Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Borek Vojtesek"'
Autor:
Konstantinos Karakostis, Laurence Malbert-Colas, Aikaterini Thermou, Borek Vojtesek, Robin Fåhraeus
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background The ATM kinase constitutes a master regulatory hub of DNA damage and activates the p53 response pathway by phosphorylating the MDM2 protein, which develops an affinity for the p53 mRNA secondary structure. Disruption of this inter
Externí odkaz:
https://doaj.org/article/6c35679e66534f3596b761aa7d227558
Autor:
Ashita Singh, Monikaben Padariya, Jakub Faktor, Sachin Kote, Sara Mikac, Alicja Dziadosz, Tak W. Lam, Jack Brydon, Martin A. Wear, Kathryn L. Ball, Ted Hupp, Alicja Sznarkowska, Borek Vojtesek, Umesh Kalathiya
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The interferon signalling system elicits a robust cytokine response against a wide range of environmental pathogenic and internal pathological signals, leading to induction of a subset of interferon-induced proteins. We applied DSS (disuccin
Externí odkaz:
https://doaj.org/article/dde10cbfa9fa423d95fc9d4bcdeb1995
Autor:
Lucia Minoli, Luca Licenziato, Mikolaj Kocikowski, Marzia Cino, Katarzyna Dziubek, Selina Iussich, Antonella Fanelli, Emanuela Morello, Marina Martano, Ted Hupp, Borek Vojtesek, Maciej Parys, Luca Aresu
Publikováno v:
Cancers, Vol 14, Iss 24, p 6188 (2022)
Canine apocrine gland anal sac adenocarcinoma (AGASACA) is an aggressive canine tumor originating from the anal sac glands. Surgical resection, with or without adjuvant chemotherapy, represents the standard of care for this tumor, but the outcome is
Externí odkaz:
https://doaj.org/article/2c22a4ebb1e24b45834909a656d82feb
Autor:
Alexandros Karagiannakos, Maria Adamaki, Antonis Tsintarakis, Borek Vojtesek, Robin Fåhraeus, Vassilis Zoumpourlis, Konstantinos Karakostis
Publikováno v:
Cancers, Vol 14, Iss 3, p 664 (2022)
Cancer is the second leading cause of death globally. One of the main hallmarks in cancer is the functional deregulation of crucial molecular pathways via driver genetic events that lead to abnormal gene expression, giving cells a selective growth ad
Externí odkaz:
https://doaj.org/article/7a553ed90ca74fc88c94bd897f747e29
Autor:
Ceri A Fielding, Michael P Weekes, Luis V Nobre, Eva Ruckova, Gavin S Wilkie, Joao A Paulo, Chiwen Chang, Nicolás M Suárez, James A Davies, Robin Antrobus, Richard J Stanton, Rebecca J Aicheler, Hester Nichols, Borek Vojtesek, John Trowsdale, Andrew J Davison, Steven P Gygi, Peter Tomasec, Paul J Lehner, Gavin W G Wilkinson
Publikováno v:
eLife, Vol 6 (2017)
The human cytomegalovirus (HCMV) US12 family consists of ten sequentially arranged genes (US12-21) with poorly characterized function. We now identify novel natural killer (NK) cell evasion functions for four members: US12, US14, US18 and US20. Using
Externí odkaz:
https://doaj.org/article/0d101cdaf57c4a5ebf6d46b423b8183c
Autor:
Saurabh Jain, Luca Aresu, Stefano Comazzi, Jianguo Shi, Erin Worrall, John Clayton, William Humphries, Sandra Hemmington, Paul Davis, Euan Murray, Asmare A Limeneh, Kathryn Ball, Eva Ruckova, Petr Muller, Borek Vojtesek, Robin Fahraeus, David Argyle, Ted R Hupp
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148366 (2016)
Monoclonal antibodies are leading agents for therapeutic treatment of human diseases, but are limited in use by the paucity of clinically relevant models for validation. Sporadic canine tumours mimic the features of some human equivalents. Developing
Externí odkaz:
https://doaj.org/article/a1216c124e3c4ad38c93dfd866041ade
Autor:
Lisa Scheiblecker, Natalia Marek-Trzonkowska, Marcos Yebenes Mayordomo, Ted R. Hupp, J. Robert O’Neill, Małgorzata Kurkowiak, Bodil Øster, Małgorzata Winniczuk, Ali Al-Saadi, Borek Vojtesek, Giuseppa Grasso, Jakub Faktor
Publikováno v:
RNA Biology. 18:2556-2575
RNA variants that emerge from editing and alternative splicing form important regulatory stages in protein signalling. In this report, we apply an integrated DNA and RNA variant detection workbench to define the range of RNA variants that deviate fro
Autor:
Monikaben Padariya, Mia-Lyn Jooste, Ted Hupp, Robin Fåhraeus, Borek Vojtesek, Fritz Vollrath, Umesh Kalathiya, Konstantinos Karakostis
The p53 tumor suppressor is a transcription factor with roles in cell development, apoptosis, oncogenesis, aging, and homeostasis in response to stresses and infections. p53 is tightly regulated by the MDM2 E3 ubiquitin ligase. The p53–MDM2 pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db0f478154f3475ac9270e943e069b8
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-198296
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-198296
Autor:
Małgorzata, Kurkowiak, Giuseppa, Grasso, Jakub, Faktor, Lisa, Scheiblecker, Małgorzata, Winniczuk, Marcos Yebenes, Mayordomo, J Robert, O'Neill, Bodil, Oster, Borek, Vojtesek, Ali, Al-Saadi, Natalia, Marek-Trzonkowska, Ted R, Hupp
Publikováno v:
RNA Biology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
RNA variants that emerge from editing and alternative splicing form important regulatory stages in protein signalling. In this report, we apply an integrated DNA and RNA variant detection workbench to define the range of RNA variants that deviate fro
Autor:
David J. Clarke, Euan Murray, Jakub Faktor, null AimanMohtar, Borek Vojtesek, C. Logan MacKay, Pat Langridge Smith, Ted R. Hupp
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1870:140806