Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Boris Feinstein"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1639(3):159-168
Microtubule-associated protein tau contains a consensus motif for protein kinase B/Akt (Akt), which plays an essential role in anti-apoptotic signaling. The motif encompasses the AT100 double phospho-epitope (Thr212/Ser214), a specific marker for Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd2582a257cdd2eb192801aa66567e8
Autor:
Yi Wen, John LaFrancois, Mark P. Burns, Boris Feinstein, Wendy Noble, Karen Duff, Vicki Olm, Lili Wang, Kate Gaynor, Pavan Krishnamurthy, Ratan Bhat, Jada Lewis, Dennis W. Dickson, Farhana Suleman, Cindy Zehr, Jordana L Meyerson, Emmanuel Planel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(19)
Neurofibrillary tangles composed of hyperphosphorylated, aggregated tau are a common pathological feature of tauopathies, including Alzheimer's disease. Abnormal phosphorylation of tau by kinases or phosphatases has been proposed as a pathogenic mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25842cdc9062a3d460c811e97b22364b
https://pubmed.ncbi.nlm.nih.gov/15867159
https://pubmed.ncbi.nlm.nih.gov/15867159