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Individual HLA-A, -B, -C, and -DRB1 Genotypes Are No Major Factors Which Determine COVID-19 Severity
Autor:
Schetelig, Johannes, Heidenreich, Falk, Baldauf, Henning, Trost, Sarah, Falk, Bose, Hoßbach, Christian, Real, Ruben, Roers, Axel, Lindemann, Dirk, Dalpke, Alexander, Kolditz, Martin, de With, Katja, Bornhäuser, Martin, Bonifacio, Ezio E., Rücker-Braun, Elke, Lange, Vinzenz, Markert, Jan, Barth, Ralf, Hofmann, Jan A., Sauter, Jürgen, Bernas, Stefanie N., Schmidt, Alexander H.
Publikováno v:
Frontiers in Immunology
HLA molecules are key restrictive elements to present intracellular antigens at the crossroads of an effective T-cell response against SARS-CoV-2. To determine the impact of the HLA genotype on the severity of SARS-CoV-2 courses, we investigated data