Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Boris Decourt"'
Publikováno v:
Neurology and Therapy, Vol 13, Iss 6, Pp 1571-1595 (2024)
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder that significantly impairs cognitive and functional abilities, placing a substantial burden on both patients and caregivers. Current symptomatic treatments fail to halt the progressi
Externí odkaz:
https://doaj.org/article/a4870cfad92b4350b97da95764a25392
Publikováno v:
Neurology and Therapy, Vol 13, Iss 6, Pp 1541-1557 (2024)
Abstract As the prevalence of Alzheimer’s disease (AD) and its impact on healthcare systems increase, developing tools for accurate diagnosis and monitoring of disease progression is a priority. Recent technological advancements have allowed for th
Externí odkaz:
https://doaj.org/article/9c224d6e71524237be95fc28056caba9
Publikováno v:
Neurology and Therapy, Vol 13, Iss 4, Pp 975-1013 (2024)
Abstract Progressive supranuclear palsy (PSP) is a neurodegenerative disorder resulting from the deposition of misfolded and neurotoxic forms of tau protein in specific areas of the midbrain, basal ganglia, and cortex. It is one of the most represent
Externí odkaz:
https://doaj.org/article/944c2a5236c04191939d2533133670e7
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 99 (2024)
Type 2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD) are chronic, progressive disorders affecting the elderly, which fosters global healthcare concern with the growing aging population. Both T2DM and AD have been linked with increasing age,
Externí odkaz:
https://doaj.org/article/953e7ec9ca5c4d9daa03d492b4f5bcf2
Autor:
Kaviyon Sadrolashrafi, Suzanne Craft, Boris Decourt, Abdu Adem, Jeffrey R. Wilson, Justin Miller, Marwan N. Sabbagh
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction We examined the association between Alzheimer's disease (AD) and type 2 diabetes mellitus (DM) and hypothesized that diabetes is associated with an increased pathological burden in clinically and pathologically diagnosed AD. Met
Externí odkaz:
https://doaj.org/article/f8bc571c9a02422d88f95055adde81ec
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138a1e2ee256ad67307a41039aa246ba
https://doi.org/10.1002/alz.059716
https://doi.org/10.1002/alz.059716
Autor:
Marwan N. Sabbagh, Boris DeCourt
Publikováno v:
Nature Reviews Neurology. 19:71-72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee9adead6f7ccfce82da57a7b82c7e58
https://doi.org/10.1038/s41582-022-00767-x
https://doi.org/10.1038/s41582-022-00767-x
COR388 (atuzaginstat): an investigational gingipain inhibitor for the treatment of Alzheimer disease
Autor:
Marwan N. Sabbagh, Boris Decourt
Publikováno v:
Expert opinion on investigational drugs. 31(10)
Evidence from in vitro and in vivo studies demonstrates that amyloid beta (Aβ) oligomers have potent, broad-spectrum antimicrobial properties created by fibrils that entrap pathogens and disrupt their membranes. Data suggest that Aβ may play a prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed8680e86679bf6d04f5f17163679df
https://pubmed.ncbi.nlm.nih.gov/36003033
https://pubmed.ncbi.nlm.nih.gov/36003033
Autor:
Jiong Shi, Stephen E. Jones, Aaron Ritter, Justin B. Miller, Boris Decourt, Marwan N. Sabbagh, Dylan Wint
Publikováno v:
Journal of Alzheimer's Disease Reports
Background: Informant-based measures are effective screening tools for cognitive impairment. The Alzheimer’s Questionnaire (AQ) is a subjective, informant-based measure that detects amnestic mild cognitive impairment (aMCI) and Alzheimer’s diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacf17e1e4aad4844d41201162185462
https://doi.org/10.3233/adr-200260
https://doi.org/10.3233/adr-200260
Autor:
Christopher Dardis, Xiaowei Zhuang, Boris Decourt, Garam Lee, Jeffrey R. Wilson, Dietmar Cordes, Marwan N. Sabbagh, Katurah Hartley, Nadia D Fulkerson, Tessa St Rose, Aaron Ritter, Frank P. DiFilippo
Publikováno v:
Open access journal of clinical trials
With the general population reaching higher ages, a surge in Alzheimer's disease (AD) incidence will happen in the coming decades, putting a heavy burden on families and healthcare systems Worldwide. This emphasizes the pressing need for AD therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000514fe8b00e67356ff7420ca987183
http://europepmc.org/articles/PMC7051033
http://europepmc.org/articles/PMC7051033