Výsledky vyhledávání - "Borah Spoorenberg"

Akademický článek

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

Autor: Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik JP van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andreasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick CN Rensen

Publikováno v: eLife, Vol 12 (2023)

Analogues of the hepatokine fibroblast growth factor 21 (FGF21) are in clinical development for type 2 diabetes and nonalcoholic steatohepatitis (NASH) treatment. Although their glucose-lowering and insulin-sensitizing effects have been largely unrav

Externí odkaz: https://doaj.org/article/10b3762987d94deeac6dedce6336b7ac

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Author response: FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b99d425453df9a925aa60e01e5fc280
https://doi.org/10.7554/elife.83075.sa2

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FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

Analogues of the hepatokine FGF21 are in clinical development for type 2 diabetes and nonalcoholic steatohepatitis (NASH) treatment. Although their glucose-lowering and insulin-sensitizing effects have been largely unraveled, the mechanisms by which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e6766169da40861a1df700705827a6
https://doi.org/10.1101/2022.09.20.508654

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