Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Boniek G, Vaz"'
Autor:
Michael N. Yakubu, Victor I. Mwangi, Rebeca L. A. Netto, Maria G. C. Alecrim, Jessica R. S. Alves, Anne C. G. Almeida, Gabriel F. Santos, Gesiane S. Lima, Lucas S. Machado, Hector H. F. Koolen, Tiago P. Guimarães, Andrea R. Chaves, Boniek G. Vaz, Wuelton M. Monteiro, Fabio T. M. Costa, Marcus V. G. Lacerda, Luiz G. Gardinassi, Gisely C. de Melo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Malaria is the leading parasitic disease worldwide, with P. vivax being a major challenge for its control. Several studies have indicated metabolomics as a promising tool for combating the disease. The study evaluated plasma metabolomic prof
Externí odkaz:
https://doaj.org/article/ebfb6b0aff804efc93980cbaba6c5447
Autor:
Deborah V. A. de Aguiar, Jussara V. Roque, Leomir A. S. de Lima, Iris M. Junior, Helineia O. Gomes, Emanoel N. R. de Sousa, Gláucia P. L. Piccoli, Boniek G. Vaz
Publikováno v:
ACS Omega, Vol 9, Iss 9, Pp 10415-10425 (2024)
Externí odkaz:
https://doaj.org/article/68b3d755ecc64a7fad414d03a7438292
Autor:
Victor I. Mwangi, Rebeca L. A. Netto, Mayla G. S. Borba, Gabriel F. Santos, Gesiane S. Lima, Lucas S. Machado, Michael N. Yakubu, Fernando F. A. Val, Vanderson S. Sampaio, Marco A. Sartim, Hector H. F. Koolen, Allyson G. Costa, Maria C. M. Toméi, Tiago P. Guimarães, Andrea R. Chaves, Boniek G. Vaz, Marcus V. G. Lacerda, Wuelton M. Monteiro, Luiz G. Gardinassi, Gisely C. Melo
Publikováno v:
mSystems, Vol 8, Iss 6 (2023)
ABSTRACT Corticosteroids have become a choice for managing severe COVID-19, but the molecular mechanisms behind the response after corticosteroid administration remain incompletely understood. In order to unravel this, comparisons between temporal me
Externí odkaz:
https://doaj.org/article/09c789c98cfa426b9292889737d65fd4
Autor:
Marcelo V. S. Alves, Lanaia I. L. Maciel, João O. S. Passos, Camilo L. M. Morais, Marfran C. D. dos Santos, Leomir A. S. Lima, Boniek G. Vaz, Rodrigo Pegado, Kássio M. G. Lima
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract This study performs a chemical investigation of blood plasma samples from patients with and without fibromyalgia, combined with some of the symptoms and their levels of intensity used in the diagnosis of this disease. The symptoms evaluated
Externí odkaz:
https://doaj.org/article/4b38cbe14d124a6d972b49a62fff6b1f
Autor:
Marcelo V. S. Alves, Lanaia I. L. Maciel, Ruver R. F. Ramalho, Leomir A. S. Lima, Boniek G. Vaz, Camilo L. M. Morais, João O. S. Passos, Rodrigo Pegado, Kássio M. G. Lima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Fibromyalgia is a rheumatological disorder that causes chronic pain and other symptomatic conditions such as depression and anxiety. Despite its relevance, the disease still presents a complex diagnosis where the doctor needs to have a corre
Externí odkaz:
https://doaj.org/article/e2bce6dbd4b643dba89e88019d0668ef
Autor:
LUCIANA G.P. SODRÉ, LAERCIO L. MARTINS, LORRAINE LOUISE G.C. DE ARAUJO, DANIELLE M.M. FRANCO, BONIEK G. VAZ, WANDERSON ROMÃO, VALÉRIA M. MERZEL, GEORGIANA F. DA CRUZ
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 94, Iss suppl 3 (2022)
Abstract Biosurfactants and waterflooding have been widely reported thus far for enhancing oil production. Nevertheless, there is a lack of literature to explore enhanced oil recovered methods effects on its chemical composition. The aim of this work
Externí odkaz:
https://doaj.org/article/ad7a5182356247bc9a45cede761ac645
Autor:
Ana Cláudia M. Ramos, Kênnia R. Rezende, Carolina M. Teixeira, Aline R. Fernandes, Heloa Santos, Rúbia Darc Machado, Ricardo Menegatti, Boniek G. Vaz, Andréa R. Chaves
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 930 (2023)
The LQFM05 is a prototype drug designed for treatment of psychiatric disorders, such as schizophrenia, exhibiting anxiolytic- and antidepressant-like (12 or 24 µmol/kg) effects in classical behavioral tests. In order to evaluate its pharmacokinetic
Externí odkaz:
https://doaj.org/article/67ade06354944e60bed08b54df23d66c
Autor:
Nerilson M. Lima, Gesiane S. Lima, Gabriel F. dos Santos, Gagan Preet, Lanaia I. L. Maciel, Teresinha de Jesus A. S. Andrade, Marcel Jaspars, Andrea R. Chaves, Boniek G. Vaz
Publikováno v:
Metabolites, Vol 13, Iss 3, p 367 (2023)
Employing a combination of liquid chromatography electrospray ionization and paper spray ionization high-resolution tandem mass spectrometry, extracts from cupuassu (Theobroma grandiflorum) pulp prepared with either water, methanol, acetonitrile or c
Externí odkaz:
https://doaj.org/article/3e811317ce994c26a712dc86d4341c19
Autor:
Gesiane S. Lima, Nerilson M. Lima, Jussara V. Roque, Deborah V. A. de Aguiar, João V. A. Oliveira, Gabriel F. dos Santos, Andrea R. Chaves, Boniek G. Vaz
Publikováno v:
Molecules, Vol 27, Iss 22, p 7937 (2022)
The liquid chromatography–mass spectrometry (LC-MS)-based metabolomics approach is a powerful technology for discovering novel biologically active molecules. In this study, we investigated the metabolic profiling of Orchidaceae species using LC-HRM
Externí odkaz:
https://doaj.org/article/3847834390724d62b077c7ec26f0435e
Autor:
Lanussy P. de Oliveira, Iziara F. Florentino, Daiany P.B. Silva, Francine Pazini, Flávio S. de Carvalho, Germán Sanz, Boniek G. Vaz, Fábio F. da Rocha, James O. Fajemiroye, Paulo C. Ghedini, Luciano M. Lião, Ricardo Menegatti, Elson A. Costa, Thiago S. de Oliveira
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 101:216-225
Molecular modification of compounds remains important strategy towards the discovery of new drugs. In this sense, this study presents a new pyrazole derivative 5-(1-(2-fluorophenyl)-1 H-pyrazol-4-yl)-1 H-tetrazole (LQFM039) and evaluated the anti-inf