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pro vyhledávání: '"Bonnie L Mangold"'
Autor:
Edwin Bernard Villhauer, Thomas Edward Hughes, John A Brinkman, Manisha Mone, Bonnie L Mangold, Mary E Russell, Goli B Naderi, Stephen Craig Weldon, Beth E. Dunning
Publikováno v:
Journal of Medicinal Chemistry. 45:2362-2365
Dipeptidyl peptidase IV (DPP-IV) inhibition has the potential to become a valuable therapy for type 2 diabetes. We report the first use of solid-phase synthesis in the discovery of a new DPP-IV inhibitor class and a solution-phase synthesis that is p
Autor:
Beth E. Dunning, John A Brinkman, Bonnie L Mangold, Thomas Edward Hughes, Kapa Prasad, Edwin Bernard Villhauer, Bryan Burkey, Goli B Naderi, Mary E Russell
Publikováno v:
Journal of medicinal chemistry. 46(13)
Dipeptidyl peptidase IV (DPP-IV) inhibition has the potential to become a valuable therapy for type 2 diabetes. The synthesis and structure-activity relationship of a new DPP-IV inhibitor class, N-substituted-glycyl-2-cyanopyrrolidines, are described
Autor:
Patrick E. Hanna, Bonnie L Mangold
Publikováno v:
Chemischer Informationsdienst. 13