.028
https://doi.org/10.1016/j.steroids.2007.12.028
Publikováno v:
Journal of Cellular Physiology. 213:610-617
By regulating activities and expression levels of key signaling molecules, estrogens control mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen receptor (ER) leads to conformational changes that regulate the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61242128dff6622a6881f85b75968a27
https://doi.org/10.1002/jcp.21253
https://doi.org/10.1002/jcp.21253
Autor:
Boris J. Cheskis
Publikováno v:
Journal of Cellular Biochemistry. 93:20-27
Steroid hormones control a wide variety of cellular functions important for cell homeostasis, proliferation, differentiation, and apoptosis. Evidence collected in the last few years indicates that this regulation is mediated by a complex interface of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9e68952103170778a989f45257ade3
https://doi.org/10.1002/jcb.20180
https://doi.org/10.1002/jcb.20180
Publikováno v:
Biochemistry. 40:6756-6765
Analysis of estrogen receptor alpha and beta interplay with other transcription factors is critical to the understanding of how small molecules, the cognate ligands for these receptors, selectively regulate the mode and amplitude of gene transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2b1459b214313e9f9524eb789e6f9c
https://doi.org/10.1021/bi010379h
https://doi.org/10.1021/bi010379h
Autor:
Boris J. Cheskis, Leonard P. Freedman
Publikováno v:
Biochemistry. 35:3309-3318
Many nuclear hormone receptors, including the human 1,25-dihydroxyvitamin D3 receptor (VDR), bind cooperatively to DNA as either homodimers or heterodimers with the 9-cis-retinoic acid receptor (RXR). Protein-protein interactions mediated by residues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d02187de14d2448b03718fdc175be52
https://doi.org/10.1021/bi952283r
https://doi.org/10.1021/bi952283r
Autor:
Boris J. Cheskis, Leonard P. Freedman
Publikováno v:
Molecular and Cellular Biology. 14:3329-3338
Protein dimerization facilitates cooperative, high-affinity interactions with DNA. Nuclear hormone receptors, for example, bind either as homodimers or as heterodimers with retinoid X receptors (RXR) to half-site repeats that are stabilized by protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c17a6fe638d97e950dea980ad7bff2
https://doi.org/10.1128/mcb.14.5.3329-3338.1994
https://doi.org/10.1128/mcb.14.5.3329-3338.1994
Publikováno v:
Osteoporosis ISBN: 9780123705440
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169d92a88c7dd089d0ca7500f16ff64f
https://doi.org/10.1016/b978-012370544-0.50016-1
https://doi.org/10.1016/b978-012370544-0.50016-1
Autor:
Michael A. Mancini, Lori Sherman, Boris J. Cheskis, Dean P. Edwards, Viroj Boonyaratanakornkit, Eileen M. McGowan
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 21(2)
Human progesterone receptor (PR) contains a motif that interacts with the SH3 domain of Src and mediates rapid activation of Src and downstream MAPK (Erk-1/-2) without relying on the transcriptional activity of the receptor. Here we investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a19ff8ec042636121b12d021e7ab66
https://pubmed.ncbi.nlm.nih.gov/17138644
https://pubmed.ncbi.nlm.nih.gov/17138644
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 7(10)
1alpha,25-Dihydroxyvitamin D3 (1,25-(OH)2D3), the biologically active metabolite of vitamin D, mediates its actions via the vitamin D receptor (VDR), a member of the superfamily of steroid/thyroid hormone/retinoid receptors. 1,25-(OH)2D3 is required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::566c780ffb28b7124cd047afe6ab78cd
https://pubmed.ncbi.nlm.nih.gov/17086935
https://pubmed.ncbi.nlm.nih.gov/17086935
Publikováno v:
Steroids. 71(4)
We have previously demonstrated that modulator of nongenomic action of estrogen receptor (MNAR) integrates action of estrogen receptor alpha (ERα), and potentially some other nuclear receptors (NRs), in regulation of Src/Ras/Raf/mitogen-activated pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaeae4d655d700946e1b9e3789fdb11
https://pubmed.ncbi.nlm.nih.gov/16297421
https://pubmed.ncbi.nlm.nih.gov/16297421