Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Boris Arshava"'
Voltage-gated sodium channels are membrane proteins that play an important role in the propagation of electrical signals by mediating the rising phase of an action potential. Numerous diseases, including epilepsy, extreme pain, and certain cardiac ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba36386f8fecce5e953b1071a2c967ce
https://doi.org/10.1101/2021.05.21.443843
https://doi.org/10.1101/2021.05.21.443843
Publikováno v:
The FEBS Journal. 285:4296-4310
Infection by HIV-1 requires protein-protein interactions involving gp120, CD4 and CCR5. We have previously demonstrated that the transferred nuclear Overhauser effect (TRNOE), in combination with asymmetric deuteration of a protein and a peptide liga
Publikováno v:
Solid State Nuclear Magnetic Resonance. 94:1-6
The effects of various lipid bound paramagnetic metal ions on liposomes prepared in the presence of trehalose and chelator lipids are evaluated to observe site-specific signal changes on liposome samples with optimal resolution in solid-state NMR spe
Autor:
Fred Naider, Michael Levitt, João P. G. L. M. Rodrigues, Jacob Anglister, Gautam Srivastava, Meital Abayev, Mariusz Jaremko, Boris Arshava, Łukasz Jaremko
Publikováno v:
The FEBS Journal. 285:1988-2003
The inflammatory chemokine CCL5, which binds the chemokine receptor CCR5 in a two-step mechanism so as to activate signaling pathways in hematopoetic cells, plays an important role in immune surveillance, inflammation, and development as well as in s
Publikováno v:
Biophysical Journal. 120:153a-154a
Autor:
Gautam Srivastava, Sabine R. Akabayov, Fred Naider, Naama Kessler, Jacob Anglister, Adi Moseri, Boris Arshava
Publikováno v:
The FEBS Journal. 283:4084-4096
Weak protein-protein and protein-ligand interactions play important roles in biological recognition. In many cases, simplification of structural studies of large protein complexes is achieved by investigation of the interaction between the protein an
Autor:
Meital Abayev, Oren Tchaicheeyan, Jacob Anglister, Naama Kessler, Adi Moseri, Fred Naider, Tali Scherf, Boris Arshava
Publikováno v:
FEBS Journal. 282:1906-1921
C-C chemokine receptor 5 (CCR5) serves as a co-receptor for HIV-1. The CCR5 N-terminal segment, the second extracellular loop (ECL2) and the transmembrane helices have been implicated in binding the envelope glycoprotein gp120. Peptides corresponding
Autor:
Jeffrey M. Becker, Leah S. Cohen, Oliver Zerbe, Boris Arshava, Katrina E. Fracchiolla, Martin Poms, Fred Naider
Publikováno v:
Journal of Peptide Science. 21:212-222
This report summarizes recent biophysical and protein expression experiments on polypeptides containing the N-terminus, the first, second, and third transmembrane (TM) domains and the contiguous loops of the α-factor receptor Ste2p, a G protein-coup
Autor:
Katrina E, Fracchiolla, Leah S, Cohen, Boris, Arshava, Martin, Poms, Oliver, Zerbe, Jeffrey M, Becker, Fred, Naider
Publikováno v:
JOURNAL OF PEPTIDE SCIENCE
This report summarizes recent biophysical and protein expression experiments on polypeptides containing the N-terminus, the first, second, and third transmembrane (TM) domains and the contiguous loops of the α-factor receptor Ste2p, a G protein-coup
Autor:
Fa-Xiang Ding, Sarah Kauffman, Fred Naider, Leah S. Cohen, Katrina E. Fracchiolla, Boris Arshava, Jeffrey M. Becker, Elizabeth Mathew, Mark E. Dumont
Publikováno v:
Biopolymers. 102:16-29
Structural analysis by NMR of G protein-coupled receptors (GPCRs) has proven to be extremely challenging. To reduce the number of peaks in the NMR spectra by segmentally labeling a GPCR, we have developed a Guided Reconstitution method that includes