Výsledky vyhledávání - "Bongsup P. Cho"

Akademický článek

Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Aminobiphenyl-Modified DNA

Autor: Ang Cai, Ke Bian, Fangyi Chen, Qi Tang, Rachel Carley, Deyu Li, Bongsup P. Cho

Publikováno v: Molecules, Vol 24, Iss 8, p 1566 (2019)

Bulky organic carcinogens are activated in vivo and subsequently react with nucleobases of cellular DNA to produce adducts. Some of these DNA adducts exist in multiple conformations that are slowly interconverted to one another. Different conformatio

Externí odkaz: https://doaj.org/article/8143529f9c5648e698dcc5e7c8f78cc6

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Probing the Interactions of Perfluorocarboxylic Acids of Various Chain Lengths with Human Serum Albumin: Calorimetric and Spectroscopic Investigations

Autor: Alicia M. Crisalli, Ang Cai, Bongsup P. Cho

Publikováno v: Chemical Research in Toxicology. 36:703-713

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d008dc9bebb140ae78747b0f8edd8d28
https://doi.org/10.1021/acs.chemrestox.3c00011

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Inhibitory Effects and Surface Plasmon Resonance-Based Binding Affinities of Dietary Hydrolyzable Tannins and Their Gut Microbial Metabolites on SARS-CoV-2 Main Protease

Autor: Hang Ma, Bongsup P. Cho, Dongli Li, Feng Xu, Huifang Li, Navindra P. Seeram, Joel A. Dain, Chang Liu, Ang Cai

Publikováno v: Journal of Agricultural and Food Chemistry

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) main protease (Mpro) inhibitors are considered as potential treatments for coronavirus disease 2019, and dietary polyphenols show promise in SARS-CoV-2 Mpro inhibition based on in silico stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e0471c920d3559638490b7c5fab33e
https://doi.org/10.1021/acs.jafc.1c03521

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Characterization of molecular interactions between cannabidiol and human plasma proteins (serum albumin and γ-globulin) by surface plasmon resonance, microcalorimetry, and molecular docking

Autor: Chang Liu, Ang Cai, Huifang Li, Ni Deng, Bongsup P. Cho, Navindra P. Seeram, Hang Ma

Publikováno v: Journal of pharmaceutical and biomedical analysis. 214

A cannabidiol (CBD) oral solution (Epidiolex®) has been approved by the United States Food and Drug Administration to treat seizure conditions. However, the biomedical and pharmaceutical applications of CBD are hindered partially due to a limited un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a6af44a8871ea565750a59c9a9a141
https://pubmed.ncbi.nlm.nih.gov/35398615

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Translational Research: The Time is Now

Autor: James F, Padbury, Bongsup P, Cho

Publikováno v: Rhode Island medical journal (2013). 104(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b2a6c27e3e130562d3e6a59964ce946
https://pubmed.ncbi.nlm.nih.gov/33789402

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RI-INBRE: A Statewide NIH Program Grant to Improve Institutional Biomedical Research Capacity in Rhode Island

Autor: Christopher L, Hemme, Laura, Bellavia, Bongsup P, Cho, Samantha, Meenach, Niall G, Howlett

Publikováno v: R I Med J (2013)

The overarching goal of Rhode Island-IDeA Network of Biomedical Research Excellence (RI-INBRE) is to improve institutional capacity for biomedical research excellence and expand student experiential training opportunities in the State of Rhode Island

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f5e68a7d62529910a95f8d40895bf2f
https://pubmed.ncbi.nlm.nih.gov/33648315

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DNA base sequence effects on bulky lesion-induced conformational heterogeneity during DNA replication

Autor: Stacey D. Wetmore, Ang Cai, Bongsup P. Cho, Satyakam Patnaik, Katie A. Wilson

Publikováno v: Nucleic Acids Research

4-Aminobiphenyl (ABP) and its structure analog 2-aminofluorene (AF) are well-known carcinogens. In the present work, an unusual sequence effect in the 5′-CTTCTG1G2TCCTCATTC-3′ DNA duplex is reported for ABP- and AF-modified G. Specifically, the A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40d99ade4292a4ee875f3965aa621f0
https://doi.org/10.1093/nar/gky409

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Characterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1‑Methyladenine and 3‑Methylcytosine

Autor: Fangyi Chen, James C. Delaney, Ke Bian, Bongsup P. Cho, Alvin C. Bach, Deyu Li, Qi Tang, Fatemeh Akhlaghi, Sravani Adusumalli, Ang Cai

Publikováno v: ACS Omega, Vol 2, Iss 11, Pp 8205-8212 (2017)
ACS Omega

Oligonucleotides serve as important tools for biological, chemical, and medical research. The preparation of oligonucleotides through automated solid-phase synthesis is well-established. However, identification of byproducts generated from DNA synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ac3ca0fb5711255112b0de402eaca6
https://doaj.org/article/b780818fb48d4c32b8362ec673249501

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Conformational Insights into the Mechanism of Acetylaminofluorene-dG-Induced Frameshift Mutations in the NarI Mutational Hotspot

Autor: Lifang Xu, Bongsup P. Cho

Publikováno v: Chemical Research in Toxicology. 29:213-226

Frameshift mutagenesis encompasses the gain or loss of DNA base pairs, resulting in altered genetic outcomes. The NarI restriction site sequence 5′-G(1)G(2)CG(3)CX-3′ in Escherichia coli is a well-known mutational hotspot, in which lesioning of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc34e1946064e6c24b05bf14bfa56ce
https://doi.org/10.1021/acs.chemrestox.5b00484

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