Zobrazeno 1 - 10 of 49 pro vyhledávání: '"Bonnie L, King"'
1
Akademický článek
Clinicopathologic features, genomic profiles and outcomes of younger vs. older Chinese hormone receptor-positive (HR+)/HER2-negative (HER2-) metastatic breast cancer patients
Autor: Jinhao Wang, Yaxin Liu, Yuehua Liang, Yue Zhang, Hang Dong, Tiantian Zheng, Jianjun Yu, Pan Du, Shidong Jia, Bonnie L. King, Jing Wang, Xiaoran Liu, Huiping Li
Publikováno v: Frontiers in Oncology, Vol 13 (2023)
BackgroundPoor outcomes have been widely reported for younger vs. older breast cancer patients, but whether this is due to age itself or the enrichment of aggressive clinical features remains controversial. We have evaluated the clinicopathologic cha
Externí odkaz: https://doaj.org/article/778598ddfb964f7b8b707984f1035b1b
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2
Akademický článek
Identification of mutation patterns and circulating tumour DNA-derived prognostic markers in advanced breast cancer patients
Autor: Hao Liao, Jiayang Zhang, Tiantian Zheng, Xiaoran Liu, Jianxin Zhong, Bin Shao, Xiaoxi Dong, Xiaohong Wang, Pan Du, Bonnie L. King, Shidong Jia, Jianjun Yu, Huiping Li
Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background The correlations between circulating tumour DNA (ctDNA)-derived genomic markers and treatment response and survival outcome in Chinese patients with advanced breast cancer (ABC) have not been extensively characterized. Methods Blo
Externí odkaz: https://doaj.org/article/cbc87586bb7c44a498e82a393fbb682b
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3
Akademický článek
Dynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer
Autor: Winston Tan, Tiantian Zheng, Amy Wang, Joanna Roacho, Seng Thao, Pan Du, Shidong Jia, Jianjun Yu, Bonnie L. King, Manish Kohli
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Docetaxel chemotherapy is a standard treatment option for metastatic castrate resistant prostate cancer (mCRPC) patients. To date, the genomic perturbations underlying the emergence of resistance in mCRPC patients during chemotherapy treatme
Externí odkaz: https://doaj.org/article/0d9f684fec4f46d5a0be84ed41428824
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4
Akademický článek
Circulating Cell-Free DNA-Based Detection of Tumor Suppressor Gene Copy Number Loss and Its Clinical Implication in Metastatic Prostate Cancer
Autor: Xiaoxi Dong, Tiantian Zheng, Minhua Zhang, Chao Dai, Lili Wang, Lei Wang, Ruipeng Zhang, Yuan Long, Danyi Wen, Feng Xie, Yue Zhang, Yong Huang, Jianguo Dong, Huan Liu, Pan Du, Bonnie L. King, Winston Tan, Shidong Jia, Chris X. Lu, Manish Kohli, Haitao Wang, Jianjun Yu
Publikováno v: Frontiers in Oncology, Vol 11 (2021)
Current liquid biopsy assays lack sufficient sensitivity to detect copy number loss, which limits the interrogation of critical tumor suppressor gene deletions during cancer progression and treatment. Here we describe a liquid biopsy assay with impro
Externí odkaz: https://doaj.org/article/8d43e9fdf19046549c4e88294af7337c
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6
Akademický článek
Local estrogen axis in the human bone microenvironment regulates estrogen receptor-positive breast cancer cells
Autor: Derek F. Amanatullah, John S. Tamaresis, Pauline Chu, Michael H. Bachmann, Nhat M. Hoang, Deborah Collyar, Aaron T. Mayer, Robert B. West, William J. Maloney, Christopher H. Contag, Bonnie L. King
Publikováno v: Breast Cancer Research, Vol 19, Iss 1, Pp 1-16 (2017)
Abstract Background Approximately 70% of all breast cancers express the estrogen receptor, and are regulated by estrogen. While the ovaries are the primary source of estrogen in premenopausal women, most breast cancer is diagnosed following menopause
Externí odkaz: https://doaj.org/article/19b0a1c374384976a50affc318f9b6a8
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