Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bonnie Patchen"'
Autor:
Tiago Koppe, Bonnie Patchen, Aaron Cheng, Manoj Bhasin, Chris Vulpe, Robert E. Schwartz, Jose Maria Moreno‐Navarrete, Jose Manuel Fernandez‐Real, Pavlos Pissios, Paula G. Fraenkel
Publikováno v:
Hepatology Communications, Vol 1, Iss 8, Pp 803-815 (2017)
Iron overload causes the generation of reactive oxygen species that can lead to lasting damage to the liver and other organs. The goal of this study was to identify genes that modify the toxicity of iron overload. We studied the effect of iron overlo
Externí odkaz:
https://doaj.org/article/1984d87b3c284ddf9d44de9cc56f0ec5
Autor:
Alexander Vonderschmidt, Kathryn Bass, Bonnie Patchen, Kathryn Arnold, Eric Shiroma, Eleanor Simonsick, Dana Handock, Patricia Cassano
Publikováno v:
Current Developments in Nutrition. 6:955
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bca8f0261a9194daa894d844ac83208
https://doi.org/10.1093/cdn/nzac067.075
https://doi.org/10.1093/cdn/nzac067.075
Autor:
Manoj Bhasin, Robert E. Schwartz, Chris D. Vulpe, José María Moreno-Navarrete, José Manuel Fernández-Real, Paula G. Fraenkel, Aaron Cheng, Bonnie Patchen, Tiago Koppe, Pavlos Pissios
Publikováno v:
Hepatology Communications
Iron overload causes the generation of reactive oxygen species that can lead to lasting damage to the liver and other organs. The goal of this study was to identify genes that modify the toxicity of iron overload. We studied the effect of iron overlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74fa5428086f8555d2494f20110d7a3
https://pubmed.ncbi.nlm.nih.gov/29404495
https://pubmed.ncbi.nlm.nih.gov/29404495
Autor:
Young Ah Seo, Paula G. Fraenkel, Bonnie Patchen, Aaron Cheng, Marianne Wessling-Resnick, Tiago Koppe
Hepcidin, a peptide produced in the liver, decreases intestinal iron absorption and macrophage iron release by causing degradation of the iron exporter, ferroportin. Because its levels are inappropriately low in patients with iron overload syndromes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a800ae57cbc0a39e6a70c8dce3d66f30
https://europepmc.org/articles/PMC5094460/
https://europepmc.org/articles/PMC5094460/
Autor:
Aileen W. Zhen, Bonnie Patchen, Vera Gaun, Michael P. Pollastri, Paula G. Fraenkel, Aleksandr Andreev, Josephine Volovetz
Publikováno v:
Blood cells, moleculesdiseases. 53(4)
Hepcidin, a peptide hormone produced in the liver, decreases intestinal iron absorption and macrophage iron release via effects on ferroportin. Bone morphogenic protein and Stat3 signaling regulate Hepcidin's transcription. Hepcidin is a potential dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0148cb07c7052617cedd413c15c97b
https://pubmed.ncbi.nlm.nih.gov/24998898
https://pubmed.ncbi.nlm.nih.gov/24998898
Autor:
Pavlos Pissios, Bonnie Patchen, Aaron Cheng, Chris D. Vulpe, Manoj Bhasin, Paula G. Fraenkel, Robert K. Schwartz, José Manuel Fernández-Real, Tiago Koppe
Publikováno v:
Blood. 128:204-204
Iron overload causes the generation of reactive oxygen species, which can lead to liver failure, particularly when it occurs in conjunction with nonalcoholic fatty liver disease (NAFLD) or viral hepatitis. Previously, we studied the effects of iron d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26fa3d5d01716e4445b3f89bba65a31f
https://doi.org/10.1182/blood.v128.22.204.204
https://doi.org/10.1182/blood.v128.22.204.204
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a3bfbb8b5dd538ae86af632c38b53e
https://doi.org/10.1096/fasebj.27.1_supplement.634.17
https://doi.org/10.1096/fasebj.27.1_supplement.634.17
Autor:
Steven J. Swoap, Bonnie Patchen
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b088ac32e9f5336fee430121c9c7a2fb
https://doi.org/10.1096/fasebj.26.1_supplement.1086.24
https://doi.org/10.1096/fasebj.26.1_supplement.1086.24
Publikováno v:
Blood. 124:4025-4025
Hepcidin, a peptide hormone produced in the liver, decreases intestinal iron absorption and macrophage iron release by causing internalization and degradation of the iron exporter ferroportin. Because its levels are inappropriately low in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55037f5ee3fe76066ba49f3a3099b172
https://doi.org/10.1182/blood.v124.21.4025.4025
https://doi.org/10.1182/blood.v124.21.4025.4025
Publikováno v:
Blood. 120:611-611
Abstract 611 Hepcidin, a peptide hormone produced in the liver, decreases intestinal iron absorption and macrophage iron release via effects on ferroportin. Hepcidin is a potential drug target for patients with iron overload syndromes because its lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3e93cfd883ca1c4550f15cdb214e659
https://doi.org/10.1182/blood.v120.21.611.611
https://doi.org/10.1182/blood.v120.21.611.611