Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Boris FERKO"'
Publikováno v:
Microbiology Independent Research Journal, Vol 11, Iss 1, Pp 70-79 (2024)
BACKGROUND: Current influenza vaccines primarily elicit strain-specific immunity, providing limited protection against heterologous influenza strains. OBJECTIVE: This study aimed to develop a novel live attenuated influenza vaccine candidate with enh
Externí odkaz:
https://doaj.org/article/4430cec58bcf4a5e9afa2eb5ea12f5ac
Autor:
Christoph Jindra, Bettina Huber, Saeed Shafti-Keramat, Markus Wolschek, Boris Ferko, Thomas Muster, Sabine Brandt, Reinhard Kirnbauer
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138722 (2015)
Persistent infection with high-risk human papillomavirus (HPV) types, most often HPV16 and HPV18, causes all cervical and most anal cancers, and a subset of vulvar, vaginal, penile and oropharyngeal carcinomas. Two prophylactic virus-like particle (V
Externí odkaz:
https://doaj.org/article/cc9a5bc4b1a546f48ac8593e1eb1e405
Autor:
Christoph Jindra, Bettina Huber, Saeed Shafti-Keramat, Markus Wolschek, Boris Ferko, Thomas Muster, Sabine Brandt, Reinhard Kirnbauer
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143269 (2015)
Externí odkaz:
https://doaj.org/article/b2f2bac9cddb4de6a49b8de051100c90
Autor:
Hae-Jung Park, Boris Ferko, Young-Ho Byun, Joo-Hye Song, Gye-Yeong Han, Elisabeth Roethl, Andrej Egorov, Thomas Muster, Baiklin Seong, Mi-Na Kweon, Manki Song, Cecil Czerkinsky, Huan H Nguyen
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39921 (2012)
The nonstructural protein 1 (NS1) of influenza A virus (IAV) enables the virus to disarm the host cell type 1 IFN defense system. Mutation or deletion of the NS1 gene leads to attenuation of the virus and enhances host antiviral response making such
Externí odkaz:
https://doaj.org/article/b0511f0df3d7418ca52e1076f2754670
Autor:
Brigitte M Krenn, Andrej Egorov, Ekaterina Romanovskaya-Romanko, Markus Wolschek, Sabine Nakowitsch, Tanja Ruthsatz, Bettina Kiefmann, Alexander Morokutti, Johannes Humer, Janina Geiler, Jindrich Cinatl, Martin Michaelis, Nina Wressnigg, Sanda Sturlan, Boris Ferko, Oleg V Batishchev, Andrey V Indenbom, Rong Zhu, Markus Kastner, Peter Hinterdorfer, Oleg Kiselev, Thomas Muster, Julia Romanova
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18577 (2011)
BACKGROUND: H5N1 influenza vaccines, including live intranasal, appear to be relatively less immunogenic compared to seasonal analogs. The main influenza virus surface glycoprotein hemagglutinin (HA) of highly pathogenic avian influenza viruses (HPAI
Externí odkaz:
https://doaj.org/article/d9c2e3f4d7b94f30b4cd05496ba9f848
Autor:
Julia Romanova, Brigitte M Krenn, Markus Wolschek, Boris Ferko, Ekaterina Romanovskaja-Romanko, Alexander Morokutti, Anna-Polina Shurygina, Sabine Nakowitsch, Tanja Ruthsatz, Bettina Kiefmann, Ulrich König, Michael Bergmann, Monika Sachet, Shobana Balasingam, Alexander Mann, John Oxford, Martin Slais, Oleg Kiselev, Thomas Muster, Andrej Egorov
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5984 (2009)
BACKGROUND:We developed a novel intranasal influenza vaccine approach that is based on the construction of replication-deficient vaccine viruses that lack the entire NS1 gene (DeltaNS1 virus). We previously showed that these viruses undergo abortive
Externí odkaz:
https://doaj.org/article/b3e0973ffb1a4402a23935312dac8bf4
Autor:
Wolfgang Pohl, Helmut Schmutz, Andreas Renner, Katharina Marth, Philipp Badorrek, Julia Romanova, Boris Ferko, Meike Müller, Vladimir Nebolsin
Introduction XC8 (histamine glutarimide) is a novel agent which targets eosinophilic migration and mast cell degranulation and has shown anti-asthmatic effects in animal studies. Objective The objective of this placebo-controlled phase 1 study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231738f94ae11d04949c93dbdcadc897
http://hdl.handle.net/10138/323903
http://hdl.handle.net/10138/323903
Publikováno v:
Airway pharmacology and treatment.
XC8 (histamine glutarimide) is a non-steroidal anti-inflammatory anti-bronchoconstriction agent which targets eosinophilic migration and mast cell degranulation by inhibition of chemokines (CCL2, CCL7, CCL8, CCL13). Previous animal studies have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593fbd4065d3f1b2c3cd93452d116c72
https://doi.org/10.1183/13993003.congress-2019.pa3712
https://doi.org/10.1183/13993003.congress-2019.pa3712
Autor:
Helmut Schmutz, Tatyana Alexandrovna Kromova, Boris Ferko, Julia Romanova, Rydlovskaya Anastasia Vladimirovna, Oxana V Proskurina, Anna N Amelina, Vladimir Nebolsin, Andreas Renner
Publikováno v:
Current pharmaceutical biotechnology. 20(2)
Background:Corticosteroids are the preferred option to treat asthma, however, they possess serious side effects and are inefficient in 10% of patients. Thus, new therapeutic approaches for asthma treatment are required.Objective:To study the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7f14cdc063dca226c7d0b675e74d9e
https://pubmed.ncbi.nlm.nih.gov/30767739
https://pubmed.ncbi.nlm.nih.gov/30767739
Autor:
Janina Geiler, Joachim Seipelt, Thorsten Fuereder, Thomas Muster, Michael Kundi, Doris Hoeflmayer, Monika Redlberger-Fritz, Markus Wolschek, Volker Wacheck, Andrea Pfeiffer, Alexander Morokutti, Jindrich Cinatl, Julia Romanova, Rosmarie Dick-Gudenus, Christian A. Mueller, Andrej Egorov, Michael Bergmann, Elisabeth Roethl, Martin Michaelis, Franz Groiss, Therese Popow-Kraupp, Boris Ferko
Publikováno v:
The Journal of Infectious Diseases. 201:354-362
BACKGROUND. The nonstructural protein NS1 of influenza virus counteracts the interferon-mediated immune response of the host. By deleting the open reading frame of NS1, we have generated a novel type of influenza vaccine. We studied the safety and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d9ba66d2c39936b86589f617c6aa1d
https://doi.org/10.1086/649428
https://doi.org/10.1086/649428