Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bonnie L. Barrilleaux"'
Autor:
Bonnie L Barrilleaux, Dana Burow, Sarah H Lockwood, Abigail Yu, David J Segal, Paul S Knoepfler
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101151 (2014)
The transcription factor Miz-1 can either activate or repress gene expression in concert with binding partners including the Myc oncoprotein. The genomic binding of Miz-1 includes both core promoters and more distal sites, but the preferred DNA bindi
Externí odkaz:
https://doaj.org/article/3c90ecefd8224e8186338daae5bde6b2
Autor:
Paul S. Knoepfler, Craig Steward, Benjamin T. K. Yuen, Catherine T. Le, Jeanelle Ariza, Kayla Horton-Sparks, Ashley McDonough, Priyanka Somanath, Verónica Martínez-Cerdeño, Bonnie L. Barrilleaux
Publikováno v:
Stem cells and development. 26(19)
Human pluripotent stem cells (hPSC) have great clinical potential through the use of their differentiated progeny, a population in which there is some concern over risks of tumorigenicity or other unwanted cellular behavior due to residual hPSC. Prec
Autor:
Rebecca Cotterman, Bonnie L. Barrilleaux, Paul S. Knoepfler, Kelly M. Bush, Benjamin T. K. Yuen
Publikováno v:
Development. 141:3483-3494
The histone variant H3.3 is involved in diverse biological processes, including development, transcriptional memory and transcriptional reprogramming, as well as diseases, including most notably malignant brain tumors. Recently, we developed a knocko
Publikováno v:
Cell Stem Cell. 9(2):103-111
Induced pluripotent stem cells (iPSCs) hold great promise for autologous cell therapies, but significant roadblocks remain to translating iPSCs to the bedside. For example, concerns about the presumed autologous transplantation potential of iPSCs hav
Autor:
Paul S. Knoepfler, Abigail S. Yu, Sarah H. Lockwood, Dana A. Burow, Bonnie L. Barrilleaux, David J. Segal
Publikováno v:
PLoS ONE
PloS one, vol 9, iss 7
PLoS ONE, Vol 9, Iss 7, p e101151 (2014)
PloS one, vol 9, iss 7
PLoS ONE, Vol 9, Iss 7, p e101151 (2014)
The transcription factor Miz-1 can either activate or repress gene expression in concert with binding partners including the Myc oncoprotein. The genomic binding of Miz-1 includes both core promoters and more distal sites, but the preferred DNA bindi
Autor:
John W. Riggs, Bonnie L. Barrilleaux, Benjamin T. K. Yuen, Rebecca Cotterman, Henriette O'Geen, Kelly M. Bush, Paul S. Knoepfler
Publikováno v:
Bush, Kelly M; Yuen, Benjamin TK; Barrilleaux, Bonnie L; Riggs, John W; O’Geen, Henriette; Cotterman, Rebecca F; et al.(2013). Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development. Epigenetics & Chromatin, 6(1), 7. doi: http://dx.doi.org/10.1186/1756-8935-6-7. Retrieved from: http://www.escholarship.org/uc/item/4c96g6pw
Epigenetics & Chromatin
Epigenetics & Chromatin
Background The histone variant H3.3 plays key roles in regulating chromatin states and transcription. However, the role of endogenous H3.3 in mammalian cells and during development has been less thoroughly investigated. To address this gap, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e771a9ac0487438db7c8782cffa3c17c
http://www.escholarship.org/uc/item/4c96g6pw
http://www.escholarship.org/uc/item/4c96g6pw
Publikováno v:
The Myc Gene ISBN: 9781627034289
Myc and N-Myc have widespread impacts on the chromatin state within cells, both in a gene-specific and genome-wide manner. Our laboratory uses functional genomic methods including chromatin immunoprecipitation (ChIP), ChIP-chip, and, more recently, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d448dbfe2b522114a917793d5f71f2f
https://doi.org/10.1007/978-1-62703-429-6_9
https://doi.org/10.1007/978-1-62703-429-6_9
Autor:
Kelly M. Bush, John W. Riggs, Vanessa Chan, Bonnie L. Barrilleaux, Natasha Varlakhanova, Paul S. Knoepfler
Induced pluripotent stem cells (iPSCs) have the potential for creating patient-specific regenerative medicine therapies, but the links between pluripotency and tumorigenicity raise important safety concerns. More specifically, the methods employed fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f874b0a2341c84d9fdde27f44eb92c74
https://europepmc.org/articles/PMC3528096/
https://europepmc.org/articles/PMC3528096/
Autor:
Katie C. Russell, Bonnie L. Barrilleaux, Michelle Lacey, Kim C. O'Connor, Kristin E. Meyertholen, Donald G. Phinney
Publikováno v:
BMC Proceedings, Vol 5, Iss Suppl 8, p O14 (2011)
BMC Proceedings
BMC Proceedings
Background The regenerative capacity of mesenchymal stem cells (MSCs) is contingent on their content of multipotent progenitors [1]. Despite its importance to the efficacy of MSC therapies, the clonal heterogeneity of MSCs remains poorly defined. To
Publikováno v:
Journal of Visualized Experiments : JoVE
Stem and tumor cell biology studies often require viral transduction of human cells with known or suspected oncogenes, raising major safety issues for laboratory personnel. Pantropic lentiviruses, such as the commonly used VSV-G pseudotype, are a val