Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bonnie L. Phillips"'
Autor:
Joshua A. Eudailey, Maria L. Dennis, Morgan E. Parker, Bonnie L. Phillips, Tori N. Huffman, Camden P. Bay, Michael G. Hudgens, Roger W. Wiseman, Justin J. Pollara, Genevieve G. Fouda, Guido Ferrari, David J. Pickup, Pamela A. Kozlowski, Koen K. A. Van Rompay, Kristina De Paris, Sallie R. Permar
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Mother-to-child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) contributes to an estimated 150,000 new infections annually. Maternal vaccination has proven safe and effective at mitigating the impact of other neonatal pat
Externí odkaz:
https://doaj.org/article/24cdc256f1384177999d95017eb64e03
Autor:
Bonnie L Phillips, Uma S Gautam, Allison N Bucsan, Taylor W Foreman, Nadia A Golden, Tianhua Niu, Deepak Kaushal, Smriti Mehra
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0180413 (2017)
CD4+ T-cell mediated Th1 immune responses are critical for immunity to TB. The immunomodulatory protein, lymphocyte activation gene-3 (LAG-3) decreases Th1-type immune responses in T-cells. LAG-3 expression is significantly induced in the lungs of ma
Externí odkaz:
https://doaj.org/article/f601410534d047899879c97264b15662
Autor:
Riley J. Mangan, M. Anthony Moody, Kan Luo, Erika L. Kunz, Christopher B. Fox, Alan D. Curtis, Hannah L. Itell, Shukhang Li, Kevin Wiehe, Mark A. Tomai, Kristina De Paris, Kenneth D. Cronin, Koen K. A. Van Rompay, Genevieve G. Fouda, Papa K Morgan-Asiedu, Holly Heimsath, S. Munir Alam, Michael G. Hudgens, Stella J. Berendam, Joshua A Eudailey, Bonnie L. Phillips, Sallie R. Permar
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0256885 (2021)
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 12 (2021)
PLoS ONE
Different HIV vaccine regimens elicit distinct plasma antibody responses in both human and nonhuman primate models. Previous studies in human and non-human primate infants showed that adjuvants influenced the quality of plasma antibody responses indu
Autor:
Muhammad H. Ahsan, Bonnie L. Phillips, Shabaana A. Khader, Moisés Selman, Smriti Mehra, Deepak Kaushal
Publikováno v:
The American Journal of Pathology. 185(3):820-833
Mycobacterium tuberculosis (MTB) is a highly successful pathogen because of its ability to persist in human lungs for long periods of time. MTB modulates several aspects of the host immune response. Lymphocyte-activation gene 3 (LAG3) is a protein wi
Autor:
Taylor W. Foreman, Smriti Mehra, Tianhua Niu, Uma S. Gautam, Allison N. Bucsan, Nadia A. Golden, Bonnie L. Phillips, Deepak Kaushal
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0180413 (2017)
PLoS ONE, Vol 12, Iss 9, p e0180413 (2017)
CD4+ T-cell mediated Th1 immune responses are critical for immunity to TB. The immunomodulatory protein, lymphocyte activation gene-3 (LAG-3) decreases Th1-type immune responses in T-cells. LAG-3 expression is significantly induced in the lungs of ma
Autor:
Uma S. Gautam, Muhammad H. Ahsan, Smriti Mehra, Shabaana A. Khader, Toidi Adekambi, Nadia A. Golden, Kasi E. Russell-Lodrigue, Peter J. Didier, Xavier Alvarez, James Blanchard, Taylor W. Foreman, Ann-Marie Johnson, Javier Rangel-Moreno, Chad J. Roy, Deepak Kaushal, Jyothi Rengarajan, Lara A. Doyle, Andrew A. Lackner, Bonnie L. Phillips
Publikováno v:
Nature Communications
Tuberculosis (TB) is a global pandaemic, partially due to the failure of vaccination approaches. Novel anti-TB vaccines are therefore urgently required. Here we show that aerosol immunization of macaques with the Mtb mutant in SigH (MtbΔsigH) result