Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Bonita J. Brewer"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/7b5fd2de7d7548078a310681a438610e
Autor:
Rebecca Martin, Claudia Y. Espinoza, Christopher R. L. Large, Joshua Rosswork, Cole Van Bruinisse, Aaron W. Miller, Joseph C. Sanchez, Madison Miller, Samantha Paskvan, Gina M. Alvino, Maitreya J. Dunham, M. K. Raghuraman, Bonita J. Brewer
Publikováno v:
PLoS Genetics, Vol 20, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/442bff6d3b6e4116bbcefd688a9e16f1
Autor:
Elizabeth X. Kwan, Gina M. Alvino, Kelsey L. Lynch, Paula F. Levan, Haley M. Amemiya, Xiaobin S. Wang, Sarah A. Johnson, Joseph C. Sanchez, Madison A. Miller, Mackenzie Croy, Seung-been Lee, Maria Naushab, Antonio Bedalov, Josh T. Cuperus, Bonita J. Brewer, Christine Queitsch, M.K. Raghuraman
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112161- (2023)
Summary: Timely completion of genome replication is a prerequisite for mitosis, genome integrity, and cell survival. A challenge to this timely completion comes from the need to replicate the hundreds of untranscribed copies of rDNA that organisms ma
Externí odkaz:
https://doaj.org/article/52aee668d64145149ab27041aab50554
Autor:
Elizabeth A. Morton, Ashley N. Hall, Elizabeth Kwan, Calvin Mok, Konstantin Queitsch, Vivek Nandakumar, John Stamatoyannopoulos, Bonita J. Brewer, Robert Waterston, Christine Queitsch
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 1, Pp 417-430 (2020)
Individuals within a species can exhibit vast variation in copy number of repetitive DNA elements. This variation may contribute to complex traits such as lifespan and disease, yet it is only infrequently considered in genotype-phenotype associations
Externí odkaz:
https://doaj.org/article/2aa0e1c9e4854b5a8b31e14929ff203f
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 9, Pp 2829-2838 (2016)
The Saccharomyces cerevisiae ribosomal DNA (rDNA) locus is known to exhibit greater instability relative to the rest of the genome. However, wild-type cells preferentially maintain a stable number of rDNA copies, suggesting underlying genetic control
Externí odkaz:
https://doaj.org/article/cb66e24a57e74a2d88139da6632bfdb5
Autor:
Remington E Hoerr, Alex Eng, Celia Payen, Sara C Di Rienzi, M K Raghuraman, Maitreya J Dunham, Bonita J Brewer, Katherine L Friedman
Publikováno v:
GENETICS. 224
Evolution is driven by the accumulation of competing mutations that influence survival. A broad form of genetic variation is the amplification or deletion of DNA (≥50 bp) referred to as copy number variation (CNV). In humans, CNV may be inconsequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f18188ce73e54d05eb860a33ba2ae1
https://doi.org/10.1093/genetics/iyad010
https://doi.org/10.1093/genetics/iyad010
Autor:
Joseph C Sanchez, Elizabeth X Kwan, Thomas J Pohl, Haley M Amemiya, M K Raghuraman, Bonita J Brewer
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007041 (2017)
A form of dwarfism known as Meier-Gorlin syndrome (MGS) is caused by recessive mutations in one of six different genes (ORC1, ORC4, ORC6, CDC6, CDT1, and MCM5). These genes encode components of the pre-replication complex, which assembles at origins
Externí odkaz:
https://doaj.org/article/c428286c82bd4029ae1c65b1892d6f21
Autor:
Remington E. Hoerr, Alex Eng, Celia Payen, Sara C. Di Rienzi, M. K. Raghuraman, Maitreya J. Dunham, Bonita J. Brewer, Katherine L. Friedman
Evolution is driven by the accumulation of competing mutations that influence survival. A broad form of genetic variation is the amplification or deletion of DNA (≥50 bp) referred to as copy number variation. In humans, copy number variation may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f01d7894fa01806a081c5bc2420639c
https://doi.org/10.1101/2022.06.12.495855
https://doi.org/10.1101/2022.06.12.495855
Autor:
Calvin A. Mok, Christine Queitsch, Konstantin Queitsch, Vivek Nandakumar, Ashley N. Hall, Elizabeth A. Morton, Elizabeth X. Kwan, Bonita J. Brewer, John A. Stamatoyannopoulos, Robert H. Waterston
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 1, Pp 417-430 (2020)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Individuals within a species can exhibit vast variation in copy number of repetitive DNA elements. This variation may contribute to complex traits such as lifespan and disease, yet it is only infrequently considered in genotype-phenotype associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e520289977feb29922426e749a4635c4
http://g3journal.org/lookup/doi/10.1534/g3.119.400771
http://g3journal.org/lookup/doi/10.1534/g3.119.400771
Autor:
Bonita J Brewer, Celia Payen, Sara C Di Rienzi, Megan M Higgins, Giang Ong, Maitreya J Dunham, M K Raghuraman
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005699 (2015)
DNA replication errors are a major driver of evolution--from single nucleotide polymorphisms to large-scale copy number variations (CNVs). Here we test a specific replication-based model to explain the generation of interstitial, inverted triplicatio
Externí odkaz:
https://doaj.org/article/c31b5a7f3f8b49608fa44c43471b7a27