Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bongiwe Ndlovu"'
Autor:
Ana Moyano, Bongiwe Ndlovu, Msizi Mbele, Kewreshini Naidoo, Nasreen Khan, Jaclyn K Mann, Thumbi Ndung'u
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286507 (2023)
Previous work suggests that HIV controllers with protective human leukocyte antigen class I alleles (VC+) possess a high breadth of Gag-specific CD8+ T cell responses, while controllers without protective alleles (VC-) have a different unknown mechan
Externí odkaz:
https://doaj.org/article/1036a0e035574194998ef71454b4da01
Autor:
Tawanda J. Chisango, Bongiwe Ndlovu, Arthur Vengesai, Agness Farai Nhidza, Edson P. Sibanda, Danai Zhou, Francisca Mutapi, Takafira Mduluza
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Schistosomiasis is a devastating parasitic disease. The mainstay of schistosomiasis control is by praziquantel treatment. The study aimed to determine benefits of annual chemotherapy of schistosomiasis on development of protective
Externí odkaz:
https://doaj.org/article/72d43a7abd6747ab8446f7d7fe8b810d
Autor:
Kimone Leigh Fisher, Jennifer M. Mabuka, Aida Sivro, Sinaye Ngcapu, Jo-Ann Shelley Passmore, Farzana Osman, Bongiwe Ndlovu, Quarraisha Abdool Karim, Salim S. Abdool Karim, Amy W. Chung, Cheryl Baxter, Derseree Archary
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The RV144 HIV-vaccine trial highlighted the importance of envelope-specific non-neutralizing antibody (nNAb) Fc-mediated functions as immune correlates of reduced risk of infection. Since pre-exposure prophylaxis (PrEP) and HIV-vaccines are being use
Externí odkaz:
https://doaj.org/article/71c1969aa4b74df88f67c6aa5d11bee3
Autor:
Tawanda Mandizvo, Nombali Gumede, Bongiwe Ndlovu, Siphiwe Ndlovu, Jaclyn K. Mann, Denis R. Chopera, Lanish Singh, Krista L. Dong, Bruce D. Walker, Zaza M. Ndhlovu, Christy L. Lavine, Michael S. Seaman, Kamini Gounder, Thumbi Ndung’u
Publikováno v:
Journal of virology. 96(24)
Broadly neutralizing antibodies (bNAbs) for HIV-1 prevention or cure strategies must inhibit transmitted/founder and reservoir viruses. Establishing sensitivity of circulating viruses to bNAbs and genetic patterns affecting neutralization variability
Autor:
Lynn Morris, Bongiwe Ndlovu, Tandile Hermanus, Penny L. Moore, Thumbi Ndung'u, Ivelin S. Georgiev, Bruce D. Walker, Nagarajan Raju, Kim Robertson, Qiniso Mthethwa, Daniel M. Muema, Kamini Gounder
Publikováno v:
Virology
Broadly neutralizing antibodies (bNAbs) may constitute an essential component of a protective vaccine against HIV-1, yet no immunogen has been able to elicit them. To characterize the development of bNAbs in HIV-1 subtype C infected individuals, a pa
Autor:
Amy W. Chung, Jenniffer M. Mabuka, Yathisha Ramlakhan, Philip J. R. Goulder, Bongiwe Ndlovu, Musie Ghebremichael, Bruce D. Walker, Hannah Robinson, Galit Alter, Anna Licht, Thumbi Ndung'u, Tarylee Reddy
Publikováno v:
AIDS
OBJECTIVE: Postinfection HIV viral control and immune correlates analysis of the RV144 vaccine trial indicate a potentially critical role for Fc receptor-mediated antibody functions. However, the influence of functional antibodies in clade C infectio
Autor:
Edson Panganayi Sibanda, Bongiwe Ndlovu, Francisca Mutapi, Agness Farai Nhidza, Takafira Mduluza, Tawanda Chisango, Arthur Vengesai, Danai Zhou
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)
Background Schistosomiasis is a devastating parasitic disease. The mainstay of schistosomiasis control is by praziquantel treatment. The study aimed to determine benefits of annual chemotherapy of schistosomiasis on development of protective immunity
Autor:
Bongiwe Ndlovu, Nasreen Ismail, Thumbi Ndung'u, Zaza M. Ndhlovu, Bruce D. Walker, Omolara Baiyegunhi, Funsho Ogunshola
Publikováno v:
Journal of Virology
Despite decades of focused research, the field has yet to develop a prophylactic vaccine. In the RV144 vaccine trial, non-neutralizing antibody responses were identified as a correlate for prevention of HIV acquisition. However, factors that predict