Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Boris Görg"'
Autor:
Chaohui Lin, Edmund Osei Kuffour, Nina V. Fuchs, Christoph G.W. Gertzen, Jesko Kaiser, Maximilian Hirschenberger, Xiao Tang, Haifeng C. Xu, Oliver Michel, Ronny Tao, Alexandra Haase, Ulrich Martin, Thomas Kurz, Ingo Drexler, Boris Görg, Philipp A. Lang, Tom Luedde, Konstantin M.J. Sparrer, Holger Gohlke, Renate König, Carsten Münk
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113277- (2023)
Summary: Sensing of human immunodeficiency virus type 1 (HIV-1) DNA is mediated by the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling axis. Signal transduction and regulation of this cascade is achieved by post-translat
Externí odkaz:
https://doaj.org/article/a3e194c999a94c19ad46494fc14d84d4
Autor:
Steffen Pfeuffer, Thomas Müntefering, Leoni Rolfes, Frederike Anne Straeten, Susann Eichler, Joel Gruchot, Vera Dobelmann, Tim Prozorovski, Boris Görg, Mihael Vucur, Carsten Berndt, Patrick Küry, Tobias Ruck, Stefan Bittner, Dominik Bettenworth, Thomas Budde, Tom Lüdde, Sven G. Meuth
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 14, Iss 6, Pp 1199-1211 (2022)
Background & Aims: The 2-pore potassium channel subfamily K member 9 (KCNK9) regulates intracellular calcium concentration and thus modulates cell survival and inflammatory signaling pathways. It also was recognized as a risk allele for inflammatory
Externí odkaz:
https://doaj.org/article/66d58bba624540439c1c629a7cb0c453
Autor:
Nils Bardeck, Martha Paluschinski, Mirco Castoldi, Claus Kordes, Boris Görg, Jan Stindt, Tom Luedde, Stephan vom Dahl, Dieter Häussinger, David Schöler
Publikováno v:
JHEP Reports, Vol 4, Iss 4, Pp 100440- (2022)
Background & Aims: MicroRNAs (miRNAs) act as a regulatory mechanism on a post-transcriptional level by repressing gene transcription/translation and play a central role in the cellular stress response. Osmotic changes occur in a variety of diseases i
Externí odkaz:
https://doaj.org/article/e2c23718960f495d9d5937af1feca7bc
Autor:
Kaihui Lu, Marcel Zimmermann, Boris Görg, Hans-Jürgen Bidmon, Barbara Biermann, Nikolaj Klöcker, Dieter Häussinger, Andreas S. Reichert
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 539-553 (2019)
Background: Hepatic encephalopathy (HE) is a severe neuropsychiatric syndrome caused by various types of liver failure resulting in hyperammonemia-induced dysfunction of astrocytes. It is unclear whether autophagy, an important pro-survival pathway,
Externí odkaz:
https://doaj.org/article/987a8e5b53d54a558a3db58c8236f235
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 6, Pp 1427-1445 (2019)
Externí odkaz:
https://doaj.org/article/b2df231c5db7440cb7b83b260ac40900
Autor:
Vitaly I. Pozdeev, Elisabeth Lang, Boris Görg, Hans J. Bidmon, Prashant V. Shinde, Gerald Kircheis, Diran Herebian, Klaus Pfeffer, Florian Lang, Dieter Häussinger, Karl S. Lang, Philipp A. Lang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The devastating consequences of hepatic failure include hepatic encephalopathy, a severe, life threatening impairment of neuronal function. Hepatic encephalopathy is caused by impaired hepatic clearance of NH4 +. Cellular NH4 + uptake is acc
Externí odkaz:
https://doaj.org/article/ca0324e4a21046279b31b2b97c7642c2
Autor:
Niloufar Monhasery, Jens Moll, Carly Cuman, Manuel Franke, Larissa Lamertz, Rebecca Nitz, Boris Görg, Dieter Häussinger, Juliane Lokau, Doreen M. Floss, Roland Piekorz, Eva Dimitriadis, Christoph Garbers, Jürgen Scheller
Publikováno v:
Cell Reports, Vol 16, Iss 4, Pp 1067-1081 (2016)
Interleukin (IL)-11 signaling is involved in various processes, including epithelial intestinal cell regeneration and embryo implantation. IL-11 signaling is initiated upon binding of IL-11 to IL-11R1 or IL-11R2, two IL-11α-receptor splice variants,
Externí odkaz:
https://doaj.org/article/5b4bef001d7b44ef9b5292a02f4bbbdc
Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies.
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 2, p e1004693 (2016)
Glutamine synthetase (GS) catalyzes ATP-dependent ligation of ammonia and glutamate to glutamine. Two mutations of human GS (R324C and R341C) were connected to congenital glutamine deficiency with severe brain malformations resulting in neonatal deat
Externí odkaz:
https://doaj.org/article/4b46dbd80bb24f2889bfcc00ebc4998b
Autor:
Dieter Häussinger, Radha K. Dhiman, Vicente Felipo, Boris Görg, Rajiv Jalan, Gerald Kircheis, Manuela Merli, Sara Montagnese, Manuel Romero-Gomez, Alfons Schnitzler, Simon D. Taylor-Robinson, Hendrik Vilstrup
Publikováno v:
Häussinger, D, Dhiman, R K, Felipo, V, Görg, B, Jalan, R, Kircheis, G, Merli, M, Montagnese, S, Romero-Gomez, M, Schnitzler, A, Taylor-Robinson, S D & Vilstrup, H 2022, ' Hepatic encephalopathy ', Nature reviews. Disease primers, vol. 8, no. 43 . https://doi.org/10.1038/s41572-022-00366-6
Nature Reviews Disease Primers
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
Nature Reviews Disease Primers
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
Hepatic encephalopathy (HE) is a prognostically relevant neuropsychiatric syndrome that occurs in the course of acute or chronic liver disease. Besides ascites and variceal bleeding, it is the most serious complication of decompensated liver cirrhosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2249e44ea874f99f75d710aa000af1e
https://pure.au.dk/portal/da/publications/hepatic-encephalopathy(751cbe4a-c1ad-4181-937c-3b13dff19377).html
https://pure.au.dk/portal/da/publications/hepatic-encephalopathy(751cbe4a-c1ad-4181-937c-3b13dff19377).html
Autor:
Nils Bardeck, Martha Paluschinski, Mirco Castoldi, Claus Kordes, Boris Görg, Jan Stindt, Tom Luedde, Stephan vom Dahl, Dieter Häussinger, David Schöler
Publikováno v:
JHEP reports : innovation in hepatology. 4(4)
MicroRNAs (miRNAs) act as a regulatory mechanism on a post-transcriptional level by repressing gene transcription/translation and play a central role in the cellular stress response. Osmotic changes occur in a variety of diseases including liver cirr