Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Bonnie N. Dittel"'
Autor:
Yuanhua Cai, Jocelyn A. Schroeder, Weiqing Jing, Cody Gurski, Calvin B. Williams, Shaoyuan Wang, Bonnie N. Dittel, Qizhen Shi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system with no cure yet. Here, we report genetic engineering of hematopoietic stem cells (HSCs) to express myelin oligodendrocyte glycoprotein (MOG), specific
Externí odkaz:
https://doaj.org/article/ec6a2fddd5f34326a50e945eeb517ef7
Autor:
Savannah D. Neu, Bonnie N. Dittel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory B cell or “Breg” is a broad term that represents the anti-inflammatory activity of B cells, but does not describe their individual phenotypes, specific mechanisms of regulation or relevant disease contexts. Thus, given the variety of B
Externí odkaz:
https://doaj.org/article/5df9ec53512b4e208ce60891b213290c
Autor:
Avijit Ray, Mohamed I. Khalil, Kirthi L. Pulakanti, Robert T. Burns, Cody J. Gurski, Sreemanti Basu, Demin Wang, Sridhar Rao, Bonnie N. Dittel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
B cells produce antibodies to mediate various immune functions, but are also reported to negatively regulate immune responses. Here, the authors show that a subset of mature B cells expressing low levels of IgD, present in both mice and human, may pu
Externí odkaz:
https://doaj.org/article/a6be2f1b8c89426188dea0ff476a0e02
Autor:
Cody J. Gurski, Bonnie N. Dittel
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8246 (2022)
Macrophages are present in every tissue in the body and play essential roles in homeostasis and host defense against microorganisms. Some tissue macrophages derive from the yolk sac/fetal liver that populate tissues for life. Other tissue macrophages
Externí odkaz:
https://doaj.org/article/f0e05ce30aae4af7954d35044c928471
Autor:
Anna Strzepa, Cody J. Gurski, Landon J. Dittel, Marian Szczepanik, Kirkwood A. Pritchard, Bonnie N. Dittel
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
BackgroundAllergic contact dermatitis (ACD) is a common skin disorder affecting an estimated 15-20% of the general population. The mouse model of ACD is contact hypersensitivity (CHS), which consists of two phases: induction and elicitation. Although
Externí odkaz:
https://doaj.org/article/2bda9755192344759c8cc63b78bb4c21
Autor:
Alicia López, Noelia Aparicio, M. Ruth Pazos, M. Teresa Grande, M. Asunción Barreda-Manso, Irene Benito-Cuesta, Carmen Vázquez, Mario Amores, Gonzalo Ruiz-Pérez, Elena García-García, Margaret Beatka, Rosa M. Tolón, Bonnie N. Dittel, Cecilia J. Hillard, Julián Romero
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background Because of their low levels of expression and the inadequacy of current research tools, CB2 cannabinoid receptors (CB2R) have been difficult to study, particularly in the brain. This receptor is especially relevant in the context
Externí odkaz:
https://doaj.org/article/1c0c192ba5124243a8c6c06f7122bce8
Autor:
Savannah D. Neu, Anna Strzepa, Dustin Martin, Mary G. Sorci-Thomas, Kirkwood A. Pritchard, Bonnie N. Dittel
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1338 (2021)
Plaque psoriasis is a common inflammatory condition of the skin characterized by red, flaking lesions. Current therapies for plaque psoriasis target many facets of the autoimmune response, but there is an incomplete understanding of how oxidative dam
Externí odkaz:
https://doaj.org/article/e4ad21f2ec274fa2892478038a02549a
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
In recent years the innate immune system has been shown to be crucial for the pathogenesis of postoperative pain. The mediators released by innate immune cells drive the sensitization of sensory neurons following injury by directly acting on peripher
Externí odkaz:
https://doaj.org/article/241f318e46684bb1b01986e51c078ad6
Autor:
Nichole M. Miller, Leah P. Shriver, Vijaya L. Bodiga, Avijit Ray, Sreemanti Basu, Rajiv Ahuja, Arundhati Jana, Kalipada Pahan, Bonnie N. Dittel
Publikováno v:
ASN Neuro, Vol 5 (2013)
MS (multiple sclerosis) is the most prevalent autoimmune disease of the CNS (central nervous system) historically characterized as an inflammatory and demyelinating disease. More recently, extensive neuronal pathology has lead to its classification a
Externí odkaz:
https://doaj.org/article/958cf89618d0460ead83830f4ea5992b
Publikováno v:
ImmunoHorizons. 6(7)
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory autoimmune disease of the CNS that resembles multiple sclerosis and provides a useful animal model for the evaluation of mechanisms of action for potential immunomodulatory therapies.