Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Bore G. Raju"'
1
Investigating the stereochemistry of binding to HIV-1 protease with inhibitors containing isomers of 4-amino-3-hydroxy-5-phenylpentanoic acid
Autor: Milind S. Deshpande, Bore G. Raju
Publikováno v: Biochemical and Biophysical Research Communications. 180:187-190
Summary A series of inhibitors containing all possible isomers of 4-amino-3-hydroxy-5-phenylpentanoic acid was synthesized and tested for inhibition of HIV-1 protease. Incorporation of the (3S,4S) isomer of the t-butyloxycarbonyl protected amino acid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4efced9b3999e4323d97499700c08e3
https://doi.org/10.1016/s0006-291x(05)81274-4
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5
Substrate analog inhibitors of HIV-1 protease containing phenylnorstatine as a transition state element
Autor: Milind S. Deshpande, Bore G. Raju
Publikováno v: Biochemical and biophysical research communications. 180(1)
Summary Substrates of HIV-1 protease are classified into three groups ( A, B and C) based on the amino acid residues present at P1′ and P2′ sites. Replacement of the scissile amide bond by phenylnorstatine in representative substrate analog seque
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d423e2fad5a913f43fa8717a8842077
https://pubmed.ncbi.nlm.nih.gov/1930214
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