Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Bonnie A. Avery"'
Autor:
Kathy T. LeSaint, Shan Yin, Abhisheak Sharma, Bonnie A. Avery, Christopher R. McCurdy, Javier C. Waksman
Publikováno v:
The Journal of Emergency Medicine. 63:e28-e30
Kratom (Mitragyna speciosa), an evergreen tree native to Southeast Asia, contains alkaloids that cause both stimulant and opioid-like effects. In the United States, its use continues to grow. Kratom products, however, are unregulated and nonstandardi
Autor:
Yi Wang, Shainnel O Eans, Heather M Stacy, Sreekanth C Narayanapillai, Abhisheak Sharma, Naomi Fujioka, Linda Haddad, Jay McLaughlin, Bonnie A Avery, Chengguo Xing
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197940 (2018)
Kava is regaining its popularity with detailed characterizations warranted. We developed an ultraperformance liquid chromatography high-resolution tandem mass spectrometry (UPLC-MS/MS) method for major kavalactones (kavain, dihydrokavain, methysticin
Externí odkaz:
https://doaj.org/article/3fffdd750ee94a64b3324ae465170f31
Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy
Autor:
Abhisheak Sharma, Christopher R. McCurdy, Carolina Lopera-Londoño, Tamara I. King, Bonnie A. Avery, Shyam H. Kamble, Lance R. McMahon, Francisco León, Aidan J. Hampson, Kanumuri Siva Rama Raju, Erin C. Berthold
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Kratom is widely consumed in the United States for self-treatment of pain and opioid withdrawal symptoms. Mitragynine is the most abundant alkaloid in kratom and is a μ-opioid receptor agonist. 7-Hydroxymitragynine (7-HMG) is a mit
Autor:
Kanumuri Siva Rama Raju, Erin C. Berthold, Elizabeth A. Maxwell, Francisco León, Abhisheak Sharma, Christopher R. McCurdy, Bonnie A. Avery, Tamara I. King, Lance R. McMahon, Shyam H. Kamble
Publikováno v:
Planta Med
Mitragynine is the most abundant psychoactive alkaloid derived from the leaves of Mitragyna speciosa (kratom), a tropical plant indigenous to regions of Southeast Asia. Mitragynine displays a moderate affinity to opioid receptors, and kratom is often
Autor:
Roger Kjelgren, Abhisheak Sharma, Mengzi Zhang, Francisco León, Brian J. Pearson, Bonnie A. Avery, Christopher R. McCurdy
The dose-dependent consumptive effect of kratom and its potential application as an alternative source of medicine to mitigate opioid withdrawal symptoms has brought considerable attention to this plant. Increased interest in the application and use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97eaf038ce62a1cd971d3eda0703794f
https://doi.org/10.1101/2021.10.18.464895
https://doi.org/10.1101/2021.10.18.464895
Autor:
Andrew C. Kruegel, Darshan Singh, Charles A. Veltri, Lance R. McMahon, Jack E. Henningfield, Marc T. Swogger, Edward W. Boyer, Christopher R. McCurdy, Oliver Grundmann, Walter C. Prozialeck, Bonnie A. Avery
Publikováno v:
The International journal on drug policy
Kratom (Mitragyna speciosa) is a tree-like plant indigenous to Southeast Asia. Its leaves, and the teas brewed from them have long been used by people in that region to stave off fatigue and to manage pain and opioid withdrawal. Evidence suggests kra
Autor:
Anna E. Pennington, Francisco León, Jasmine S. Felix, Jenny L. Wilkerson, Luis F. Restrepo, Lance R. McMahon, Bonnie A. Avery, Morgan E. Reeves, Samuel Obeng, Christopher R. McCurdy, Takato Hiranita
Publikováno v:
Psychopharmacology (Berl)
RATIONALE. Mitragyna speciosa (kratom) may hold promise as both an analgesic and treatment for opioid use disorder. Mitragynine, its primary alkaloid constituent, is an opioid receptor ligand. However, the extent to which the in vivo effects of mitra
Autor:
Francisco León, Tamara I. King, Christopher R. McCurdy, Nelson Jeng Yeou Chear, Bonnie A. Avery, Surash Ramanathan, Abhisheak Sharma, Shyam H. Kamble, Erin C. Berthold
Publikováno v:
Drug Test Anal
Kratom (Mitragyna speciosa) is a psychoactive plant popular in the United States for the self-treatment of pain and opioid addiction. For standardization and quality control of raw and commercial kratom products, an ultra-performance liquid chromatog
Autor:
Satya Narayan, Coy D. Heldermon, Renan B. Ferreira, Bonnie A. Avery, Chi Wu Chiang, Brian K. Law, Amanda F. Ghilardi, Elham Yaaghubi, Mary E. Law, Mengxiong Wang, Edgardo Rodriguez, Abhisheak Sharma, Bradley J. Davis, Ronald K. Castellano
Publikováno v:
Oncogene. 38:4264-4282
While HER2 and EGFR are overexpressed in breast cancers and multiple other types of tumors, the use of EGFR and/or HER2 inhibitors have failed to cure many cancer patients, largely because cancers acquire resistance to HER2/EGFR-specific drugs. Cance
Autor:
Siva Rama Raju Kanumuri, Christopher R. McCurdy, Lance R. McMahon, Bonnie A. Avery, Abhisheak Sharma, Julius R Herting, Raluca Popa, Francisco León, Shyam H. Kamble, Tamara I. King, Erin C. Berthold
Publikováno v:
J Nat Prod
Kratom, Mitragyna speciosa Korth., is being widely consumed in the United States for pain management and the reduction of opioid withdrawal symptoms. The central nervous system (CNS) active alkaloids of kratom, including mitragynine, 7-hydroxymitragy