Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bonnie L Lyons"'
Autor:
Vishnu Hosur, Melissa L Cox, Lisa M Burzenski, Rebecca L Riding, Lynn Alley, Bonnie L Lyons, Anoop Kavirayani, Kimberly A Martin, Gregory A Cox, Kenneth R Johnson, Leonard D Shultz
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53426 (2013)
"Hairpatches" (Hpt) is a naturally occurring, autosomal semi-dominant mouse mutation. Hpt/Hpt homozygotes die in utero, while Hpt/+ heterozygotes exhibit progressive renal failure accompanied by patchy alopecia. This mutation is a model for the rare
Externí odkaz:
https://doaj.org/article/ce5a049eec354227b84f820d0d6f83e4
Autor:
Bonnie L. Lyons, Juan Antonio Aguilar-Pimentel, Colin McKerlie, Sara Wells, Michelle Stewart, Eleanor Herbert, John R. Seavitt, Rosalinda A Doty, Jean-Paul Wiegand, Liane Hobson, Ann M Flenniken, Lauryl M. J. Nutter, Brenda Kick, Dawei Qu, Jacqueline K. White, Martin Hrabe de Angelis, Marie Hutchison, Mary E Dickinson, Cheryl L. Scudamore
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0230162 (2020)
PLoS ONE 15:e0230162 (2020)
PLoS ONE
PLoS ONE 15:e0230162 (2020)
PLoS ONE
Dislocation in hindlimb tarsals are being observed at a low, but persistent frequency in adult male mice from C57BL/6N substrains. Clinical signs included a sudden onset of mild to severe unilateral or bilateral tarsal abduction, swelling, abnormal h
Autor:
Bonnie L Lyons, Holly S. Savage, Kevin G Kane, Jennifer L Ryan, Stacey J. Sukoff Rizzo, Ron Korstanje
Publikováno v:
Endocrinology. 158:2707-2712
Previous studies with continuous glucose monitoring in mice have been limited to several days or weeks, with the mouse's physical attachment to the equipment affecting behavior and measurements. In the current study, we measured blood glucose and bod
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
Gain-of-function (GOF) mutations in RHBDF2 cause tylosis. Patients present with hyperproliferative skin, and keratinocytes from tylosis patients’ skin show an enhanced wound-healing phenotype. The curly bare mouse model of tylosis, carrying a GOF m
Autor:
James R, Fahey, Bonnie L, Lyons, Haiyan L, Olekszak, Anthony J, Mourino, Jeremy J, Ratiu, Jeremy J, Racine, Harold D, Chapman, David V, Serreze, Dina L, Baker, N Ken, Hendrix
Publikováno v:
Comparative medicine. 67(4)
Segmented filamentous bacterium (SFB) a gram-positive, anaerobic, and intestinal commensal organism directly influences the development of Th17 helper cells in the small intestine of mice. In NOD mice, SFB colonization interferes with the development
Autor:
Bonnie L. Lyons, Gregory A. Cox, Leonard D. Shultz, Lisa Carney, Vishnu Hosur, Bruce Gott, Anoop Kavirayani, Jennifer Riefler
Publikováno v:
Cancer Genetics. 205:232-241
While researchers are yet to establish a link a between muscular dystrophy (MD) and sarcomas in human patients, literature suggests that MD genes dystrophin and dysferlin act as tumor suppressor genes in mouse models of MD. For instance, dystrophin d
Autor:
Priscilla W. Lane, Leonard D. Shultz, Belinda S. Harris, Joachim Thiery, Bonnie L. Lyons, Leah Rae Donahue, Joseph E. Italiano, Oded Foreman, Roderick T. Bronson, Bruce Gott, Jonathan N. Thon, Kenneth R. Johnson, Henning Wittenburg, Uta Ceglarek, Lisa M. Burzenski, Thomas H. Chase
Publikováno v:
Blood. 115:1267-1276
The spontaneous mouse mutation “thrombocytopenia and cardiomyopathy” (trac) causes macrothrombocytopenia, prolonged bleeding times, anemia, leukopenia, infertility, cardiomyopathy, and shortened life span. Homozygotes show a 20-fold decrease in p
Autor:
Bonnie L. Lyons, Bruce Gott, Oded Foreman, Aldo A. Rossini, David Miller, William Fodor, J Laning, Dale L. Greiner, Lisa M. Burzenski, Todd Pearson, Marie A. King, Leonard D. Shultz, Amy Cuthbert
Publikováno v:
Clinical and Experimental Immunology. 154:270-284
Immunodeficient hosts engrafted with human lymphohaematopoietic cells hold great promise as a preclinical bridge for understanding human haematopoiesis and immunity. We now describe a new immunodeficient radioresistant non-obese diabetic mice (NOD) s
Autor:
Dale L. Greiner, Leonard D. Shultz, Aldo A. Rossini, Bruce Gott, Bonnie L. Lyons, Lisa J. Giassi, Lisa Carney, Todd Pearson, Marie A. King
Publikováno v:
Annals of the New York Academy of Sciences. 1103:77-89
There are many rodent models of autoimmune diabetes that have been used to study the pathogenesis of human type 1 diabetes (T1D), including the non-obese diabetic (NOD) mouse, the biobreeding (BB) rat, and the transgenic mouse models. However, mice a
Autor:
Bonnie L. Lyons, Linda L. Waterman
Publikováno v:
Current Protocols in Mouse Biology
Personnel performing surgery on mice commonly lack formal medical training and most training in mouse surgery focuses on the mechanical skills required for a procedure with less emphasis on perioperative techniques. Consequently, a basic concept that