Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Boris, Striepen"'
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Infection with the apicomplexan parasite Cryptosporidium is a leading cause of diarrheal disease. Cryptosporidiosis is of particular importance in infants and shows a strong association with malnutrition, both as a risk factor and as a conse
Externí odkaz:
https://doaj.org/article/9590de29d671445582465bc47250772a
Autor:
Nicolas Dos Santos Pacheco, Albert Tell i Puig, Amandine Guérin, Matthew Martinez, Bohumil Maco, Nicolò Tosetti, Estefanía Delgado-Betancourt, Matteo Lunghi, Boris Striepen, Yi-Wei Chang, Dominique Soldati-Favre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract In Apicomplexa, rhoptry discharge is essential for invasion and involves an apical vesicle (AV) docking one or two rhoptries to a macromolecular secretory apparatus. Toxoplasma gondii is armed with 10–12 rhoptries and 5-6 microtubule-assoc
Externí odkaz:
https://doaj.org/article/db5a5f1efb7a45248abcc933162e7602
Autor:
Ryan D Pardy, Katelyn A Walzer, Bethan A Wallbank, Jessica H Byerly, Keenan M O'Dea, Ian S Cohn, Breanne E Haskins, Justin L Roncaioli, Eleanor J Smith, Gracyn Y Buenconsejo, Boris Striepen, Christopher A Hunter
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1011820 (2024)
The production of IFN-γ is crucial for control of multiple enteric infections, but its impact on intestinal epithelial cells (IEC) is not well understood. Cryptosporidium parasites exclusively infect epithelial cells and the ability of interferons t
Externí odkaz:
https://doaj.org/article/22da1c042a9b49efbdc01edf4adb722e
Autor:
Matthew Martinez, Shrawan Kumar Mageswaran, Amandine Guérin, William David Chen, Cameron Parker Thompson, Sabine Chavin, Dominique Soldati-Favre, Boris Striepen, Yi-Wei Chang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin motors that translocate host-attached surface adhesins along th
Externí odkaz:
https://doaj.org/article/13a350adc2704a6a8ba35bd0fb27a960
Autor:
Paul Kelly, William A Petri, Rashidul Haque, Ibrahim A Khalil, Lynn Barrett, Tom Kennedy, Timothy Wells, Christopher D Huston, James Platts-mills, Grace S Yang, Richard Omore, Ian H Gilbert, Sumiti Vinayak, Boris Striepen, Ujjini H Manjunatha, Wesley C Van Voorhis, Samuel L M Arnold, Beatriz Baragana, Frederick S Buckner, Jeremy D Burrows, Maria A Caravedo, Ryan Choi, Robert K M Choy, Eugenio de Hostos, Thierry Diagana, Suzanne Duce, Matthew A Hulverson, Pui-Ying Iroh Tam, Minju Kim, Poonum Korpe, Benoît Laleu, Diana Lalika, Fabrice Laurent, Case W McNamara, Marvin J Meyers, Roberta M O’Connor, Kayode K Ojo, Philipp Olias, Nede Ovbiebo, Mattie C Pawlowic, Gladys Queen, Divya Rao, Kevin Reed, Michael W Riggs, Jennifer L Roxas, Adam Sateriale, Deborah A Schaefer, L David Sibley, Jonathan M Spector, Chris Tonkin, Timilehin E Toye, Saul Tzipori, A Clinton White
Publikováno v:
BMJ Global Health, Vol 8, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/540e409047fd43baae051b1737c1bbc5
Autor:
Jayesh Tandel, Katelyn A. Walzer, Jessica H. Byerly, Brittain Pinkston, Daniel P. Beiting, Boris Striepen
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT The apicomplexan parasite Cryptosporidium is a leading global cause of diarrheal disease, and the infection poses a particularly grave threat to young children and those with weakened immune function. Infection occurs by ingestion of meiotic
Externí odkaz:
https://doaj.org/article/9fec4c31937d446991e446cf33744adf
Autor:
Shrawan Kumar Mageswaran, Amandine Guérin, Liam M. Theveny, William David Chen, Matthew Martinez, Maryse Lebrun, Boris Striepen, Yi-Wei Chang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The rhoptry is an apical secretory organelle of apicomplexan parasites that is essential for host cell invasion. Here, Mageswaran et al. provide in situ ultrastructures of rhoptries from two pathogens, revealing a conserved architecture including lum
Externí odkaz:
https://doaj.org/article/65277b58fe3c478dae8f5b0f288611d4
Autor:
Jan Pyrih, Vojtěch Žárský, Justin D. Fellows, Christopher Grosche, Dorota Wloga, Boris Striepen, Uwe G. Maier, Jan Tachezy
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Nbp35-like proteins (Nbp35, Cfd1, HCF101, Ind1, and AbpC) are P-loop NTPases that serve as components of iron-sulfur cluster (FeS) assembly machineries. In eukaryotes, Ind1 is present in mitochondria, and its function is associate
Externí odkaz:
https://doaj.org/article/614cb09431204a6ea3555c71870cddf4
Autor:
Alexis R Gibson, Adam Sateriale, Jennifer E Dumaine, Julie B Engiles, Ryan D Pardy, Jodi A Gullicksrud, Keenan M O'Dea, John G Doench, Daniel P Beiting, Christopher A Hunter, Boris Striepen
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010003 (2022)
Cryptosporidium is a leading cause of severe diarrhea and diarrheal-related death in children worldwide. As an obligate intracellular parasite, Cryptosporidium relies on intestinal epithelial cells to provide a niche for its growth and survival, but
Externí odkaz:
https://doaj.org/article/367de30753434b6e8aa16b952cf3306a
Publikováno v:
PLoS Biology, Vol 20, Iss 4 (2022)
Cryptosporidium is a leading infectious cause of diarrhea around the world associated with waterborne outbreaks, community spread, or zoonotic transmission. The parasite has significant impact on early childhood mortality, and infection is both a con
Externí odkaz:
https://doaj.org/article/a488c79bcf2d401f8810d596cef5e51f