Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Boquan Wu"'
Autor:
Naijin Zhang, Ying Zhang, Yong Chen, Hao Qian, Boquan Wu, Saien Lu, Shilong You, Wancheng Xu, Yuanming Zou, Xinyue Huang, Wenbin Wang, Jingwei Liu, Da Li, Liu Cao, Yingxian Sun
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/7371460d3dba4275bb1ec3a36837470d
Autor:
Shilong You, Jiaqi Xu, Zeyu Yin, Boquan Wu, Pengbo Wang, Mingjun Hao, Cheng Cheng, Mengke Liu, Yuanhui Zhao, Pengyu Jia, Hongkun Jiang, Da Li, Liu Cao, Xingang Zhang, Ying Zhang, Yingxian Sun, Naijin Zhang
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-23 (2023)
Abstract Background Endothelial injury caused by Type 2 diabetes mellitus (T2DM) is considered as a mainstay in the pathophysiology of diabetic vascular complications (DVCs). However, the molecular mechanism of T2DM-induced endothelial injury remains
Externí odkaz:
https://doaj.org/article/e20bf16f9933477887debc2c81095124
Autor:
Zeyu Yin, Shilong You, Shu Zhang, Linlin Zhang, Boquan Wu, Xinyue Huang, Saien Lu, Liu Cao, Ying Zhang, Da Li, Xingang Zhang, Jingwei Liu, Yingxian Sun, Naijin Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115228- (2023)
As a widely used lipid-lowering drug in clinical practice, atorvastatin is widely recognized for its role in protecting vascular endothelium in the cardiovascular system. However, a clear mechanistic understanding of its action is lacking. Here, we f
Externí odkaz:
https://doaj.org/article/44da3cdea1894968ae6e9b0918c6ec3a
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Acute leukemia is a common hematologic tumor with highly genetic heterogeneity, and many factors are involved in the pathogenesis and drug-resistance mechanism. Emerging evidence proves that E3 ubiquitin ligases participate in the acute leukemic sign
Externí odkaz:
https://doaj.org/article/1dcecb525c384ec7bc101010d81cb12e
Autor:
Naijin Zhang, Ying Zhang, Wei Miao, Chuning Shi, Zihan Chen, Boquan Wu, Yuanming Zou, Qiushi Ma, Shilong You, Saien Lu, Xinyue Huang, Jingwei Liu, Jiaqi Xu, Liu Cao, Yingxian Sun
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102238- (2022)
Oxidative stress-associated endothelial damage is the initiation factor of cardiovascular disease, and protein posttranslational modifications play critical roles in this process. Bcl-2-associated athanogene 3 (BAG3) is a molecular chaperone regulato
Externí odkaz:
https://doaj.org/article/cbbb039e0ae140de9747fdcd9e4bc534
Autor:
Naijin Zhang, Ying Zhang, Boquan Wu, Shaojun Wu, Shilong You, Saien Lu, Jingwei Liu, Xinyue Huang, Jiaqi Xu, Liu Cao, Yingxian Sun
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102141- (2021)
Poly(ADP-ribose) polymerase 1 (PARP1) has a major regulatory role in cardiovascular disease. However, inhibiting PARP1 activity does not significantly improve clinical outcomes of cardiovascular disease, which suggests that the regulatory mechanism o
Externí odkaz:
https://doaj.org/article/a1c9e66200eb49a4af50bd127e625217
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Hypertensive nephropathy (HN), mainly caused by chronic hypertension, is one of the major causes of end-stage renal disease. However, the pathogenesis of HN remains unclarified, and there is an urgent need for improved treatments. Gene expression pro
Externí odkaz:
https://doaj.org/article/3cc6527f12d847a3b383cd8340070f7c
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
Oxidative stress-associated endothelial injury is the initial event and major cause of multiple cardiovascular diseases such as atherosclerosis and hypertensive angiopathy. A protein homeostasis imbalance is a critical cause of endothelial injury, an
Externí odkaz:
https://doaj.org/article/f297fe955cf148b29167cab855793394
Autor:
Ying Zhang, Naijin Zhang, Yuanming Zou, Chunyu Song, Kexin Cao, Boquan Wu, Shilong You, Saien Lu, Dong Wang, Jiaqi Xu, Xinyue Huang, Pengyu Zhang, Zihao Fan, Jingwei Liu, Zhongyi Cheng, Zhe Zhang, Chuize Kong, Liu Cao, Yingxian Sun
Publikováno v:
Circulation Research. 132:601-624
Background: Hypertension can lead to podocyte damage and subsequent apoptosis, eventually resulting in glomerulosclerosis. Although alleviating podocyte apoptosis has clinical significance for the treatment of hypertensive nephropathy, an effective t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a64ab184653a2a1f6b4ac05a6e0c136
https://doi.org/10.1161/circresaha.122.321591
https://doi.org/10.1161/circresaha.122.321591
Autor:
Hao Qian, Ying Zhang, Naijin Zhang, Saien Lu, Shaojun Wu, Shilong You, Yingxian Sun, Boquan Wu
Publikováno v:
Journal of Cellular and Molecular Medicine
At present, cardiovascular disease is one of the important factors of human death, and there are many kinds of proteins involved. Sirtuins family proteins are involved in various physiological and pathological activities of the human body. Among them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a04b3e1cbceafb47c959d0ab7916700
https://doi.org/10.1111/jcmm.16618
https://doi.org/10.1111/jcmm.16618