Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Borhane, Guezguez"'
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/f8b0c33b4f3c4a62a0d15ea12f4f381c
Autor:
Kevin Legscha, Abdulkadir Yilmaz, Lea Märker, Edite Antunes, Catherine Wölfel, Borhane Guezguez, Stefan Porubsky, Matthias Theobald, Hakim Echchannaoui
Publikováno v:
HemaSphere, Vol 7, p e8611843 (2023)
Externí odkaz:
https://doaj.org/article/cea84d8dc580463d8f0319ceb272c352
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Transcutaneous immunization (TCI) utilizing the TLR7 agonist imiquimod (IMQ-TCI) induces T cell-driven protective immunity upon application onto intact skin. In our present work, we combine the anti-psoriatic agent dithranol with IMQ-TCI to
Externí odkaz:
https://doaj.org/article/7d6f5fd597ff43259826599506c19bbf
Autor:
Kevin Woods, Borhane Guezguez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mesenchymal stromal cells (MSCs) are a heterogenous cell population found in a wide range of tissues in the body, known for their nutrient-producing and immunomodulatory functions. In the bone marrow (BM), these MSCs are critical for the regulation o
Externí odkaz:
https://doaj.org/article/d3388cf26ad149e3b5c3557a7518b40f
Autor:
Jean-Christophe Bourdon, Kevin Jan Legscha, Edite Antunes Ferreira, Antonios Chamoun, Alexander Lang, Mohamed Hemaid Sayed Awwad, Gigi Nu Hoang Quy Ton, Danuta Galetzka, Borhane Guezguez, Michael Hundemer, Markus Munder, Matthias Theobald, Hakim Echchannaoui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Tumor microenvironment-associated T cell senescence is a key limiting factor for durable effective cancer immunotherapy. A few studies have demonstrated the critical role of the tumor suppressor TP53-derived p53 isoforms in cellular senesc
Externí odkaz:
https://doaj.org/article/92aec1eee98146ff8df8385a1b588618
Autor:
Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Benedict Schubert, Haiyang Yun, Sarah J Horton, Shuchi Agrawal-Singh, Patricia S Haehnel, Faisal Basheer, Dave Lugo, Michael WM Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Rab K Prinjha, Brian JP Huntly, Daniel Sasca
Initial clinical trials with drugs targeting epigenetic modulators - such as bromodomain and extraterminal (BET) inhibitors - demonstrate modest results in acute myeloid leukemia (AML). The main reason for this involves an increased transcriptional p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99d2692ba4e1ae6a1d89938b2c1a17d9
https://doi.org/10.1101/2022.09.14.507850
https://doi.org/10.1101/2022.09.14.507850
Publikováno v:
Current Opinion in Hematology. 28:356-363
Purpose of review Comprehensive sequencing studies aimed at determining the genetic landscape of myeloid neoplasms have identified epigenetic regulators to be among the most commonly mutated genes. Detailed studies have also revealed a number of epig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b598385cf4a1593c63f551cc501a60ea
https://doi.org/10.1097/moh.0000000000000673
https://doi.org/10.1097/moh.0000000000000673
Publikováno v:
Current opinion in hematology. 28(5)
Comprehensive sequencing studies aimed at determining the genetic landscape of myeloid neoplasms have identified epigenetic regulators to be among the most commonly mutated genes. Detailed studies have also revealed a number of epigenetic vulnerabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::260374e6bb36e6a94db967c250df62c4
https://pubmed.ncbi.nlm.nih.gov/34267079
https://pubmed.ncbi.nlm.nih.gov/34267079
Autor:
Borhane Guezguez
Publikováno v:
Current opinion in hematology. 28(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b7679349c98bbb5c6b6c5ea0d1591a
https://pubmed.ncbi.nlm.nih.gov/34261881
https://pubmed.ncbi.nlm.nih.gov/34261881
Autor:
Borhane Guezguez, Alexander Lang, Mohamed H.S. Awwad, Jean-Christophe Bourdon, Matthias Theobald, Edite Antunes Ferreira, Hakim Echchannaoui, Markus Munder, Kevin Jan Legscha, Danuta Galetzka, Gigi Nu Hoang Quy Ton, Michael Hundemer, Antonios Chamoun
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundTumor microenvironment-associated T cell senescence is a key limiting factor for durable effective cancer immunotherapy. A few studies have demonstrated the critical role of the tumor suppressor TP53-derived p53 isoforms in cellular senesce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abc0a82e7522f0090b689feb42cadd1
https://jitc.bmj.com/content/9/6/e001846.full
https://jitc.bmj.com/content/9/6/e001846.full