Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bor-wen Wu"'
Autor:
Kwang-Yu Chang, Nai-Jung Chiang, Shang-Yin Wu, Chia-Jui Yen, Shang-Hung Chen, Yu-Min Yeh, Chien-Feng Li, Xiaoxing Feng, Katherine Wu, Amanda Johnston, John S. Bomalaski, Bor-Wen Wu, Jianjun Gao, Sumit K. Subudhi, Ahmed O. Kaseb, Jorge M. Blando, Shalini S. Yadav, Peter W. Szlosarek, Li-Tzong Chen
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Background Pegylated arginine deiminase (ADI-PEG 20) is a metabolism-based strategy that depletes arginine, resulting in tumoral stress and cytotoxicity. Preclinically, ADI-PEG 20 modulates T-cell activity and enhances the therapeutic efficacy of pro
Externí odkaz:
https://doaj.org/article/194b984eb9684df9bbd4c8345298b187
Autor:
Peter W. Szlosarek, Piers N. Plowman, Simon Pacey, Michael Sheaff, Ramsay S. Khadeir, Dimitris Paraskevopoulos, Kevin O'Neill, Timothy Crook, John S. Bomalaski, Bor-Wen Wu, Kate Smith, Sarah Jefferies, Tomasz Matys, Raj Jena, Fiona P. Harris, Jim A. Thomson, Amanda Johnston, Xiaoxing Feng, Matthew Williams, Stephen Ellis, Jane Evanson, Richard Shaffer, Nelofer Syed, Rachel Lewis, Peter E. Hall
Effects of ADI-PEG20 on the folate pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2483bde836dfd2025bff2a83268065e1
https://doi.org/10.1158/1078-0432.22474215.v1
https://doi.org/10.1158/1078-0432.22474215.v1
Autor:
Peter W. Szlosarek, Piers N. Plowman, Simon Pacey, Michael Sheaff, Ramsay S. Khadeir, Dimitris Paraskevopoulos, Kevin O'Neill, Timothy Crook, John S. Bomalaski, Bor-Wen Wu, Kate Smith, Sarah Jefferies, Tomasz Matys, Raj Jena, Fiona P. Harris, Jim A. Thomson, Amanda Johnston, Xiaoxing Feng, Matthew Williams, Stephen Ellis, Jane Evanson, Richard Shaffer, Nelofer Syed, Rachel Lewis, Peter E. Hall
Purpose:Patients with recurrent high-grade gliomas (HGG) are usually managed with alkylating chemotherapy ± bevacizumab. However, prognosis remains very poor. Preclinically, we showed that HGGs are a target for arginine depletion with pegargiminase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e3fc5abb0564f3b74b578495cb2833
https://doi.org/10.1158/1078-0432.c.6528723.v1
https://doi.org/10.1158/1078-0432.c.6528723.v1
Autor:
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen
PDF file - 315K, Immunostaining of ASS1, TS, and DHFR in representative urothelial carcinomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58de108aac60a7f2ac818fee63f76d03
https://doi.org/10.1158/0008-5472.22400838.v1
https://doi.org/10.1158/0008-5472.22400838.v1
Autor:
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen
PDF file - 408K, Pyrosequencing data of bladder cancer cell lines and primary bladder cancer samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64184fb943ba4be61d471ac7e3f76496
https://doi.org/10.1158/0008-5472.22400844.v1
https://doi.org/10.1158/0008-5472.22400844.v1
Autor:
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen
PDF file - 177K, Kaplan-Meier plot and log-rank test for disease-specific and metastasis-free survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021474712c23b47d07e7a19ecd0874ed
https://doi.org/10.1158/0008-5472.22400835
https://doi.org/10.1158/0008-5472.22400835
Autor:
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen
PDF file - 65K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fcb4d7055c485382fd9690f4314fa2
https://doi.org/10.1158/0008-5472.22400832
https://doi.org/10.1158/0008-5472.22400832
Autor:
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen
PDF file - 198K, Table S1 Correlation between ASS1 expression and various clinicopathological factors. Table S2 Univariate log-rank analysis for disease-specific survival and metastasis-free survival. Table S3 Correlation between ASS1 IHC and pyroseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492d27ae20aa64d44b55ab7e0e750077
https://doi.org/10.1158/0008-5472.22400829
https://doi.org/10.1158/0008-5472.22400829
Autor:
Peter W. Szlosarek, Chien-Feng Li, Norbert Avril, Jane Sosabowski, Julie Foster, Stephen Mather, Nicholas R. Lemoine, Tim Crook, Yong-Jie Lu, Robert C. Jackson, John S. Bomalaski, Bor-Wen Wu, Claude Chelala, Louise J. Jones, Luis Beltran, Christian Frezza, David Neal, Anne Y. Warren, Hayley C. Whitaker, Rebecca Roylance, Ian Tomlinson, Malgorzata Chmielewska-Kassassir, Laura Lattanzio, Cristiana Lo Nigro, Nelofer Syed, Ming Yuan, Rosalind Cutts, Essam Ghazaly, Barbara Delage, Julius Leyton, Chantelle Hudson, Phuong Luong, Michael D. Allen
PDF file - 802K, Metabolomics of ADI-PEG20 in a corroborative cell line panel (mesothelioma).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e4d879a895f33b98b76e5ee9507bd7
https://doi.org/10.1158/0008-5472.22400841
https://doi.org/10.1158/0008-5472.22400841
Autor:
Chia Jui Yen, Jorge Blando, Ahmed Kaseb, Jianjun Gao, Amanda Johnston, Bor Wen Wu, Kwang Yu Chang, Katherine Wu, John S. Bomalaski, Shang Yin Wu, Shang Hung Chen, Xiaoxing Feng, Shalini S. Yadav, Yu Min Yeh, Peter W. Szlosarek, Chien-Feng Li, Nai Jung Chiang, Li-Tzong Chen, Sumit K. Subudhi
Publikováno v:
Oncoimmunology
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)
article-version (VoR) Version of Record
OncoImmunology, Vol 10, Iss 1 (2021)
Background Pegylated arginine deiminase (ADI-PEG 20) is a metabolism-based strategy that depletes arginine, resulting in tumoral stress and cytotoxicity. Preclinically, ADI-PEG 20 modulates T-cell activity and enhances the therapeutic efficacy of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9022a5ceb11989620c8cf3230d015896
https://doi.org/10.1080/2162402x.2021.1943253
https://doi.org/10.1080/2162402x.2021.1943253