Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bonnie J. Mills"'
Autor:
Petr Krivorotko, Alexey Manikhas, Elena Poddubskaya, Dmitry Osinsky, Mamillapalli Gopichand, Alexander Vasilyev, Fedor Vladimirovich Moiseenko, Dmytro Trukhin, Ashley E. Alarcon-Rozas, Hryhoriy Bardakov, Tori Haynes, Jennifer Lai, Bonnie J. Mills
Publikováno v:
Journal of Clinical Oncology. 40:LBA511-LBA511
LBA511 Background: TX05 is being developed as a biosimilar to trastuzumab. We previously reported results of a Phase III study (TX05-03) comparing the efficacy and safety of TX05 to originator trastuzumab (TRA) in patients with HER2+ early breast can
Autor:
Amy D. Shapiro, Bonnie J. Mills, Martin Lee, Vijay Ramanan, Joseph M John, Edward D. Gomperts, Shashikant Apte, Ri Liesner, Utpal Chaudhuri
Publikováno v:
Blood. 120:2225-2225
Abstract 2225 Introduction IB1001 is a recombinant factor IX product being investigated for the treatment and prevention of bleeding in individuals with hemophilia B. Pharmacokinetics (PK) in adults (>12 years) demonstrated that IB1001 had results si
Autor:
Irena Sniecinski, George Somlo, James Raschko, James H. Doroshow, Steven A. Akman, Kim Margolin, Bonnie J. Mills, David Goldberg, Robert J. Morgan, Lucille Leong
Publikováno v:
Journal of immunotherapy : official journal of the Society for Biological Therapy. 11(1)
Interleukin-2 (IL-2) and gamma interferon (gamma-IFN) may be synergistic in inducing cell-mediated antitumor cytotoxicity. In order to determine the dose-limiting toxicities and define a maximum tolerated dose of these two agents in combination, we p
Autor:
Marcia Will, Isaac B. Weisfuse, Joel N. Kuritsky, Anthony A. Rayner, Stephen C. Hadler, Richard I. Fisher, David Parkinson, David J. Graham, Ruth A. Karron, Stephen M. Feinstone, Janice R Dutcher, Bonnie J. Mills, Alice Glover, Geoffrey R. Weiss, Michael B. Atkins, David R. Snydman
Publikováno v:
Europe PubMed Central
An outbreak of hepatitis A virus (HAV) infection occurred among cancer patients treated with interleukin-2 (IL-2) and lymphokine-activated killer (LAK) cells between July and September 1986 at six different clinical centers. Among 85 patients tested
Publikováno v:
The Journal of Immunology. 123:2518-2524
Vesicular stomatitis virus (VSV) is efficiently neutralized by normal, nonimmune human serum without the participation of antibody. Neutralization is complement-(C) dependent and requires the early-acting components of the classical pathway, C1, C4,
Autor:
Dennis D. Weisenburger, Lawrence W. Diamond, Bonnie J. Mills, Carl D. Winberg, Raymond L. Teplitz, Paula K. Berry, Henry Rappaport, Robert M. Bearman, Bharat N. Nathwani
Publikováno v:
American Journal of Hematology. 9:319-330
Cells isolated from four patients with prolymphocytic leukemia were evaluated by surface markers, cytogenetics, and flow microfluorometric analysis of cell size and DNA content. All four patients had B-cell markers with a high density of IgM, kappa t
Autor:
Bonnie J. Mills, Neil R. Cooper
Publikováno v:
The Journal of Immunology. 121:1549-1557
Normal human serum neutralized up to 5 logs10/ml of vesicular stomatitis virus (VSV) grown in hamster (BHK), mouse (L), or human (HFF) cell lines when equal volumes of virus (∼105 PFU/ml) and serum were incubated together for 30 min at 37°C. The n
Publikováno v:
Journal of immunological methods. 67(1)
Although conditioned medium (CM) from human lymphocytes or mononuclear cells is the most readily available source of interleukin-2 (IL-2) for human T cell culture, its IL-2 activity in our experience is inconsistent. It is likely that this is, at lea
Publikováno v:
Journal of clinical apheresis. 4(2-3)
Adoptive transfer of autologous lymphokine-activated killer cells (LAK) in conjunction with recombinant interleu-kin-2 (rIL-2) has been reported to produce significant regression in metastatic disease in patients with advanced cancer. In an effort to
Publikováno v:
Journal of immunological methods. 67(2)
A method for the facile removal of mitogens or inducers of lymphokine production from cell culture medium of stimulated cells is described. The technique is based on the covalent attachment of biotin to mitogen or inducer and the removal of the bioti