Zobrazeno 1 - 10
of 426
pro vyhledávání: '"Boon-Huat Bay"'
Autor:
Madhulika Tripathi, Karine Gauthier, Reddemma Sandireddy, Jin Zhou, Priyanka Guptta, Suganya Sakthivel, Wei Wen Teo, Yadanar Than Naing, Kabilesh Arul, Keziah Tikno, Sung-Hee Park, Yajun Wu, Lijin Wang, Boon-Huat Bay, Lei Sun, Vincent Giguere, Pierce K.H. Chow, Sujoy Ghosh, Donald P. McDonnell, Paul M. Yen, Brijesh K. Singh
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101997- (2024)
Objective: Currently, little is known about the mechanism(s) regulating global and specific protein translation during metabolic dysfunction-associated steatohepatitis (MASH; previously known as non-alcoholic steatohepatitis, NASH). Methods: Unbiased
Externí odkaz:
https://doaj.org/article/17f87e3dbde54cfa8579d8857c0fe2d1
Autor:
Pei-Jou Chua, Suet-Hui Ow, Cheng-Teng Ng, Wan-Hong Huang, Jie-Ting Low, Puay Hoon Tan, Michael W.Y. Chan, Boon-Huat Bay
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Peroxiredoxin 3 (PRDX3), a mitochondrial hydrogen peroxide scavenger, is known to be upregulated during tumorigenesis and cancer progression. In this study, we provide evidence for the first time that PRDX3 could regulate cellular signaling
Externí odkaz:
https://doaj.org/article/c78a2197f5da41e3bc43c7787aa988cd
Autor:
Sangam Rajak, Sherwin Xie, Archana Tewari, Sana Raza, Yajun Wu, Boon-Huat Bay, Paul M. Yen, Rohit A. Sinha
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101286- (2021)
Objective: Crinophagy is a secretory granule-specific autophagic process that regulates hormone content and secretion in endocrine cells. However, despite being one of the earliest described autophagic processes, its mechanism of action and regulatio
Externí odkaz:
https://doaj.org/article/9d5b34b8cf7b486dbe260df9e11bf0cd
Autor:
Winifred W. Yau, Kiraely Adam Wong, Jin Zhou, Nivetha Kanakaram Thimmukonda, Yajun Wu, Boon-Huat Bay, Brijesh Kumar Singh, Paul Michael Yen
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102434- (2021)
Summary: Autophagy plays an important role in lipid breakdown, mitochondrial turnover, and mitochondrial function during brown adipose tissue (BAT) activation by thyroid hormone, but its role in BAT during adaptive thermogenesis remains controversial
Externí odkaz:
https://doaj.org/article/28ac87c58a7c403097bab2ff00935f85
Autor:
Hariharan Ezhilarasu, Dinesh Vishalli, S. Thameem Dheen, Boon-Huat Bay, Dinesh Kumar Srinivasan
Publikováno v:
Nanomaterials, Vol 10, Iss 6, p 1234 (2020)
Diabetes mellitus (DM) is a common endocrine disease characterized by a state of hyperglycemia (higher level of glucose in the blood than usual). DM and its complications can lead to diabetic foot ulcer (DFU). DFU is associated with impaired wound he
Externí odkaz:
https://doaj.org/article/96f915742db34a12ab94fae40f750d72
Autor:
Chinnasamy Gandhimathi, Ying Jie Quek, Hariharan Ezhilarasu, Seeram Ramakrishna, Boon-Huat Bay, Dinesh Kumar Srinivasan
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5135 (2019)
Multifunctional nanofibrous scaffolds for effective bone tissue engineering (BTE) application must incorporate factors to promote neovascularization and tissue regeneration. In this study, silica-coated gold nanoparticles Au(SiO2) were tested for the
Externí odkaz:
https://doaj.org/article/faa33de07c2b4078b878b9a95ff79946
Publikováno v:
The Scientific World Journal, Vol 8, Pp 270-274 (2008)
Heat shock proteins (HSPs) are evolutionarily conserved molecules and play important roles in fundamental cellular processes. They serve as molecular chaperones and hence provide a protective function in ensuring cell survival and repair of cellular
Externí odkaz:
https://doaj.org/article/cbd3c863a83d44189d41b1332c8e49f5
Autor:
Jin Zhou, Benjamin Livingston Farah, Rohit Anthony Sinha, Yajun Wu, Brijesh Kumar Singh, Boon-Huat Bay, Chung S Yang, Paul Michael Yen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87161 (2014)
Epigallocatechin gallate (EGCG) is a major polyphenol in green tea that has been shown to have anti-inflammatory, anti-cancer, anti-steatotic effects on the liver. Autophagy also mediates similar effects; however, it is not currently known whether EG
Externí odkaz:
https://doaj.org/article/2f171db8aac94feba866b24eb5e08ac2
Autor:
Benjamin L Farah, Rohit A Sinha, Yajun Wu, Brijesh K Singh, Jin Zhou, Boon-Huat Bay, Paul M Yen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98155 (2014)
Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function. However, cu
Externí odkaz:
https://doaj.org/article/bc3c012a92f1433ab6ac6332fd7c90f4
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e50964 (2013)
Vascular endothelial growth factor (VEGF) is an angiogenic mitogen involved in promoting tumor angiogenesis inside the body. VEGF is a key protein required for progression of tumor from benign to malignant phenotype. In this study, we investigated th
Externí odkaz:
https://doaj.org/article/416f8744d0fd4579b76f38ea40b729e6