Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Bonnie R Fletcher"'
Autor:
James F Castellano, Bonnie R Fletcher, Bennett Kelley-Bell, David H Kim, Michela Gallagher, Peter R Rapp
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33249 (2012)
Mounting evidence linking epigenetic regulation to memory-related synaptic plasticity raises the possibility that altered chromatin modification dynamics might contribute to age-dependent cognitive decline. Here we show that the coordinated orchestra
Externí odkaz:
https://doaj.org/article/4ae4cec1897b47c4879a82a03136262f
Autor:
Supriyo De, James F. Castellano, Gautam Kundu, Peter R. Rapp, Joshua Kittleson, Kevin G. Becker, Bonnie R. Fletcher, Craig Myrum
Publikováno v:
Mol Neurobiol
Aging is accompanied by aberrant gene expression that ultimately affects brain plasticity and the capacity to form long-term memories. Immediate-early genes (IEGs) play an active role in these processes. Using a rat model of normal cognitive aging, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa2e13edfd4247a3e146ef7810234a2
https://doi.org/10.1007/s12035-020-01915-4
https://doi.org/10.1007/s12035-020-01915-4
Autor:
Gordon S. Hill, Bonnie R. Fletcher, Michela Gallagher, Jeffrey M. Long, Peter R. Rapp, Matthew L. Shapiro
Publikováno v:
Neurobiology of Learning and Memory. 115:58-67
Memory decline is a common feature of aging. Expression of the immediate-early gene Arc is necessary for normal long-term memory, and although experience dependent Arc transcription is reportedly reduced in the aged rat hippocampus, it has not been c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7671f7414d647ba162dbcc9e4000c6db
https://doi.org/10.1016/j.nlm.2014.08.007
https://doi.org/10.1016/j.nlm.2014.08.007
Autor:
Bonnie R. Fletcher, James F. Castellano, Bennett Kelley-Bell, Angila S. Sewal, Peter R. Rapp, Jeffrey M. Long, Holger Patzke, David H. Kim
Publikováno v:
Hippocampus. 24:1006-1016
Converging results link histone acetylation dynamics to hippocampus-dependent memory, including evidence that histone deacetylase inhibitor (HDACi) administration enhances long-term memory. Previously, we demonstrated that aging disrupts the coordina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c2879df53d7e667c8e9308e1bde7e23
https://doi.org/10.1002/hipo.22286
https://doi.org/10.1002/hipo.22286
Autor:
Peter R. Rapp, Michael E. Calhoun, Michela Gallagher, Diana C. Zentko, Bonnie R. Fletcher, Stella S. Yi
Publikováno v:
Neurobiology of Aging. 29:1256-1264
Age-related impairments in hippocampus-dependent learning and memory tasks are not associated with a loss of hippocampal neurons, but may be related to alterations in synaptic integrity. Here we used stereological techniques to estimate spine number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb618e36cc670cde8acce74ef436f64
https://doi.org/10.1016/j.neurobiolaging.2007.02.013
https://doi.org/10.1016/j.neurobiolaging.2007.02.013
Autor:
Kevin G. Becker, Bonnie R. Fletcher, Peter R. Rapp, Yongqing Zhang, Elin Lehrmann, Angila S. Sewal, Pul Park, Jeffrey M. Long, Evelyn Perez, Holger Patzke
The therapeutic potential of histone deacetylase inhibitor (HDACi) treatment has attracted considerable attention in the emerging area of cognitive neuroepigenetics. The possibility that ongoing cognitive experience importantly regulates the cell bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bf0947264c5001a4e8319e4d2723ae
https://europepmc.org/articles/PMC4540806/
https://europepmc.org/articles/PMC4540806/
Autor:
Peter R. Rapp, Bonnie R. Fletcher
Publikováno v:
Handbook of Psychology, Second Edition
Aging in the absence of neurodegenerative disease is frequently accompanied by deficits in memory and other cognitive capacities. Although relatively modest in severity, these changes diminish the quality of life and pose a significant challenge to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78fabd17c2bc6afa8644429f85fc8288
https://doi.org/10.1002/9781118133880.hop203024
https://doi.org/10.1002/9781118133880.hop203024
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(5)
The immediate-early gene (IEG) Arc is transcribed after behavioral and physiological treatments that induce synaptic plasticity and is implicated in memory consolidation. The relative contributions of neuronal activity and learning-related plasticity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f8c6cc1e984a46e781341ba5bcbc9d
https://pubmed.ncbi.nlm.nih.gov/16452674
https://pubmed.ncbi.nlm.nih.gov/16452674
Autor:
Michael F. Romero, Christopher M. Sciortino, Bonnie R. Fletcher, Peter J. Harte, Lamara D. Shrode
Publikováno v:
American journal of physiology. Cell physiology. 281(2)
Na+-dependent Cl−/HCO[Formula: see text]exchange activity helps maintain intracellular pH (pHi) homeostasis in many invertebrate and vertebrate cell types. Our laboratory cloned and characterized a Na+-dependent Cl−/HCO[Formula: see text] exchang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0abff955a80ec9169748f8c6d9cd27
https://pubmed.ncbi.nlm.nih.gov/11443044
https://pubmed.ncbi.nlm.nih.gov/11443044