Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Boris D. Zlatopolskiy"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15251 (2023)
Tryptophan (Trp) is an essential proteinogenic amino acid and metabolic precursor for several signaling molecules that has been implicated in many physiological and pathological processes. Since the two main branches of Trp metabolism—serotonin bio
Externí odkaz:
https://doaj.org/article/b02869e16ffa47169fcac007a2f44d86
Publikováno v:
Molecules, Vol 28, Iss 7, p 2890 (2023)
Gliomas are the most common primary brain tumors in adults. A diffuse infiltrative growth pattern and high resistance to therapy make them largely incurable, but there are significant differences in the prognosis of patients with different subtypes o
Externí odkaz:
https://doaj.org/article/7f3c9f571313473f9c29976ece79459c
Autor:
Heike Endepols, Boris D. Zlatopolskiy, Johannes Zischler, Nazanin Alavinejad, Nadine Apetz, Stefanie Vus, Alexander Drzezga, Bernd Neumaier
Publikováno v:
NeuroImage, Vol 247, Iss , Pp 118842- (2022)
Degradation products of the essential amino acid tryptophan (Trp) are important signaling molecules in the mammalian brain. Trp is metabolized either through the kynurenine pathway or enters serotonin and melatonin syntheses. The aim of the present w
Externí odkaz:
https://doaj.org/article/acd2ba9d9d0a41de89c91dae238e3ac9
Autor:
Melanie Hohberg, Carsten Kobe, Philipp Krapf, Philipp Täger, Jochen Hammes, Felix Dietlein, Boris D. Zlatopolskiy, Heike Endepols, Markus Wild, Stephan Neubauer, Axel Heidenreich, Bernd Neumaier, Alexander Drzezga, Markus Dietlein
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Aim We investigated the whole-body distribution and the radiation dosimetry of [18F]-JK-PSMA-7, a novel 18F-labeled PSMA-ligand for PET/CT imaging of prostate cancer. Methods Ten patients with prostate cancer and biochemical recurrence or ra
Externí odkaz:
https://doaj.org/article/a69f0d440c4d48738aee1058c47e055d
Autor:
Heike Endepols, Agnieszka Morgenroth, Boris D. Zlatopolskiy, Philipp Krapf, Johannes Zischler, Raphael Richarz, Sergio Muñoz Vásquez, Bernd Neumaier, Felix M. Mottaghy
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background The recent implementation of PET with prostate specific membrane antigen (PSMA)-specific radiotracers into the clinical practice has resulted in the significant improvement of accuracy in the detection of prostate carcinoma (PCa).
Externí odkaz:
https://doaj.org/article/471f273ba81d42d0b468c759a57c1b75
Autor:
Heike Endepols, Felix M. Mottaghy, Sakine Simsekyilmaz, Jan Bucerius, Felix Vogt, Oliver Winz, Raphael Richarz, Philipp Krapf, Bernd Neumaier, Boris D. Zlatopolskiy, Agnieszka Morgenroth
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract The short- and long-term success of intravascular stents depends on a proper re-endothelialisation after the intervention-induced endothelial denudation. The aim of this study was to evaluate the potential of in vivo molecular imaging of glu
Externí odkaz:
https://doaj.org/article/0ded07f50df94a769f2016a9245a7218
Autor:
Viktoriya V. Orlovskaya, Austin S. Craig, Olga S. Fedorova, Olga F. Kuznetsova, Bernd Neumaier, Raisa N. Krasikova, Boris D. Zlatopolskiy
Publikováno v:
Molecules, Vol 26, Iss 18, p 5550 (2021)
6-l-[18F]Fluoro-m-tyrosine (6-l-[18F]FMT) represents a valuable alternative to 6-l-[18F]FDOPA which is conventionally used for the diagnosis and staging of Parkinson’s disease. However, clinical applications of 6-l-[18F]FMT have been limited by the
Externí odkaz:
https://doaj.org/article/5752d86ea0fa4051a4a8486c56970e7d
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1542 (2021)
Delivery of most drugs into the central nervous system (CNS) is restricted by the blood–brain barrier (BBB), which remains a significant bottleneck for development of novel CNS-targeted therapeutics or molecular tracers for neuroimaging. Consistent
Externí odkaz:
https://doaj.org/article/d267c26f91fe4c81b07524201a53f9ae
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1247 (2020)
The emergence and global spread of COVID-19, an infectious disease caused by the novel coronavirus SARS-CoV-2, has resulted in a continuing pandemic threat to global health. Nuclear medicine techniques can be used for functional imaging of (patho)phy
Externí odkaz:
https://doaj.org/article/fa7bd79f89cb42f6a564347551a6635f
Autor:
Boris D. Zlatopolskiy, Felix Neumaier, Till Rüngeler, Birte Drewes, Niklas Kolks, Bernd Neumaier
Publikováno v:
Molecules, Vol 25, Iss 12, p 2880 (2020)
M1 muscarinic acetylcholine receptors (mAChRs) are abundant in postsynaptic nerve terminals of all forebrain regions and have been implicated in the cognitive decline associated with Alzheimer’s disease and other CNS pathologies. Consequently, majo
Externí odkaz:
https://doaj.org/article/601a7baf02da4c3c892d1c769490d6fc