Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Bonnie L, Hylander"'
Autor:
Minhui Chen, Guanxi Qiao, Bonnie L. Hylander, Hemn Mohammadpour, Xiang-Yang Wang, John R. Subjeck, Anurag K. Singh, Elizabeth A. Repasky
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Abscopal responses in patients and preclinical models following radiation therapy are rare. Here the authors show that, in murine tumor models, reducing adrenergic stress or β2-adrenergic receptor signalling not only improves control of the irradiat
Externí odkaz:
https://doaj.org/article/bf540c3fc9a8411c9f4089714a3b4c2c
Publikováno v:
International Journal of Hyperthermia, Vol 36, Iss 0, Pp 83-89 (2019)
There is substantial research being conducted on the relationships between the gut microbiome, the immune response and health and disease. Environmental temperature and heat stress are known to modify the gut microbiome. Changes in core temperature h
Externí odkaz:
https://doaj.org/article/147018a80dfa48f4bd23ea087d30fd6e
Publikováno v:
Animals, Vol 12, Iss 3, p 371 (2022)
Mice are the most common animal used to study disease, but there are real concerns about the reproducibility of many of these experiments. This review discusses how several different sources of chronic stress can directly impact experimental outcomes
Externí odkaz:
https://doaj.org/article/785ae86b7e924f8ba1a8d296afd50eb8
Autor:
Elizabeth A. Repasky, Joseph J. Barbi, Bonnie L. Hylander, Mark J. Bucsek, Cameron R. MacDonald, Hemn Mohammadpour, Minhui Chen, Guanxi Qiao
Metabolic dysfunction and exhaustion in tumor-infiltrating T cells have been linked to ineffectual antitumor immunity and the failure of immune checkpoint inhibitor therapy. We report here that chronic stress plays a previously unrecognized role in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d146c388aad554791599fa240ff3dc1
https://doi.org/10.1158/2326-6066.c.6550284.v1
https://doi.org/10.1158/2326-6066.c.6550284.v1
Autor:
Elizabeth A. Repasky, Joseph J. Barbi, Bonnie L. Hylander, Mark J. Bucsek, Cameron R. MacDonald, Hemn Mohammadpour, Minhui Chen, Guanxi Qiao
Supplementary Figures 1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5a0fef03c4032acbebea221da6a69d
https://doi.org/10.1158/2326-6066.22543479
https://doi.org/10.1158/2326-6066.22543479
Autor:
Elizabeth A. Repasky, Joseph J. Barbi, Bonnie L. Hylander, Mark J. Bucsek, Cameron R. MacDonald, Hemn Mohammadpour, Minhui Chen, Guanxi Qiao
Supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5328d2b8f32112fccd9a3f08af0eeb
https://doi.org/10.1158/2326-6066.22543476.v1
https://doi.org/10.1158/2326-6066.22543476.v1
Autor:
Robert M. Straubinger, Wen Wee Ma, Elizabeth A. Repasky, Bonnie L. Hylander, Rosemarie F. Pitoniak, Ninfa L. Straubinger, Tista Roy Chaudhuri
Supplemental Figure S1: Histological characteristics of human pancreatic adenocarcinoma #18269 Supplemental Figure S2: Treatment effects on histology of human pancreatic adenocarcinoma #18269 Supplemental Figure S3: Gross morphology of #18269 tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cfc39d2cd57a8e0a128fb19253ab11
https://doi.org/10.1158/1535-7163.22503594.v1
https://doi.org/10.1158/1535-7163.22503594.v1
Autor:
Elizabeth A. Repasky, Bonnie L. Hylander, Scott I. Abrams, Kristopher Attwood, Michelle N. Messmer, Jason W.-L. Eng, Kathleen M. Kokolus, Haichao Liu, Brian Niedzwecki, Lauren Evans, Thejaswini Giridharan, Cameron R. MacDonald, Guanxi Qiao, Mark J. Bucsek
This data shows that housing mice at 30 degrees Celsius improves the efficacy of anti-PD-1 in both 4T1 and B16-OVA tumor-bearing mice indicating that cool housing temperatures (22 degrees C) impairs the efficacy of anti-PD-1 in murine tumor models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600baffff9aca5eeba91cd8561516aec
https://doi.org/10.1158/0008-5472.22414770
https://doi.org/10.1158/0008-5472.22414770
Autor:
Elizabeth A. Repasky, Bonnie L. Hylander, Scott I. Abrams, Kristopher Attwood, Michelle N. Messmer, Jason W.-L. Eng, Kathleen M. Kokolus, Haichao Liu, Brian Niedzwecki, Lauren Evans, Thejaswini Giridharan, Cameron R. MacDonald, Guanxi Qiao, Mark J. Bucsek
The immune context of tumors has significant prognostic value and is predictive of responsiveness to several forms of therapy, including immunotherapy. We report here that CD8+ T-cell frequency and functional orientation within the tumor microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aec282661638d66a258465c3d3cac9c3
https://doi.org/10.1158/0008-5472.c.6509076.v1
https://doi.org/10.1158/0008-5472.c.6509076.v1
Publikováno v:
Biochimie.