Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Bonnie L, Firestein"'
Autor:
Kate M. O’Neill, Erin D. Anderson, Shoutik Mukherjee, Srinivasa Gandu, Sara A. McEwan, Anton Omelchenko, Ana R. Rodriguez, Wolfgang Losert, David F. Meaney, Behtash Babadi, Bonnie L. Firestein
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-26 (2023)
Abstract Plasticity and homeostatic mechanisms allow neural networks to maintain proper function while responding to physiological challenges. Despite previous work investigating morphological and synaptic effects of brain-derived neurotrophic factor
Externí odkaz:
https://doaj.org/article/e1e5c43717a04baca95775a9fd22f1ed
Autor:
Kiran Deshpande, Keith R. Lange, William B. Stone, Christine Yohn, Naomi Schlesinger, Leonid Kagan, Albert J. Auguste, Bonnie L. Firestein, Luigi Brunetti
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and the resulting Coronavirus disease 2019 emerged in late 2019 and is responsible for significant morbidity and mortality worldwide. A hallmark of severe COVID‐19
Externí odkaz:
https://doaj.org/article/e052e2468a4e4ade868bc6b503dad771
Autor:
Ana R. Rodriguez, Erin D. Anderson, Kate M. O’Neill, Przemyslaw P. McEwan, Nicholas F. Vigilante, Munjin Kwon, Barbara F. Akum, Tamara M. Stawicki, David F. Meaney, Bonnie L. Firestein
Publikováno v:
Network Neuroscience, Vol 5, Iss 1, Pp 166-197 (2021)
AbstractCytosolic PSD-95 interactor (cypin) regulates many aspects of neuronal development and function, ranging from dendritogenesis to synaptic protein localization. While it is known that removal of postsynaptic density protein-95 (PSD-95) from th
Externí odkaz:
https://doaj.org/article/1fec7c349a124b99bff18e67c059684b
Autor:
Chen Liang, Damien Carrel, Nisha K. Singh, Liam L. Hiester, Isabelle Fanget, Hyuck Kim, Bonnie L. Firestein
Publikováno v:
ASN Neuro, Vol 14 (2022)
Neuronal migration and dendritogenesis are dependent on dynamic changes to the microtubule (MT) network. Among various factors that regulate MT dynamics and stability, post-translational modifications (PTMs) of MTs play a critical role in conferring
Externí odkaz:
https://doaj.org/article/6da040f9ace9481e93992890c6504a02
Autor:
Chelsea Schiliro, Bonnie L. Firestein
Publikováno v:
Cells, Vol 11, Iss 22, p 3593 (2022)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/c32a46e0176f496fbb1720428f1bbc60
Autor:
Daniel Sumetsky, James Y. Jiang, Marina A. Ayad, Timothy Mahon, Audrey Menaesse, Marina M. Cararo-Lopes, Mihir V. Patel, Bonnie L. Firestein, Nada N. Boustany
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
We utilize a cost-effective frequency-domain fluorescence lifetime imaging microscope to measure the phase lifetime of mTFP1 in mTFP1-mVenus fluorescence resonance energy transfer (FRET) constructs relevant to the VinTS molecular tension probe. Our d
Externí odkaz:
https://doaj.org/article/02cb175071fb4e31b50ad765cf58f956
Publikováno v:
Frontiers in Computational Neuroscience, Vol 15 (2021)
Traumatic brain injury is a devastating public health problem, the eighth leading cause of death across the world. To improve our understanding of how injury at the cellular scale affects neural circuit function, we developed a protocol to precisely
Externí odkaz:
https://doaj.org/article/a2439ce7ba64497294857d8061d637bb
Autor:
Przemyslaw Swiatkowski, Emily Sewell, Eric S. Sweet, Samantha Dickson, Rachel A. Swanson, Sara A. McEwan, Nicholas Cuccolo, Mark E. McDonnell, Mihir V. Patel, Nevin Varghese, Barclay Morrison, Allen B. Reitz, David F. Meaney, Bonnie L. Firestein
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 13-25 (2018)
Cytosolic PSD-95 interactor (cypin), the primary guanine deaminase in the brain, plays key roles in shaping neuronal circuits and regulating neuronal survival. Despite this pervasive role in neuronal function, the ability for cypin activity to affect
Externí odkaz:
https://doaj.org/article/8095552ee2c146b2a82d2af90ff6cb2a
Autor:
Przemyslaw Swiatkowski, Ina Nikolaeva, Gaurav Kumar, Avery Zucco, Barbara F. Akum, Mihir V. Patel, Gabriella D’Arcangelo, Bonnie L. Firestein
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Glutamate-induced excitotoxicity, mediated by overstimulation of N-methyl-D-aspartate (NMDA) receptors, is a mechanism that causes secondary damage to neurons. The early phase of injury causes loss of dendritic spines and changes to synaptic
Externí odkaz:
https://doaj.org/article/187734828ebb47e29e21b6060cf27c55
Autor:
Siddhant Kumarapuram, Ansley J. Kunnath, Anton Omelchenko, Nada N. Boustany, Bonnie L. Firestein
Publikováno v:
Annals of Biomedical Engineering. 50:1116-1133