Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Bonita Coutermarsh"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127742 (2015)
P. aeruginosa is an opportunistic pathogen that chronically infects the lungs of 85% of adult patients with Cystic Fibrosis (CF). Previously, we demonstrated that P. aeruginosa reduced wt-CFTR Cl secretion by airway epithelial cells. Recently, a new
Externí odkaz:
https://doaj.org/article/1157a6f42c50499aa48b52ab0e9c7266
Autor:
Emily G Notch, Britton C Goodale, Roxanna Barnaby, Bonita Coutermarsh, Brent Berwin, Vivien F Taylor, Brian P Jackson, Bruce A Stanton
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142392 (2015)
Arsenic is the number one contaminant of concern with regard to human health according to the World Health Organization. Epidemiological studies on Asian and South American populations have linked arsenic exposure with an increased incidence of lung
Externí odkaz:
https://doaj.org/article/8ed1600c299b42958253dc4f024f16e8
Autor:
Bruce A. Stanton, Vahid Farrokhi, Tim Jensen, Bonita Coutermarsh, Elizabeth Joseloff, John R. Riordan, Xudong Yao, Pamela A. Diego-Limpin, Diana R. Wetmore, Adam J. McShane, Bekim Bajrami, Alex A. Ramos
Publikováno v:
Journal of Proteome Research
Deficient chloride transport through cystic fibrosis (CF) transmembrane conductance regulator (CFTR) causes lethal complications in CF patients. CF is the most common autosomal recessive genetic disease, which is caused by mutations in the CFTR gene;
Publikováno v:
Journal of Biological Chemistry. 287:17130-17139
Arsenic exposure significantly increases respiratory bacterial infections and reduces the ability of the innate immune system to eliminate bacterial infections. Recently, we observed in the gill of killifish, an environmental model organism, that ars
Autor:
Britton C. Goodale, Brent Berwin, Brian P. Jackson, Bruce A. Stanton, Emily G. Notch, Roxanna Barnaby, Vivien F. Taylor, Bonita Coutermarsh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 11, p e0142392 (2015)
PLoS ONE, Vol 10, Iss 11, p e0142392 (2015)
Arsenic is the number one contaminant of concern with regard to human health according to the World Health Organization. Epidemiological studies on Asian and South American populations have linked arsenic exposure with an increased incidence of lung
Autor:
Sara Stanton, John VanderHeide, Taylor LaCasse, Bruce A. Stanton, Bonita Coutermarsh, Jennifer M. Bomberger, Roxanna Barnaby, Joseph R. Shaw
Publikováno v:
Aquatic Toxicology. 98:157-164
Seawater acclimation in killifish, Fundulus heteroclitus , is mediated in part by a rapid (1 h) translocation of CFTR Cl − channels from an intracellular pool to the plasma membrane in gill and increased CFTR-mediated Cl − secretion. This effect
Publikováno v:
Cellular Physiology and Biochemistry. 23:199-204
Background: P. aeruginosa chronically colonizes the lung in CF patients and elicits a proinflammatory response. Excessive secretion of IL-6 and IL-8 by CF airway cells in response to P. aeruginosa infection in the CF airway is though to contribute to
Autor:
Bonita Coutermarsh, Roxanna Barnaby, Agnieszka Swiatecka-Urban, George M. Langford, Laleh Talebian, Eiko Kanno, Sophie Moreau-Marquis, Mitsunori Fukuda, Katherine H. Karlson, Bruce A. Stanton, Richard E. Cheney, Karyn Hansen
Publikováno v:
Journal of Biological Chemistry. 282:23725-23736
Cystic fibrosis transmembrane conductance regulator (CFTR)-mediated Cl(-) secretion across fluid-transporting epithelia is regulated, in part, by modulating the number of CFTR Cl(-) channels in the plasma membrane by adjusting CFTR endocytosis and re
Autor:
Jie Cheng, Bonita Coutermarsh, Dean R. Madden, Katherine H. Karlson, Dale F. Mierke, Laleh Talebian, Michael Wolde, Bruce A. Stanton, William B. Guggino, Andrea Piserchio, Abigail M. Fellows, Aleksandr Kivenson
Publikováno v:
Journal of Biological Chemistry. 282:8099-8109
PDZ domains are ubiquitous peptide-binding modules that mediate protein-protein interactions in a wide variety of intracellular trafficking and localization processes. These include the pathways that regulate the membrane trafficking and endocytic re
Autor:
Bruce A. Stanton, Bonita Coutermarsh, Joshua W. Hamilton, Lydia Durant, Caitlin R. Stanton, Katherine H. Karlson, J. Denry Sato, Roxanna Barnaby, Emily Hand, Kristen Gabor, Joseph R. Shaw, Alexander Lankowski, Renee Thibodeau
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 292:R1052-R1060
Killifish are euryhaline teleosts that adapt to rapid changes in the salinity of the seawater. It is generally accepted that acclimation to seawater is mediated by cortisol activation of the glucocorticoid receptor (GR), which stimulates CFTR mRNA ex