Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Bonsu, Ku"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The N-end rule pathway is a proteolytic system involving the destabilization of N-terminal amino acids, known as N-degrons, which are recognized by N-recognins. Dysregulation of the N-end rule pathway results in the accumulation of undesired
Externí odkaz:
https://doaj.org/article/4800e1d332b54425963b351ee3b2552f
Autor:
Jong Il Ahn, Liang Zhang, Harsha Ravishankar, Lixin Fan, Klara Kirsch, Yan Zeng, Lingjun Meng, Jung-Eun Park, Hye-Yeoung Yun, Rodolfo Ghirlando, Buyong Ma, David Ball, Bonsu Ku, Ruth Nussinov, Jeremy D. Schmit, William F. Heinz, Seung Jun Kim, Tatiana Karpova, Yun-Xing Wang, Kyung S. Lee
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/4954415703224bd39f8ad4b7d54ac61c
Autor:
Jong Il Ahn, Liang Zhang, Harsha Ravishankar, Lixin Fan, Klara Kirsch, Yan Zeng, Lingjun Meng, Jung-Eun Park, Hye-Yeoung Yun, Rodolfo Ghirlando, Buyong Ma, David Ball, Bonsu Ku, Ruth Nussinov, Jeremy D. Schmit, William F. Heinz, Seung Jun Kim, Tatiana Karpova, Yun-Xing Wang, Kyung S. Lee
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Abstract Proper organization of intracellular assemblies is fundamental for efficient promotion of biochemical processes and optimal assembly functionality. Although advances in imaging technologies have shed light on how the centrosome is organized,
Externí odkaz:
https://doaj.org/article/06aa6e8547484fe7b186bef73965f8dc
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-12 (2023)
Abstract Influenza virus is one of the most challenging viruses threating human health. Since infection with influenza virus triggers inflammatory responses and induces cell death, the molecular and cellular mechanisms by which the virus-infected cel
Externí odkaz:
https://doaj.org/article/a1a7730378854f7589fc327f92a4a331
Autor:
Vijay Gupta, Afif Ben-Mahmoud, Bonsu Ku, Dinesh Velayutham, Zainab Jan, Abdi Yousef Aden, Ahmad Kubbar, Fouad Alshaban, Lawrence W. Stanton, Puthen Veettil Jithesh, Lawrence C. Layman, Hyung-Goo Kim
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
This study investigated the genetic underpinnings of autism spectrum disorder (ASD) in a Middle Eastern cohort in Qatar using exome sequencing. The study identified six candidate autism genes in independent simplex families, including both four known
Externí odkaz:
https://doaj.org/article/c16ac00a1bcd4c16a7757d6b44f8f09c
Autor:
Dahwan Lim, So-Hui Choe, Sein Jin, Seulgi Lee, Younjin Kim, Ho-Chul Shin, Joon Sig Choi, Doo-Byoung Oh, Seung Jun Kim, Jinho Seo, Bonsu Ku
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002156 (2023)
Bak is a critical executor of apoptosis belonging to the Bcl-2 protein family. Bak contains a hydrophobic groove where the BH3 domain of proapoptotic Bcl-2 family members can be accommodated, which initiates its activation. Once activated, Bak underg
Externí odkaz:
https://doaj.org/article/18ba468a3078463da093e2f3ce29b09f
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
O-GlcNAc modification of proteins often has crosstalk with protein phosphorylation. These posttranslational modifications are highly dynamic events that modulate a wide range of cellular processes. Owing to the physiological and pathological signific
Externí odkaz:
https://doaj.org/article/e1100c5a02624fc1acaa9cbaa8096183
Autor:
Bonsu Ku
Publikováno v:
Current Protein & Peptide Science. 24:296-306
Abstract: Anti-apoptotic and anti-autophagic Bcl-2 homologues commonly contain a hydrophobic groove in which the BH3 domain is accommodated. The BH3 domain is usually considered a feature of Bcl-2 family members; however, it has also been found in va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df9e613a17e9fe4dac4db076f2fbf947
https://doi.org/10.2174/1389203724666230314164040
https://doi.org/10.2174/1389203724666230314164040
Publikováno v:
BIODESIGN. 10:69-72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663c5540dc737c8b0b0b42f328fcaefa
https://doi.org/10.34184/kssb.2022.10.4.69
https://doi.org/10.34184/kssb.2022.10.4.69
Autor:
Dahwan Lim, Sein Jin, Ho-Chul Shin, Wantae Kim, Joon Sig Choi, Doo-Byoung Oh, Seung Jun Kim, Jinho Seo, Bonsu Ku
Publikováno v:
Biochemical and Biophysical Research Communications. 625:174-180
Antiapoptotic B-cell lymphoma-2 (Bcl-2) proteins suppress apoptosis by interacting with proapoptotic regulators. They commonly contain a hydrophobic groove where the Bcl-2 homology 3 (BH3) domain of Bcl-2 family members or BH3 domain-containing non-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af6c7f0dc88ba4c4b4d4523771ed4e9
https://doi.org/10.1016/j.bbrc.2022.08.009
https://doi.org/10.1016/j.bbrc.2022.08.009