Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bonita G. Taffe"'
Autor:
Thomas W. Kensler, Bonita G. Taffe
Publikováno v:
Genes and Signal Transduction in Multistage Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cada556d4a08858dfec7889dc523c8a5
https://doi.org/10.1201/9781003066101-22
https://doi.org/10.1201/9781003066101-22
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 15:114-119
Lipid and DNA oxidation catalyzed by iron(II) were compared in HEPES and phosphate buffers. Lipid peroxidation was examined in a sensitive liposome system constructed with a fluorescent probe that allowed us to examine the effects of both low and hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46436b0ce827b816c09a11f5c69a32c
https://doi.org/10.1002/jbt.7
https://doi.org/10.1002/jbt.7
Autor:
Deborah L. Croteau, Jacques Laval, Vilhelm A. Bohr, R. Michael Anson, Bonita G. Taffe, Florence Larminat
Publikováno v:
Mutation Research/DNA Repair. 364:183-192
This study examines the capacity of a mammalian cell to repair, at the gene level, DNA base lesions generated by photoactivation of acridine orange. Chinese hamster ovary fibroblasts were exposed to acridine orange and visible light, and gene-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232fba1c1885264b422cb675b20d9c13
https://doi.org/10.1016/s0921-8777(96)00031-6
https://doi.org/10.1016/s0921-8777(96)00031-6
Publikováno v:
Mutation Research/Genetic Toxicology. 259:387-397
Fecapentaenes are a class of conjugated ether lipids which have been identified as the major component of human fecal mutagenicity in the Ames Salmonella mutagenesis assay. Human epidemiologic data have indicated that most healthy North American popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4f9d80606be251c14a69b18ac73769
https://doi.org/10.1016/0165-1218(91)90129-a
https://doi.org/10.1016/0165-1218(91)90129-a
Publikováno v:
Environmental Health Perspectives
Ionizing radiation produces a variety of damaging insults to nucleic acids, including the promutagenic lesion 8-hydroxydeoxyguanosine. In the present study, the 8-hydroxydeoxyguanosine content of peripheral blood leukocyte DNA isolated from individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48040ffb6eee8d9a256391eab1f3321
https://doi.org/10.1289/ehp.9399261
https://doi.org/10.1289/ehp.9399261
Autor:
Bonita G. Taffe, Jan H.J. Hoeijmakers, Geert Weeda, V. Moncollin, L. Schaeffer, Jean-Marc Egly, Kathleen Forrester, Michele K. Evans, Chris Harris, Heidi Yeh, Vilhelm A. Bohr, Richard Roy, Errol C. Friedberg, Xin Wei Wang, Zhigang Wang
Publikováno v:
Nature genetics. 10(2)
p53 has pleiotropic functions including control of genomic plasticity and integrity. Here we report that p53 can bind to several transcription factor IIH−associated factors, including transcription−repair factors, XPD (Rad3) and XPB, as well as C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9072808442ee64137c3e506fa14e6a96
https://pubmed.ncbi.nlm.nih.gov/7663514
https://pubmed.ncbi.nlm.nih.gov/7663514
Autor:
Bonita G. Taffe, K. Gregory Moore, Lorraine E. Twerdok, Thomas W. Kensler, Michael A. Trush, Patricia A. Egner
Publikováno v:
Toxicology and Applied Pharmacology. 90:337-346
Oxidants, such as those generated by activated polymorphonuclear leukocytes (PMNs) during inflammation, have been implicated in the metabolic activation of procarcinogens to their ultimate carcinogenic form. In this study we examined the effect of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d0fff56bff0811675f65c21b07e19a
https://doi.org/10.1016/0041-008x(87)90341-3
https://doi.org/10.1016/0041-008x(87)90341-3
Autor:
Bonita G. Taffe, Thomas W. Kensler
Publikováno v:
Advances in Free Radical Biology & Medicine. 2:347-387
The induction of cancer by chemicals proceeds through a series of stages as a normal cell transforms into a malignant neoplasm. Free radicals, particularly those derived from molecular oxygen, may participate throughout these transitions. In this art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63f9d2a7351a45c3c90879680b8b1f67
https://doi.org/10.1016/s8755-9668(86)80019-9
https://doi.org/10.1016/s8755-9668(86)80019-9
Publikováno v:
Biology of Copper Complexes ISBN: 9781461289371
The induction of cancer by chemicals involves multiple stages as the target cell progresses from its normal phenotype into a malignant neoplasm. These stages can be operationally defined as initiation, promotion, and progression. Although first descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f35f86a514f2d810d2dcd574690f29d
https://doi.org/10.1007/978-1-4612-4584-1_31
https://doi.org/10.1007/978-1-4612-4584-1_31
Publikováno v:
Carcinogenesis. 10(7)
BHTOOH (2,6-di-tert-butyl-4-hydroperoxyl-4-methyl-2,5-cyclohexadienone), a metabolite of the food antioxidant BHT (2,6-di-tert-butyl-4-methylphenol), has previously been shown to function as a tumor promoter in mouse skin. The metabolism of BHTOOH wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a31ecba06d4b6731d46c21f8c7fea4
https://pubmed.ncbi.nlm.nih.gov/2472232
https://pubmed.ncbi.nlm.nih.gov/2472232