Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Bonnie, Huang"'
Autor:
Helyaneh Ziaei Jam, Yang Li, Ross DeVito, Nima Mousavi, Nichole Ma, Ibra Lujumba, Yagoub Adam, Mikhail Maksimov, Bonnie Huang, Egor Dolzhenko, Yunjiang Qiu, Fredrick Elishama Kakembo, Habi Joseph, Blessing Onyido, Jumoke Adeyemi, Mehrdad Bakhtiari, Jonghun Park, Sara Javadzadeh, Daudi Jjingo, Ezekiel Adebiyi, Vineet Bafna, Melissa Gymrek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tandem repeats (TRs) represent one of the largest sources of genetic variation in humans and are implicated in a range of phenotypes. Here we present a deep characterization of TR variation based on high coverage whole genome sequencing from
Externí odkaz:
https://doaj.org/article/fc3ce6b9d4d04929afdde67a60974243
Autor:
Serap Erdogmus, Axel R. Concepcion, Megumi Yamashita, Ikjot Sidhu, Anthony Y. Tao, Wenyi Li, Pedro P. Rocha, Bonnie Huang, Ralph Garippa, Boram Lee, Amy Lee, Johannes W. Hell, Richard S. Lewis, Murali Prakriya, Stefan Feske
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The function of voltage-gated calcium channels in T cells is not well understood and controversial. Here the authors report that a regulatory beta subunit of voltage-gated calcium channels regulates T cell function despite no evidence that these chan
Externí odkaz:
https://doaj.org/article/5b75fb8dc4614e899839c3361f59e74d
Autor:
Bonnie Huang, James D. Phelan, Silvia Preite, Julio Gomez-Rodriguez, Kristoffer H. Johansen, Hirofumi Shibata, Arthur L. Shaffer, Qin Xu, Brendan Jeffrey, Martha Kirby, Stacie Anderson, Yandan Yang, Selamawit Gossa, Dorian B. McGavern, Louis M. Staudt, Pamela L. Schwartzberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
T follicular helper (Tfh) and T help type 1 (Th1) cells both arise from naïve CD4 T cells, but detailed knowledge of their differentiation remains incomplete. Here the authors pursue an in vivo CRISPR screen to identify genes, focusing on druggable
Externí odkaz:
https://doaj.org/article/f2c40bd54ddf4ca49421a503fe6ad4d6
Autor:
Pooja Biswas, Adda L Villanueva, Angel Soto-Hermida, Jacque L Duncan, Hiroko Matsui, Shyamanga Borooah, Berzhan Kurmanov, Gabriele Richard, Shahid Y Khan, Kari Branham, Bonnie Huang, John Suk, Benjamin Bakall, Jeffrey L Goldberg, Luis Gabriel, Naheed W Khan, Pongali B Raghavendra, Jason Zhou, Sindhu Devalaraja, Andrew Huynh, Akhila Alapati, Qais Zawaydeh, Richard G Weleber, John R Heckenlively, J Fielding Hejtmancik, Sheikh Riazuddin, Paul A Sieving, S Amer Riazuddin, Kelly A Frazer, Radha Ayyagari
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009848 (2021)
Patients with inherited retinal dystrophies (IRDs) were recruited from two understudied populations: Mexico and Pakistan as well as a third well-studied population of European Americans to define the genetic architecture of IRD by performing whole-ge
Externí odkaz:
https://doaj.org/article/100510e296874924a61b4222d50d1e2c
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
T follicular helper (Tfh) cells are a specialized population of CD4+ T cells that provide help to B cells for the formation and maintenance germinal centers, and the production of high affinity class-switched antibodies, long-lived plasma cells, and
Externí odkaz:
https://doaj.org/article/cc9c5be036654d7aa3cceebefd4503c1
Publikováno v:
Journal of Safety Research. 79:368-375
Introduction: Older drivers are believed to be prone to crashes due to age-related deterioration of their driving abilities. Currently, little is known about the characteristics of repeat crashers and the factors that predict subsequent crashes among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577f713dc84c067dcec506e5fe6c3a2e
https://doi.org/10.1016/j.jsr.2021.10.003
https://doi.org/10.1016/j.jsr.2021.10.003
Autor:
Tuoqi Wu, Hyun Mu Shin, E. Ashley Moseman, Yun Ji, Bonnie Huang, Christelle Harly, Jyoti M. Sen, Leslie J. Berg, Luca Gattinoni, Dorian B. McGavern, Pamela L. Schwartzberg
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 2099-2110 (2015)
T follicular helper (TFH) and T helper 1 (Th1) cells generated after viral infections are critical for the control of infection and the development of immunological memory. However, the mechanisms that govern the differentiation and maintenance of th
Externí odkaz:
https://doaj.org/article/3c3cfee35705436eae052daf1f1a1415
Autor:
Kristoffer H. Johansen, Dominic P. Golec, Bonnie Huang, Chung Park, Julie H. Thomsen, Silvia Preite, Jennifer L. Cannons, Fabien Garçon, Edward C. Schrom, Christina J. F. Courrèges, Tibor Z. Veres, James Harrison, Meritxell Nus, James D. Phelan, Wolfgang Bergmeier, John H. Kehrl, Klaus Okkenhaug, Pamela L. Schwartzberg
Publikováno v:
Sci Signal
The integrin lymphocyte function–associated antigen 1 (LFA-1) helps to coordinate the migration, adhesion, and activation of T cells through interactions with intercellular adhesion molecule 1 (ICAM-1) and ICAM-2. LFA-1 is activated during the enga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fb60de16563b9cf6b443148e4cfc18
https://doi.org/10.1126/scisignal.abl9169
https://doi.org/10.1126/scisignal.abl9169
Publikováno v:
Obstetric Medicine. 15:151-159
We present the case of a woman with a history of biliopancreatic diversion and duodenal switch procedure who developed severe malnourishment requiring total parenteral nutrition during three pregnancies. The widespread use of bariatric surgery, parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778533c4ea94d68a7965fe57e96f6ef3
https://doi.org/10.1177/1753495x211013624
https://doi.org/10.1177/1753495x211013624
Autor:
Bonnie Huang, Arun Durvasula, Nima Mousavi, Helyaneh Ziaei-Jam, Mikhail Maksimov, Kirk E. Lohmueller, Melissa Gymrek
Short tandem repeats (STRs) comprising repeated sequences of 1-6 bp are one of the largest sources of genetic variation in humans. STRs are known to contribute to a variety of disorders, including Mendelian diseases, complex traits, and cancer. Based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9edc244a96c2b597ea43eca6e44b997c
https://doi.org/10.1101/2022.05.12.491726
https://doi.org/10.1101/2022.05.12.491726
