Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bonita J. Biegalke"'
Autor:
Rico Rana, Bonita J. Biegalke
Publikováno v:
Viruses, Vol 6, Iss 2, Pp 476-488 (2014)
UL34 is one of the ~50 genes of human cytomegalovirus (HCMV) required for replication in cell culture in human fibroblasts. UL34 encodes highly related early (UL34a) and late (UL34b) proteins that are virtually identical, with the early protein conta
Externí odkaz:
https://doaj.org/article/aa795c80448947a19a08947d3cc33c74
Publikováno v:
Virology. 518:414-422
The human cytomegalovirus (HCMV) UL34 gene encodes sequence-specific DNA-binding proteins (pUL34) which are required for viral replication. Interactions of pUL34 with DNA binding sites represses transcription of two viral immune evasion genes, US3 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049b674687661f4241323b2657751d5f
https://doi.org/10.1016/j.virol.2018.03.017
https://doi.org/10.1016/j.virol.2018.03.017
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 41:503-506
Human cytomegalovirus (HCMV) is a common infection, opportunistically causing disease in people with immune system deficits. HCMV expresses several proteins that contribute to avoidance of the host immune response. The US3 gene is one of the first im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e818f59bece8872ed232be576346201
https://doi.org/10.1016/j.biocel.2008.10.012
https://doi.org/10.1016/j.biocel.2008.10.012
Autor:
Jinwook Shin, Sung-Wook Lee, Seongman Kang, Kwangseog Ahn, Boyoun Park, Young-Kyun Kim, Bonita J. Biegalke
Publikováno v:
Journal of Virology. 80:5397-5404
Human cytomegalovirus encodes four unique short (US) region proteins, each of which is independently sufficient for causing the down-regulation of major histocompatibility complex (MHC) class I molecules on the cell surface. This down-regulation enab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a85a4ee74849bf9926393b49fb9b99
https://doi.org/10.1128/jvi.02397-05
https://doi.org/10.1128/jvi.02397-05
Publikováno v:
Virology. 301(1):32-42
Similar to other herpesviruses, human cytomegalovirus remains in the infected host following resolution of the primary infection. The ability to persist in the host after primary infection is believed to be strongly influenced by the ability of HCMV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056d2cb286e76c1bec07fc861f7cbf67
Autor:
Bonita J. Biegalke, Yingguang Liu
Publikováno v:
Journal of Virology. 76:2460-2468
The human cytomegalovirus (HCMV) virion is a complex structure that contains at least 30 proteins, many of which have been identified. We determined that the HCMV UL35 gene encodes two proteins, including a previously unidentified virion protein. A 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb458deac258a52654c0c01e248905c7
https://doi.org/10.1128/jvi.76.5.2460-2468.2002
https://doi.org/10.1128/jvi.76.5.2460-2468.2002
Autor:
Yingguang Liu, Bonita J. Biegalke
Publikováno v:
Virus Genes. 23:247-256
Human cytomegalovirus (HCMV) is the most common congenital infection, and is associated with a high rate of morbidity and mortality in the newborn infant. Guinea pig cytomegalovirus (GPCMV) is transmitted through the placenta with resulting fetal inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2b7122764958f24e827a7f88767d2e7
https://doi.org/10.1023/a:1012536804190
https://doi.org/10.1023/a:1012536804190
Autor:
Ziqi Liu, Bonita J. Biegalke
The human cytomegalovirus UL34 gene encodes a sequence-specific DNA binding protein that downregulates expression of the viral immune evasion gene US3. Analysis of the viral genome identified 14 potential UL34 binding sites. Using mobility shift expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038a8fef4f1e27624f001c1820a0c52d
https://europepmc.org/articles/PMC3592156/
https://europepmc.org/articles/PMC3592156/
Autor:
Bonita J. Biegalke
Publikováno v:
Journal of Virology. 69:5362-5367
Regulation of immediate-early gene expression in human cytomegalovirus is subject to complex controls. The major immediate-early (mIE) gene is regulated by both positive and negative regulatory signals, including autoregulation mediated by a cis-repr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ea42fb9a57c7872c8b4edd90e9511f
https://doi.org/10.1128/jvi.69.9.5362-5367.1995
https://doi.org/10.1128/jvi.69.9.5362-5367.1995
Publikováno v:
Journal of virology. 78(17)
UL34 encodes the transcriptional repressor of the human cytomegalovirus immune evasion gene, US3, and is essential for viral replication in tissue culture. Two different monocistronic transcripts originate from UL34 at early and late times postinfect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67988530596358ba1786a1f01cbc1b62
https://pubmed.ncbi.nlm.nih.gov/15308752
https://pubmed.ncbi.nlm.nih.gov/15308752