Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Bonnie K, Harrington"'
Autor:
Alexander R. Marr, Madeline Halpin, Dominique L. Corbin, Yerdanos Asemelash, Steven Sher, Britten K. Gordon, Ethan C. Whipp, Shaneice Mitchell, Bonnie K. Harrington, Shelley Orwick, Samon Benrashid, Virginia M. Goettl, Vedat Yildiz, Andrew D. Mitchell, Olivia Cahn, Alice S. Mims, Karilyn T. M. Larkin, Meixao Long, James Blachly, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-21 (2024)
Abstract Acute myeloid leukemia (AML) is a highly aggressive hematologic cancer with poor survival across a broad range of molecular subtypes. Development of efficacious and well-tolerable therapies encompassing the range of mutations that can arise
Externí odkaz:
https://doaj.org/article/e0b183ba829743ce9571ebd758015fbb
Autor:
Zachary A. Hing, Janek S. Walker, Ethan C. Whipp, Lindsey Brinton, Matthew Cannon, Pu Zhang, Steven Sher, Casey B. Cempre, Fiona Brown, Porsha L. Smith, Claudio Agostinelli, Stefano A. Pileri, Jordan N. Skinner, Katie Williams, Hannah Phillips, Jami Shaffer, Larry P. Beaver, Alexander Pan, Kyle Shin, Charles T. Gregory, Gulcin H. Ozer, Selen A. Yilmaz, Bonnie K. Harrington, Amy M. Lehman, Lianbo Yu, Vincenzo Coppola, Pearlly Yan, Peggy Scherle, Min Wang, Philip Pitis, Chaoyi Xu, Kris Vaddi, Selina Chen-Kiang, Jennifer Woyach, James S. Blachly, Lapo Alinari, Yiping Yang, John C. Byrd, Robert A. Baiocchi, Bradley W. Blaser, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Richter’s Transformation is a treatment-resistant and fatal progression from Chronic Lymphocytic Leukemia (CLL) to an aggressive lymphoma. Here, the authors show that PRMT5 is upregulated months prior to and after transformation, PRMT5 overexpressi
Externí odkaz:
https://doaj.org/article/69b4b26dffde485788921c4c7e1fc14a
Autor:
Yo-Ting Tsai, Aparna Lakshmanan, Amy Lehman, Bonnie K. Harrington, Fabienne McClanahan Lucas, Minh Tran, Ellen J. Sass, Meixiao Long, Alan D. Flechtner, Florinda Jaynes, Krista La Perle, Vincenzo Coppola, Gerard Lozanski, Natarajan Muthusamy, John C. Byrd, Michael R. Grever, David M. Lucas
Publikováno v:
Blood Advances, Vol 1, Iss 24, Pp 2147-2160 (2017)
Abstract: Mutated mitogen-activated protein kinase (MAPK) pathway components promote tumor survival, proliferation, and immune evasion in solid tumors. MAPK mutations occur in hematologic cancers as well, but their role is less clear and few models a
Externí odkaz:
https://doaj.org/article/c6e0f46b0f7340d6824ced467f0fcaeb
Autor:
Jennifer A. Woyach, John C. Byrd, Amy J. Johnson, Brian Schwartz, Giovanni Abbadessa, Sudharshan Eathiraj, Rosa Lapalombella, Deepa Sampath, Amy M. Lehman, Leslie Andritsos, Kami Maddocks, Farrukh T. Awan, Kerry A. Rogers, Bonnie K. Harrington, Minh Tran, Virginia M. Goettl, Catherine A. Fabian, Elizabeth M. Muhowski, J.T. Greene, Lisa L. Smith, Rose Mantel, Sean D. Reiff
methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7ef9f6bcdee97cb0b821e7d945632a
https://doi.org/10.1158/2159-8290.22531706
https://doi.org/10.1158/2159-8290.22531706
Autor:
Jennifer A. Woyach, John C. Byrd, Amy J. Johnson, Brian Schwartz, Giovanni Abbadessa, Sudharshan Eathiraj, Rosa Lapalombella, Deepa Sampath, Amy M. Lehman, Leslie Andritsos, Kami Maddocks, Farrukh T. Awan, Kerry A. Rogers, Bonnie K. Harrington, Minh Tran, Virginia M. Goettl, Catherine A. Fabian, Elizabeth M. Muhowski, J.T. Greene, Lisa L. Smith, Rose Mantel, Sean D. Reiff
