Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Boon Seng Wong"'
Autor:
Davynn Gim Hoon Tan, Belinda Melody Bernadette Boo, Cheyenne Shuen Chong, Megan Michelle Ling-Li Tan, Boon-Seng Wong
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionDementia is a neurodegenerative condition characterized by cognitive decline and increased functional dependency. With most persons living with dementia (PLWDs) residing at home, home-based interventions provide a convenient and individua
Externí odkaz:
https://doaj.org/article/ec4f9a2bf0df4b3485a8ea3b36615eb7
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 260-265 (2014)
The diabetic drug rosiglitazone was reported to improve glucose tolerance in insulin-resistant ApoE3 but not ApoE4 knock-in mice. We therefore examined whether apolipoprotein E (ApoE) has genotype-specific effects on liver insulin function. At 12 wee
Externí odkaz:
https://doaj.org/article/23a5b566d65e46ab89f51cc70eb0ceb0
Autor:
Boon-Seng Wong, Minhua Luo, Man-Sun Sy, Jing Shi, Lili Cai, Chaoyang Li, Zhenxing Gao, Xiaoping Dong
Publikováno v:
Biochemical and Biophysical Research Communications. 509:570-576
The conversion of the normal prion protein (PrP) into a scrapie prion (PrPSc) is incompletely understood. Theoretically, the smallest PrP aggregate is a dimer. Human PrP contains two cysteines at positions 179 (C179) and 214 (C214) enabling disulfide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b5752c34e8b2b360c1e9cd19e90eb3
https://doi.org/10.1016/j.bbrc.2018.12.113
https://doi.org/10.1016/j.bbrc.2018.12.113
Autor:
Deborah Amanda Goh, Yanhong Dong, Wah Yean Lee, Way Inn Koay, Stephen Ziyang Tay, Danny Soon, Christopher Chen, Claire Frances Brittain, Stephen Loucian Lowe, Boon-Seng Wong
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96874 (2014)
BACKGROUND: Diabetes is reported to be linked to poorer cognitive function. The purpose of this study is to examine (a) clinical correlation between cognitive function and the biochemical perturbations in T2DM, and (b) the impact of statin treatment
Externí odkaz:
https://doaj.org/article/d93f933e6c7c44479a9192acde6b9a24
Autor:
Hoon Tan, Davynn Gim, Boo, Belinda Melody Bernadette, Cheyenne Shuen Chong, Ling-Li Tan, Megan Michelle, Boon-Seng Wong
Publikováno v:
Frontiers in Aging Neuroscience; 8/11/2022, Vol. 14, p1-23, 23p
Autor:
Saima Hilal, Narayanaswamy Venketasubramanian, Yanan Zhu, M. Kamran Ikram, Mitchell K.P. Lai, Boon Seng Wong, Yuek Ling Chai, Christopher Chen
Publikováno v:
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 7, 41-47. Elsevier
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Introduction Neuroinflammation and cerebrovascular disease (CeVD) have been implicated in cognitive impairment and Alzheimer's disease (AD). The present study aimed to examine serum inflammatory markers in preclinical stages of dementia and in AD, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11927c3721d6b8c6a942237c4d805236
https://doi.org/10.1016/j.dadm.2017.01.001
https://doi.org/10.1016/j.dadm.2017.01.001
Autor:
Bernard Poon-Lap Chan, Hock Luen Teoh, Esther Wan Yee Shuang, Jing Xu, Yanhong Dong, Christopher Chen, Boon Seng Wong, Ma Serrie P. Suministrado, Narayanaswamy Venketasubramanian, Raymond C.S. Seet, Vivek Sharma
Publikováno v:
Journal of Neuroimaging. 27:326-332
BACKGROUND Poststroke vascular cognitive impairment is highly prevalent with significant functional consequences. However, reliable biomarkers for early prediction of cognitive decline after acute ischemic stroke (AIS) are not well established. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecfebaa8069ce4bac5afc7a131e104af
https://doi.org/10.1111/jon.12395
https://doi.org/10.1111/jon.12395
Publikováno v:
Neuromolecular medicine. 20(1)
Apolipoprotein E4 (ApoE4) is the strongest genetic risk factor for sporadic Alzheimer's disease (AD), where inheritance of this isoform predisposes development of AD in a gene dose-dependent manner. Although the mode of action of ApoE4 on AD onset an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf10316e4883cb4f5a212773ae1a08a9
https://pubmed.ncbi.nlm.nih.gov/29450841
https://pubmed.ncbi.nlm.nih.gov/29450841
Publikováno v:
Food Funct.. 5:2043-2051
It is unclear how the nutritional supplement chicken extract (CE) enhances cognition. Human apolipoprotein E (ApoE) can regulate cognition and this isoform-dependent effect is associated with the N-methyl-d-aspartate receptor (NMDAR). To understand i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d42a43e753cb6c90bb2d0b9e820b95
https://doi.org/10.1039/c4fo00428k
https://doi.org/10.1039/c4fo00428k