Relacorilant plus nab-paclitaxel for the treatment of metastatic pancreatic ductal adenocarcinoma: results from the open-label RELIANT study.

Autor: Borazanci EH; HonorHealth Research Institute, Scottsdale, AZ, United States., Bahary N; Allegheny Health Network Cancer Institute, Pittsburgh, PA, United States., Chung V; City of Hope Comprehensive Cancer Center, Duarte, CA, United States., Huyck TK; Nebraska Cancer Specialists, Omaha, NE, United States., Kio EA; Goshen Center for Cancer Care, Goshen, IN, United States., Chiorean EG; University of Washington, Fred Hutchinson Cancer Center, Seattle, WA, United States., Skeel RT; University of Toledo Medical Center, Toledo, OH, United States., Alese OB; Winship Cancer Institute, Emory University, Atlanta, GA, United States., Cardin DB; Vanderbilt-Ingram Cancer Center, Nashville, TN, United States., Fountzilas C; Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States., Hanna WT; University of Tennessee Graduate School of Medicine, Knoxville, TN, United States., Leal AD; University of Colorado School of Medicine, Aurora, CO, United States., Lee V; Johns Hopkins University School of Medicine, Baltimore, MA, United States., Noonan AM; The Ohio State University, Columbus, OH, United States., Philip PA; Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, United States., Wainberg ZA; University of California School of Medicine, Los Angeles, CA, United States., Pashova H; Corcept Therapeutics Incorporated, Menlo Park, CA, United States., Mann G; Corcept Therapeutics Incorporated, Menlo Park, CA, United States., Oberstein PE; New York University Langone Health, New York, NY, United States.

Publikováno v: The oncologist [Oncologist] 2024 Nov 04; Vol. 29 (11), pp. 957-965.

Malignant ascites in pancreatic cancer: Pathophysiology, diagnosis, molecular characterization, and therapeutic strategies.

Autor: Han MY; Department of Biosciences, Rice University, Houston, TX, United States., Borazanci EH; Department of Oncology, HonorHealth Research Institute, Scottsdale, AZ, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Mar 16; Vol. 13, pp. 1138759. Date of Electronic Publication: 2023 Mar 16 (Print Publication: 2023).

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series.

Autor: Drenner K; Translational Genomic Research Institute (Tgen), Phoenix, AZ 85004, USA., Basu GD; Ashion Analytics, LLC, Phoenix, AZ 85004, USA., Goodman LJ; Ashion Analytics, LLC, Phoenix, AZ 85004, USA., Ozols AA; Ashion Analytics, LLC, Phoenix, AZ 85004, USA., LoBello JR; Ashion Analytics, LLC, Phoenix, AZ 85004, USA., Royce T; Ashion Analytics, LLC, Phoenix, AZ 85004, USA., Gordon MS; HonorHealth Research Institute, Scottsdale, AZ 85258, USA., Borazanci EH; HonorHealth Research Institute, Scottsdale, AZ 85258, USA., Steinbach MA; HonorHealth Research Institute, Scottsdale, AZ 85258, USA., Trent J; Translational Genomic Research Institute (Tgen), Phoenix, AZ 85004, USA., Sharma S; Translational Genomic Research Institute (Tgen), Phoenix, AZ 85004, USA.

Publikováno v: Oncotarget [Oncotarget] 2022 Oct 20; Vol. 13, pp. 1174. Date of Electronic Publication: 2022 Oct 20.

A Phase II, Single-Arm, Open-Label, Bayesian Adaptive Efficacy and Safety Study of PBI-05204 in Patients with Stage IV Metastatic Pancreatic Adenocarcinoma.

Autor: Roth MT; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA., Cardin DB; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA., Borazanci EH; HonorHealth Research Institute, Scottsdale, Arizona, USA., Steinbach M; HonorHealth Research Institute, Scottsdale, Arizona, USA., Picozzi VJ; Virginia Mason Hospital and Medical Center, Seattle, Washington, USA., Rosemury A; AdventHealth Tampa, Tampa, Florida, USA., Wadlow RC; Virginia Cancer Specialists, Fairfax, Virginia, USA., Newman RA; MD Anderson Cancer Center, Houston, Texas, USA., Berlin J; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA.

Publikováno v: The oncologist [Oncologist] 2020 Oct; Vol. 25 (10), pp. e1446-e1450. Date of Electronic Publication: 2020 Jul 02.

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma.

Autor: Bever KM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA.; Co-first authors., Borazanci EH; Virginia Piper Cancer Center at HonorHealth, Scottsdale, AZ, USA.; Molecular Medicine Division, Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.; Co-first authors., Thompson EA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA., Durham JN; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA., Pinero K; Virginia Piper Cancer Center at HonorHealth, Scottsdale, AZ, USA., Jameson GS; Virginia Piper Cancer Center at HonorHealth, Scottsdale, AZ, USA.; Molecular Medicine Division, Translational Genomics Research Institute (TGen), Phoenix, AZ, USA., Vrana A; Virginia Piper Cancer Center at HonorHealth, Scottsdale, AZ, USA., Liu M; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA., Wilt C; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA., Wu AA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA., Fu W; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Wang H; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Yin Y; Department of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai City, China., Leal JP; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Jesus-Acosta A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA., Zheng L; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA., Laheru DA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA., Von Hoff DD; Virginia Piper Cancer Center at HonorHealth, Scottsdale, AZ, USA.; Molecular Medicine Division, Translational Genomics Research Institute (TGen), Phoenix, AZ, USA., Jaffee EM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA., Powell JD; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA., Le DT; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD, USA.; The Skip Viragh Center for Pancreas Cancer at Johns Hopkins, Baltimore, MD, USA.

Publikováno v: Oncotarget [Oncotarget] 2020 May 26; Vol. 11 (21), pp. 1929-1941. Date of Electronic Publication: 2020 May 26 (Print Publication: 2020).