Suppl Figure 2 with legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385f18aeea68dabb4dbbaac94338f38c
https://doi.org/10.1158/2159-8290.22531715.v1
https://doi.org/10.1158/2159-8290.22531715.v1
Autor:
Jennifer A. Woyach, John C. Byrd, Amy J. Johnson, Brian Schwartz, Giovanni Abbadessa, Sudharshan Eathiraj, Rosa Lapalombella, Deepa Sampath, Amy M. Lehman, Leslie Andritsos, Kami Maddocks, Farrukh T. Awan, Kerry A. Rogers, Bonnie K. Harrington, Minh Tran, Virginia M. Goettl, Catherine A. Fabian, Elizabeth M. Muhowski, J.T. Greene, Lisa L. Smith, Rose Mantel, Sean D. Reiff
Suppl Table 2 with legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0535de0493bbdaa7fa5937f5929b5676
https://doi.org/10.1158/2159-8290.22531709
https://doi.org/10.1158/2159-8290.22531709
Autor:
Jennifer A. Woyach, John C. Byrd, Amy J. Johnson, Brian Schwartz, Giovanni Abbadessa, Sudharshan Eathiraj, Rosa Lapalombella, Deepa Sampath, Amy M. Lehman, Leslie Andritsos, Kami Maddocks, Farrukh T. Awan, Kerry A. Rogers, Bonnie K. Harrington, Minh Tran, Virginia M. Goettl, Catherine A. Fabian, Elizabeth M. Muhowski, J.T. Greene, Lisa L. Smith, Rose Mantel, Sean D. Reiff
Suppl Table 1 with legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3f15fd95f429da4a0774e78dceb823
https://doi.org/10.1158/2159-8290.22531712
https://doi.org/10.1158/2159-8290.22531712
Autor:
Jennifer A. Woyach, John C. Byrd, Amy J. Johnson, Brian Schwartz, Giovanni Abbadessa, Sudharshan Eathiraj, Rosa Lapalombella, Deepa Sampath, Amy M. Lehman, Leslie Andritsos, Kami Maddocks, Farrukh T. Awan, Kerry A. Rogers, Bonnie K. Harrington, Minh Tran, Virginia M. Goettl, Catherine A. Fabian, Elizabeth M. Muhowski, J.T. Greene, Lisa L. Smith, Rose Mantel, Sean D. Reiff
Suppl Figure 1 with legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e90253ac6021f01d7ba67e84e2235b6
https://doi.org/10.1158/2159-8290.22531718.v1
https://doi.org/10.1158/2159-8290.22531718.v1
Autor:
Jennifer A. Woyach, Adrian Wiestner, Brian J. Lannutti, Amy J. Johnson, Roger Ulrich, Allard Kaptein, Raquel Izumi, John C. Byrd, Todd Covey, Dolors Colomer, Bonnie K. Harrington, Fabienne McClanahan, Lisa L. Smith, Rose Mantel, Fanny Krantz, Michael Gulrajani, Helena Mora-Jensen, Carsten U. Niemann, Arnau Montraveta, Sarah E.M. Herman
Supplementary Figure S5: Acalabrutinib demonstrates similar changes in proliferation and tumor burden in the CLL xenograft mouse model as ibrutinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c6b24397ba4d6b61ecbea462928663
https://doi.org/10.1158/1078-0432.22462839
https://doi.org/10.1158/1078-0432.22462839
Autor:
Jennifer A. Woyach, Rosa Lapalombella, John C. Byrd, Pearlly Yan, Danielle K. White, Ronni Wasmuth, Lisa L. Smith, Deepa Sampath, Rose Mantel, Parviz Kanga, Zachary A. Hing, Virginia M. Goettl, Ralf Bundschuh, Justin Breitbach, Lianbo Yu, Alexander Pan, Bonnie K. Harrington, Kerry A. Rogers, Fabienne Lucas
Purpose:Aberrant Myc expression is a major factor in the pathogenesis of aggressive lymphoma, and these lymphomas, while clinically heterogeneous, often are resistant to currently available treatments and have poor survival. Myc expression can also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5018b4badb203541096ba4b3eaff1e04
https://doi.org/10.1158/1078-0432.c.6528003.v1
https://doi.org/10.1158/1078-0432.c.6528003.v1