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pro vyhledávání: '"Bootsma A"'
Generative Artificial Intelligence (AI) can be used to automatically generate medical reports based on transcripts of medical consultations. The aim is to reduce the administrative burden that healthcare professionals face. The accuracy of the genera
Externí odkaz:
http://arxiv.org/abs/2311.13273
In the first part of this paper, we review old and new results about the influence of host population heterogeneity on (various characteristics of) epidemic outbreaks. In the second part we highlight a modelling issue that so far has received little
Externí odkaz:
http://arxiv.org/abs/2308.06593
Autor:
Hamza Bakhtiar, Marina N. Sharifi, Kyle T. Helzer, Yue Shi, Matthew L. Bootsma, Tianfu A. Shang, Matthew R. Chrostek, Tracy J. Berg, S. Carson Callahan, Viridiana Carreno, Grace C. Blitzer, Malinda T. West, Ruth M. O’Regan, Kari B. Wisinski, Martin Sjöström, Shuang G. Zhao
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract In preclinical studies, p53 loss of function impacts chemotherapy response, but this has not been consistently validated clinically. We trained a TP53-loss phenocopy gene expression signature from pan-cancer clinical samples in the TCGA. In
Externí odkaz:
https://doaj.org/article/b735ca97c9414b91b5344298927abc08
The aim of this short note is twofold. We formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key feature is that
Externí odkaz:
http://arxiv.org/abs/2307.16749
Autor:
Amber P. van der Zalm, Mark P. G. Dings, Paul Manoukian, Hannah Boersma, Reimer Janssen, Peter Bailey, Jan Koster, Danny Zwijnenburg, Richard Volckmann, Sanne Bootsma, Cynthia Waasdorp, Monique van Mourik, Dionne Blangé, Tom van den Ende, César I. Oyarce, Sarah Derks, Aafke Creemers, Eva A. Ebbing, Gerrit K. Hooijer, Sybren L. Meijer, Mark I. van Berge Henegouwen, Jan Paul Medema, Hanneke W. M. van Laarhoven, Maarten F. Bijlsma
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Despite the advent of neoadjuvant chemoradiotherapy (CRT), overall survival rates of esophageal adenocarcinoma (EAC) remain low. A readily induced mesenchymal transition of EAC cells contributes to resistance to CRT. Methods In th
Externí odkaz:
https://doaj.org/article/d7fc9df802d34addb7ab614129c458e9
Autor:
Loes Oomen, Charlotte M. H. H. T. Bootsma-Robroeks, Antonia H. M. Bouts, Mar Carbonell Pradas, Romy Gander, Katrin Kienzl-Wagner, Paul König, Pedro Lopez Pereira, Olivier Dunand, Sara M. F. S. Mosca, Michal Pac, Ludmila Podracka, Agnieszka A. Prytula, Maria Sangermano, Renata Vitkevic, Jakub Zieg, Loes F. M. van der Zanden, Wout F. J. Feitz, Liesbeth L. de Wall
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundPediatric kidney transplantations are rarely performed, and there is limited knowledge about the diversity in current clinical practices across Europe. This study aims to explore the utility of clinical snapshot studies in identifying these
Externí odkaz:
https://doaj.org/article/5446d87be2d04f74a3041f048e52986b
Autor:
Dajia Liu, Amber P. van der Zalm, Jan Koster, Sanne Bootsma, Cesar Oyarce, Hanneke W.M. van Laarhoven, Maarten F. Bijlsma
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107315- (2024)
Epithelial-mesenchymal transition (EMT) has been identified as a driver of therapy resistance, particularly in esophageal adenocarcinoma (EAC), where transforming growth factor beta (TGF-β) can induce this process. Inhibitors of TGF-β may counterac
Externí odkaz:
https://doaj.org/article/693617776d904183909d7cef03180eb3
Autor:
Dajia Liu, Lihui Guo, Cynthia Waasdorp, Sybren L. Meijer, Sanne Bootsma, Cesar Oyarce, Maarten F. Bijlsma, Hanneke W.M. van Laarhoven
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117261- (2024)
Background: Long-term anti-angiogenesis leads to pruned vasculature, densely deposited extracellular matrix (ECM), and consequently reduced chemotherapy delivery in esophagogastric cancer (EGC). To address this issue, we evaluated the efficacy of add
Externí odkaz:
https://doaj.org/article/4443b6f6d2ae4872bc3299247fbd9f68
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
In the manual ball-and-beam task, participants have to control a ball that is rolling continuously on a long and hand-held beam. Since the task can be performed individually, in a solo action setting, as well as collaboratively, in a (dyadic) joint a
Externí odkaz:
https://doaj.org/article/82be478f6466416c80bb28d35ae7b081
Autor:
Suzanne Arends, Silvia C Liefers, Frans G M Kroese, Arjan Vissink, Hendrika Bootsma, Bert van der Vegt, Alja J Stel, Fred K L Spijkervet, Gwenny M Verstappen, Wineke Armbrust, Geertje Elizabeth Legger, Uzma Nakshbandi, Martha S van Ginkel, Lisette de Wolff
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Objectives The aim of this study was to assess the histopathological features of the parotid glands in patients with paediatric-onset Sjögren’s disease (pedSjD) in comparison to patients with adult-onset Sjögren’s disease (adSjD).Methods This s
Externí odkaz:
https://doaj.org/article/9dca821a3c7546239770a9d6e33b9d96