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Akademický článek

Metal-Catalyzed Hydrogen Atom Transfer (MHAT) Hydroalkylation with Electron-Deficient Alkynes.

Autor: Rodríguez LG; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Barcelona 08028, Spain., Bonjoch J; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Barcelona 08028, Spain., Bradshaw B; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Barcelona 08028, Spain.

Publikováno v: Organic letters [Org Lett] 2024 Dec 13; Vol. 26 (49), pp. 10553-10558. Date of Electronic Publication: 2024 Nov 28.

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Akademický článek

Synthesis of the ABC Core of Daphniphyllum Alkaloids with a [5-6-7] Azatricyclic Scaffold via Ring Expansion of Azabicyclic and Azatricyclic Building Blocks.

Autor: Marquès C; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain., González-Lizana D; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain., Diaba F; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain., Bonjoch J; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2024 Jul 19; Vol. 89 (14), pp. 10212-10222. Date of Electronic Publication: 2024 Jul 01.

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Akademický článek

Isocyanides as Acceptor Groups in MHAT Reactions with Unactivated Alkenes.

Autor: Puig J; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain., Bonjoch J; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain., Bradshaw B; Laboratori de Química Orgànica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain.

Publikováno v: Organic letters [Org Lett] 2023 Sep 08; Vol. 25 (35), pp. 6539-6543. Date of Electronic Publication: 2023 Aug 30.

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Akademický článek

Targeting lymphoid-derived IL-17 signaling to delay skin aging.

Autor: Solá P; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain., Mereu E; Josep Carreras Leukemia Research Institute, Badalona, Spain., Bonjoch J; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain., Casado-Peláez M; Josep Carreras Leukemia Research Institute, Badalona, Spain., Prats N; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain., Aguilera M; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain., Reina O; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain., Blanco E; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain., Esteller M; Josep Carreras Leukemia Research Institute, Badalona, Spain.; ICREA, Catalan Institution for Research and Advanced Studies, Barcelona, Spain., Di Croce L; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.; ICREA, Catalan Institution for Research and Advanced Studies, Barcelona, Spain., Heyn H; Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain. holger.heyn@cnag.crg.eu., Solanas G; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain. guiomar.solanas@irbbarcelona.org., Benitah SA; Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, Spain. salvador.aznar-benitah@irbbarcelona.org.; ICREA, Catalan Institution for Research and Advanced Studies, Barcelona, Spain. salvador.aznar-benitah@irbbarcelona.org.

Publikováno v: Nature aging [Nat Aging] 2023 Jun; Vol. 3 (6), pp. 688-704. Date of Electronic Publication: 2023 Jun 08.

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Akademický článek

Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice.

Autor: Kam CY; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Singh ID; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Gonzalez DG; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Matte-Martone C; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Solá P; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Solanas G; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Bonjoch J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., Marsh E; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA., Hirschi KK; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. Electronic address: kkh4yy@virginia.edu., Greco V; Department of Genetics, Yale School of Medicine, New Haven, CT 06510, USA; Departments of Cell Biology and Dermatology, Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: valentina.greco@yale.edu.

Publikováno v: Cell [Cell] 2023 May 25; Vol. 186 (11), pp. 2345-2360.e16. Date of Electronic Publication: 2023 May 10.

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Akademický článek

Four-Step Synthesis of (-)-4-epi-Presilphiperfolan-8α-ol by Intramolecular Iron Hydride Atom Transfer-Mediated Ketone-Alkene Coupling and Studies to Access trans-Hydrindanols with a Botryane Scaffold.

Autor: Saladrigas M; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain., Gómez-Bengoa E; Departamento de Química Orgánica I, Universidad del País Vasco, Manuel Lardizábal 3, 20018, San Sebastián, Spain., Bonjoch J; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain., Bradshaw B; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 Mar 13; Vol. 29 (15), pp. e202203286. Date of Electronic Publication: 2023 Feb 08.

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Akademický článek

Base-Mediated Nitrophenyl Reductive Cyclization for the Synthesis of Hexahydro-2,6-methano-1-benzazocines.

Autor: Rodríguez LG; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Avenida Joan XXIII 27-31, 08028 Barcelona, Spain., Delgado A; Department of Biochemistry and Physiology, Faculty of Pharmacy & IN2UB, University of Barcelona, Avenida Joan XXIII 27-31, 08028 Barcelona, Spain., Ciudad CJ; Department of Biochemistry and Physiology, Faculty of Pharmacy & IN2UB, University of Barcelona, Avenida Joan XXIII 27-31, 08028 Barcelona, Spain., Noé V; Department of Biochemistry and Physiology, Faculty of Pharmacy & IN2UB, University of Barcelona, Avenida Joan XXIII 27-31, 08028 Barcelona, Spain., Bonjoch J; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Avenida Joan XXIII 27-31, 08028 Barcelona, Spain., Bradshaw B; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Avenida Joan XXIII 27-31, 08028 Barcelona, Spain.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2022 Nov 18; Vol. 87 (22), pp. 15693-15702. Date of Electronic Publication: 2022 Nov 03.

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Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

Publikováno v: CELLULAR AND MOLECULAR LIFE SCIENCES
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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Cholesterol accumulation in late endosomes is a prevailing phenotype of Niemann-Pick type C1 (NPC1) mutant cells. Likewise, annexin A6 (AnxA6) overexpression induces a phenotype reminiscent of NPC1 mutant cells. Here, we demonstrate that this cellula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::9c5b3239cbad3647e1c3b8b7610cb155
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10191

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Akademický článek

Synthesis of the ABC Ring of Calyciphylline A-Type Alkaloids by a Stereocontrolled Aldol Cyclization: Formal Synthesis of (±)-Himalensine A.

Autor: Marquès C; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028-Barcelona, Spain., Diaba F; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028-Barcelona, Spain., Gómez-Bengoa E; Departamento de Química Orgánica I, Universidad del País Vasco, Manuel Lardizábal 3, 20018 San Sebastián, Spain., Bonjoch J; Laboratori de Química Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII 27-31, 08028-Barcelona, Spain.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2022 Aug 05; Vol. 87 (15), pp. 10516-10522. Date of Electronic Publication: 2022 Jul 21.

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