Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bonnie J, Cuthbert"'
Autor:
Steven J. Jensen, Bonnie J. Cuthbert, Fernando Garza-Sánchez, Colette C. Helou, Rodger de Miranda, Celia W. Goulding, Christopher S. Hayes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Advanced glycation end-products (AGE) are a pervasive form of protein damage implicated in the pathogenesis of neurodegenerative disease, atherosclerosis and diabetes mellitus. Glycation is typically mediated by reactive dicarbonyl compounds
Externí odkaz:
https://doaj.org/article/aacecc95082d4d89b0ef2948263be60d
Autor:
Rodger de Miranda, Bonnie J Cuthbert, Thaís Klevorn, Alex Chao, Jessica Mendoza, Mark Arbing, Paul J Sieminski, Kadamba Papavinasasundaram, Sumer Abdul-Hafiz, Sum Chan, Christopher M Sassetti, Sabine Ehrt, Celia W Goulding
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011650 (2023)
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, poses a great threat to human health. With the emergence of drug resistant Mtb strains, new therapeutics are desperately needed. As iron is critical to the growth and survival of
Externí odkaz:
https://doaj.org/article/2a99bc24957f43c6945e528b7dd53b4d
Autor:
Nicholas L. Bartelli, Victor J. Passanisi, Karolina Michalska, Kiho Song, Dinh Q. Nhan, Hongjun Zhou, Bonnie J. Cuthbert, Lucy M. Stols, William H. Eschenfeldt, Nicholas G. Wilson, Jesse S. Basra, Ricardo Cortes, Zainab Noorsher, Youssef Gabraiel, Isaac Poonen-Honig, Elizabeth C. Seacord, Celia W. Goulding, David A. Low, Andrzej Joachimiak, Frederick W. Dahlquist, Christopher S. Hayes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Contact-dependent growth inhibition (CDI) is an important mechanism of bacterial competition. Here, Bartelli et al. show that proteolytic processing of a CDI toxin induces a conformational switch required for translocation into target bacteria.
Externí odkaz:
https://doaj.org/article/86ac2e542326412c8e314121e49b5241
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Bacteria live in complex communities and environments, competing for space and nutrients. Within their niche habitats, bacteria have developed various inter-bacterial mechanisms to compete and communicate. One such mechanism is contact-dependent grow
Externí odkaz:
https://doaj.org/article/9d780feab9584a60b492b6b607bc85ba
Autor:
Nicholas L. Bartelli, Victor J. Passanisi, Karolina Michalska, Kiho Song, Dinh Q. Nhan, Hongjun Zhou, Bonnie J. Cuthbert, Lucy M. Stols, William H. Eschenfeldt, Nicholas G. Wilson, Jesse S. Basra, Ricardo Cortes, Zainab Noorsher, Youssef Gabraiel, Isaac Poonen-Honig, Elizabeth C. Seacord, Celia W. Goulding, David A. Low, Andrzej Joachimiak, Frederick W. Dahlquist, Christopher S. Hayes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/01fc3aaf029c427cba9b0bc69da67bf3
Autor:
Whitney England, Ke Ke, Robert C. Spitale, David L. Mobley, Robert Quechol, Bonnie J. Cuthbert, Celia W. Goulding, Sarah Nainar, Nathan M. Lim, Kanika Sophal
Publikováno v:
Nature methods
Nature methods, vol 17, iss 3
Nature methods, vol 17, iss 3
Tissues and organs are composed of diverse cell types, which poses a major challenge for cell-type-specific profiling of gene expression. Current metabolic labeling methods rely on exogenous pyrimidine analogs that are only incorporated into RNA in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b3aecb9d7632590bb68263e1c324cf
https://doi.org/10.1038/s41592-019-0726-y
https://doi.org/10.1038/s41592-019-0726-y
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128225 (2015)
Francisella tularensis is one of the most infectious bacteria known and is the etiologic agent of tularemia. Francisella virulence arises from a 33 kilobase (Kb) pathogenicity island (FPI) that is regulated by the macrophage locus protein A (MglA) an
Externí odkaz:
https://doaj.org/article/57a03fcf6c7746a1b9b729994e099563
Autor:
Kalistyn H, Burley, Bonnie J, Cuthbert, Piyali, Basu, Jane, Newcombe, Ervin M, Irimpan, Robert, Quechol, Ilona P, Foik, David L, Mobley, Dany J V, Beste, Celia W, Goulding
Publikováno v:
ACS Infect Dis
Tuberculosis (TB) is the most lethal bacterial infectious disease worldwide. It is notoriously difficult to treat, requiring a cocktail of antibiotics administered over many months. The dense, waxy outer membrane of the TB-causing agent, Mycobacteriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67279b371ae5c1d089d0fb749e74a98f
https://pubmed.ncbi.nlm.nih.gov/33356117
https://pubmed.ncbi.nlm.nih.gov/33356117
Autor:
Kalistyn H Burley, Piyali Basu, Robert Quechol, David L. Mobley, Ervin M Irimpan, Ilona P. Foik, Jane Newcombe, Celia W. Goulding, Bonnie J. Cuthbert, Dany J. V. Beste
Tuberculosis (TB) is the most lethal bacterial infectious disease worldwide. It is notoriously difficult to treat, requiring a cocktail of antibiotics administered over many months. The dense, waxy outer membrane of the TB-causing agent, Mycobacteriu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc76e2998cceb099340b8bff316be7b
https://doi.org/10.1101/2020.07.07.192161
https://doi.org/10.1101/2020.07.07.192161
Publikováno v:
RNA biology, vol 15, iss 1
Bovine pancreatic ribonuclease (RNase A) is the founding member of the RNase A superfamily. Members of this superfamily of ribonucleases have high sequence diversity, but possess a similar structural fold, together with a conserved His-Lys-His cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2cd841a4cd500937a91cb42e864405
https://doi.org/10.1080/15476286.2017.1387710
https://doi.org/10.1080/15476286.2017.1387710