Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bonnie J. Bowdon"'
Autor:
Claudy J.-P. Mullon, Karen E. Dunleavy, Lois B. Allen, Debra C. Quenelle, Kathy A. Keith, Anne D. Brazier, Beth A. Taylor, Bonnie J. Bowdon, Reginald E. Harris
Publikováno v:
Antiviral Research. 35:123-129
We now report the confirmation of the work of Hollingshead et al. (1995) on development of a cell based hollow fiber (HF) system for evaluating potential anti-AIDS drugs in vivo using conventional mice rather than SCID mice. CD4+, CEM-SS cells infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e321b05ac9ae99f94f8992eaee3a8e
https://doi.org/10.1016/s0166-3542(97)00014-4
https://doi.org/10.1016/s0166-3542(97)00014-4
Autor:
Bonnie J. Bowdon, Robert Vince, S. A. Beers, William B. Parker, Phuong Truc T. Pham, John Kilama, Kathy A. Keith
Publikováno v:
Nucleosides and Nucleotides. 14:1703-1708
A series of 6-alkoxy and 6-alkylamino carbovir derivatives were synthesized in order to evaluate prodrug approaches to increased bioavailability of the anti-HIV agent, carbovir. All of the compounds were active against HIV with the N-alkyl derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc41b7bbc39f0f8462f23f0962cf9dfc
https://doi.org/10.1080/15257779508009751
https://doi.org/10.1080/15257779508009751
Autor:
John P. Bader, E. Lucile White, Bonnie J. Bowdon, Joseph L. Roberson, W. Don Decker, James B. McMahon, Tammy Antonucci, Valerie Fliakas-Boltz, Cathi A. Pyle, Hubert Barth, Michael R. Boyd, Robert W. Buckheit, David G. Nickell
Publikováno v:
Antiviral Research. 25:43-56
A series of benzothiadiazine derivatives were screened against the human immunodeficiency virus (HIV) and certain structure-activity relationships were defined for anti-HIV activity in this chemical class. The selected representative NSC 287474 was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c776a765c4fa882b09cf56eac5ea88
https://doi.org/10.1016/0166-3542(94)90092-2
https://doi.org/10.1016/0166-3542(94)90092-2
Autor:
Bonnie J. Bowdon, William B. Parker, Phuong Truc T. Pham, Robert Vince, Kathy A. Keith, John Kilama, S. A. Beers
Publikováno v:
ChemInform. 27
A series of 6-alkoxy and 6-alkylamino carbovir derivatives were synthesized in order to evaluate prodrug approaches to increased bioavailability of the anti-HIV agent, carbovir. All of the compounds were active against HIV with the N-alkyl derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::140d4dbd3d52e747f4e3965b9525dec4
https://doi.org/10.1002/chin.199608250
https://doi.org/10.1002/chin.199608250
Autor:
Karen Qualls-Goodwin, Bonnie J. Bowdon, William M. Shannon, Julie Germany-Decker, Robert W. Buckheit
Publikováno v:
Proceedings of the National Academy of Sciences. 89:8361-8365
A cocultivation assay system consisting of uninfected human T cells and cells chronically infected with human immunodeficiency virus type 1 has been used to investigate syncytium formation in short-term assays. Continuous treatment or short-term pret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae27a018fe0cc3535ea19d988584b422
https://doi.org/10.1073/pnas.89.17.8361
https://doi.org/10.1073/pnas.89.17.8361
Autor:
Bonnie J. Bowdon, William B. Parker, Robert Vince, L. Lee Bennett, Lucy M. Rose, William M. Shannon, Sue C. Shaddix
Publikováno v:
Antimicrobial agents and chemotherapy. 37(5)
Carbovir (CBV) [the (--)-enantiomer of the carbocyclic analog of 2',3'-dideoxy-2',3'-didehydroguanosine] is a potent inhibitor of human immunodeficiency virus type 1 (HIV) replication in vitro. We have characterized the metabolism of CBV and its effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6736c6f104f35d594966afc67e0933
https://pubmed.ncbi.nlm.nih.gov/7685993
https://pubmed.ncbi.nlm.nih.gov/7685993
Autor:
Theresa Gygi, William M. Shannon, Bonnie J. Bowdon, Kathy A. Keith, Kwan Y. Hui, Mei-Huei T. Lai, Joseph V. Manetta
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 5(11)
Synthetic peptides described as dog renin inhibitors were found to effectively inhibit the aspartyl protease of human immunodeficiency virus (HIV). The selection of oligopeptides for the HIV protease inhibition study was based on 1) the current strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32595667ac4416e8ba94ecce5914db77
https://pubmed.ncbi.nlm.nih.gov/1868985
https://pubmed.ncbi.nlm.nih.gov/1868985
Publikováno v:
Biochemical Pharmacology. 35:4106-4109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89238507b987ef8b5767d156396e078f
https://doi.org/10.1016/0006-2952(86)90036-5
https://doi.org/10.1016/0006-2952(86)90036-5
Publikováno v:
Experimental Biology and Medicine. 126:903-906
SummaryThe cell cycles of Leukemia L1210 cells proliferating in mice after serial transplantation, proliferating in mice following inoculation of cultured cells, and proliferating in vitro in spinner cultures have been examined by the method of waves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f05eb06e40c7c59c085faa8468ad0184
https://doi.org/10.3181/00379727-126-32601
https://doi.org/10.3181/00379727-126-32601
Autor:
Bonnie J. Bowdon, Glynn P. Wheeler
Publikováno v:
Journal of Biological Chemistry. 241:1114-1121
Experimental evidence indicates that an analogue of nicotinamide adenine dinucleotide in which the adenine moiety is replaced by 2,6-diaminopurine is formed when cultured mammalian cells are grown in the presence of 2,6-diaminopurine. It is also like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d94ae58028dc2a36b24d65e2e8eae6
https://doi.org/10.1016/s0021-9258(18)96809-2
https://doi.org/10.1016/s0021-9258(18)96809-2