An Optimized Model of Hypertrophic Preconditioning Confers Cardioprotection in the Mouse.

Autor: Cai X; Department of Cardiology, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an Shaanxi, China., Tian Y; Department of Cardiology, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an Shaanxi, China., Wu Y; Department of Cardiology, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an Shaanxi, China., Bonner MY; Division of Medical Inflammation Research, Department of Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Zhuo X; Department of Cardiology, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an Shaanxi, China. Electronic address: imxiaozhen@xjtu.edu.cn., Yuan Z; Department of Cardiology, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an Shaanxi, China. Electronic address: zuyiyuan@mail.xjtu.edu.cn.

Publikováno v: The Journal of surgical research [J Surg Res] 2021 Aug; Vol. 264, pp. 544-552. Date of Electronic Publication: 2021 Apr 14.

Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation.

Autor: Norin U; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden. Ulrika_norin@hotmail.com., Rintisch C; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.; Medical Inflammation Research, Lund University, Lund, Sweden.; Cardiovascular and Metabolic Sciences, Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany., Meng L; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.; The Second affiliated hospital to Xi'an Jiaotong University and the Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 710061, Xi'an, Shaanxi, China., Forster F; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Ekman D; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.; Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Stockholm University, Stockholm, Sweden., Tuncel J; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Klocke K; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Bäcklund J; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Yang M; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Bonner MY; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Lahore GF; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., James J; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Shchetynsky K; Rheumatology Unit, Department of Medicine, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden., Bergquist M; Department of Rheumatology and Inflammation Research, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden., Gjertsson I; Department of Rheumatology and Inflammation Research, Institute for Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Hubner N; Cardiovascular and Metabolic Sciences, Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany.; Charité-Universitätsmedizin Berlin, Berlin, Germany., Bäckdahl L; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden., Holmdahl R; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden. rikard.holmdahl@ki.se.; The Second affiliated hospital to Xi'an Jiaotong University and the Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 710061, Xi'an, Shaanxi, China. rikard.holmdahl@ki.se.

Publikováno v: Nature communications [Nat Commun] 2021 Jan 27; Vol. 12 (1), pp. 610. Date of Electronic Publication: 2021 Jan 27.

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo .

Autor: Musi E; Department of Medicine, Columbia University Medical Center, New York, New York, USA., Schwartz GK; Department of Medicine, Columbia University Medical Center, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University College of Medicine, New York, New York, USA., Yoo JH; Department of Medicine, Program in Molecular Medicine, University of Utah, Salt Lake City, Utah, USA., Odelberg SJ; Department of Medicine, Program in Molecular Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Neurobiology and Anatomy, University of Utah, Salt Lake City, Utah, USA.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA., Li DY; Department of Medicine, Program in Molecular Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Oncological Sciences, University of Utah, Salt Lake City, Utah, USA., Bonner MY; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA., Selvakumar P; Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Rao S; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA., Gilbert LC; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA.; Veterans Affairs Medical Center, Decatur, Georgia, USA., Elsey J; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA., Arbiser JL; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA.; Veterans Affairs Medical Center, Decatur, Georgia, USA.

Publikováno v: Oncotarget [Oncotarget] 2019 Jul 09; Vol. 10 (43), pp. 4424-4436. Date of Electronic Publication: 2019 Jul 09 (Print Publication: 2019).

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.

Autor: Sengupta S; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Nagalingam A; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Muniraj N; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Bonner MY; Department of Dermatology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA., Mistriotis P; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore MD, USA., Afthinos A; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore MD, USA., Kuppusamy P; Department of Medicine, University of Maryland School of Medicine, Baltimore MD, USA., Lanoue D; Department of Biochemistry and Molecular Biology, Dalhousie University, Nova Scotia Canada., Cho S; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Korangath P; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Shriver M; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Begum A; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Merino VF; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Huang CY; Division of Biostatistics and Bioinformatics, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA., Arbiser JL; Department of Dermatology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA.; Atlanta Veterans Administration Medical Center, Atlanta, GA, USA., Matsui W; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Győrffy B; MTA TTK Momentum Cancer Biomarker Research Group, Budapest, Hungary.; Semmelweis University 2nd Department of Pediatrics, Budapest, Hungary., Konstantopoulos K; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore MD, USA., Sukumar S; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA., Marignani PA; Department of Biochemistry and Molecular Biology, Dalhousie University, Nova Scotia Canada., Saxena NK; Department of Medicine, University of Maryland School of Medicine, Baltimore MD, USA., Sharma D; Department of Oncology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore MD, USA.

Publikováno v: Oncogene [Oncogene] 2017 Oct 12; Vol. 36 (41), pp. 5709-5721. Date of Electronic Publication: 2017 Jun 05.

Activation of Protein Kinase C ε in Merkel Cell Polyomavirus-Induced Merkel Cell Carcinoma.

Autor: Costa A; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.; Atlanta Veterans Administration Medical Center, Atlanta, Georgia., Mackelfresh J; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.; Department of Pathology, Emory University School of Medicine, Atlanta, Georgia., Gilbert L; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.; Atlanta Veterans Administration Medical Center, Atlanta, Georgia., Bonner MY; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.; Atlanta Veterans Administration Medical Center, Atlanta, Georgia., Arbiser JL; Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.; Atlanta Veterans Administration Medical Center, Atlanta, Georgia.

Publikováno v: JAMA dermatology [JAMA Dermatol] 2017 Sep 01; Vol. 153 (9), pp. 931-932.