Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Bonnie C, Carney"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 230 (2024)
Background: Existing animal models for testing therapeutics in the skin are limited. Mouse and rat models lack similarity to human skin in structure and wound healing mechanism. Pigs are regarded as the best model with regards to similarity to human
Externí odkaz:
https://doaj.org/article/b49c153285a1441889cfc3063087d744
Autor:
Esteban A. Molina, Brandon Hartmann, Mary A. Oliver, Liam D. Kirkpatrick, John W. Keyloun, Lauren T. Moffatt, Jeffrey W. Shupp, Taryn E. Travis, Bonnie C. Carney
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Hypertrophic scar (HTS) formation is a common challenge for patients after burn injury. Dermal microvascular endothelial cells (DMVECs) are an understudied cell type in HTS. An increase in angiogenesis and microvessel density can be observed
Externí odkaz:
https://doaj.org/article/fb18cb3a91fa4afaa34a61a828ce4fde
Autor:
Colton H. Funkhouser, Liam D. Kirkpatrick, Robert D. Smith, Lauren T. Moffatt, Jeffrey W. Shupp, Bonnie C. Carney
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 4, Pp 406-417 (2021)
Abstract Background Wound healing can result in various outcomes, including hypertrophic scar (HTS). Pigs serve as models to study wound healing as their skin shares physiologic similarity with humans. Yorkshire (Yk) and Duroc (Dc) pigs have been use
Externí odkaz:
https://doaj.org/article/5773b4ed7dff495db4277d0bf12e2ce5
Autor:
Bonnie C. Carney, Cynthia M. Simbulan-Rosenthal, Anirudh Gaur, Benjamin J. Browne, Manish Moghe, Elliott Crooke, Lauren T. Moffatt, Jeffrey W. Shupp, Dean S. Rosenthal
Publikováno v:
Regenerative Therapy, Vol 15, Iss , Pp 138-148 (2020)
Wound healing requires well-coordinated events including hemostasis, inflammation, proliferation, and remodeling. Delays in any of these stages leads to chronic wounds, infections, and hypertrophic scarring. Burn wounds are particularly problematic,
Externí odkaz:
https://doaj.org/article/2e8bb191a1984597ba6d173c71498464
Autor:
Nabarun Chakraborty, Seshamalini Srinivasan, Ruoting Yang, Stacy-Ann Miller, Aarti Gautam, Leanne J. Detwiler, Bonnie C. Carney, Abdulnaser Alkhalil, Lauren T. Moffatt, Marti Jett, Jeffrey W. Shupp, Rasha Hammamieh
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1402 (2022)
Staphylococcus aureus, a gram-positive bacterium, causes toxic shock through the production of superantigenic toxins (sAgs) known as Staphylococcal enterotoxins (SE), serotypes A-J (SEA, SEB, etc.), and toxic shock syndrome toxin-1 (TSST-1). The chro
Externí odkaz:
https://doaj.org/article/be9c9a5986d74c008b7f823fa62c2177
Autor:
Bonnie C Carney, Taryn E Travis, Lauren T Moffatt, Laura S Johnson, Melissa M McLawhorn, Cynthia M Simbulan-Rosenthal, Dean S Rosenthal, Jeffrey W Shupp
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248985 (2021)
There are limited treatments for dyschromia in burn hypertrophic scars (HTSs). Initial work in Duroc pig models showed that regions of scar that are light or dark have equal numbers of melanocytes. This study aims to confirm melanocyte presence in re
Externí odkaz:
https://doaj.org/article/20f617bbc51d4e128db83e72673f8c52
Publikováno v:
Journal of Burn Care & Research. 44:535-545
Burn scars, and in particular, hypertrophic scars, are a challenging yet common outcome for survivors of burn injuries. In 2021, the American Burn Association brought together experts in burn care and research to discuss critical topics related to bu
Autor:
Mariana Vigiola Cruz, Jenna N. Luker, Bonnie C. Carney, Kathleen E. Brummel-Ziedins, Maria-Cristina Bravo, Thomas Orfeo, Jason H. Chen, Lauren T. Moffatt, Jeffrey W. Shupp
Publikováno v:
Thrombosis Journal, Vol 15, Iss 1, Pp 1-7 (2017)
Abstract Background A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system. Methods Reference values fo
Externí odkaz:
https://doaj.org/article/dc81dbdcd50f46babbe8864b843bdcfa
Autor:
John W. Keyloun, Tuan D. Le, Thomas Orfeo, Kathleen E. Brummel-Ziedins, Maria C. Bravo, Matthew D. Kaye, Dana E. Bourne, Bonnie C. Carney, Kalev Freeman, Kenneth G. Mann, Anthony E. Pusateri, Jeffrey W. Shupp, Melissa M. McLawhorn, Lauren T. Moffatt, Rachael A. Callcut, Mitchell J. Cohen, Linda R. Petzold, Jeffrey D. Varner, Maria Cristina Bravo, Aarti Gautam, Rasha Hammamieh, Marti Jett
Publikováno v:
Journal of Surgical Research. 274:169-177
Proposed mechanisms of acute traumatic coagulopathy (ATC) include decreased clotting potential due to factor consumption and proteolytic inactivation of factor V (FV) and activated factor V (FVa) by activated protein C (aPC). The role of FV/FVa deple
Autor:
Bonnie C. Carney, Mary A. Oliver, Sanjana Kurup, Monica Collins, John W. Keyloun, Lauren T. Moffatt, Jeffrey W. Shupp, Taryn E. Travis
Publikováno v:
Lasers in Surgery and Medicine.